Serine 380 (P14) → glutamate mutation activates antithrombin as an inhibitor of factor Xa

Journal of Biological Chemistry

Volumn 275, Issue 6, 2000, Pages 4092-4098

  Futamura, Akiko ^a   Gettins, Peter G W ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR 10A INHIBITOR; HEPARIN;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME INHIBITION; PRIORITY JOURNAL; PROTEIN BINDING; STOICHIOMETRY;

ANTITHROMBINS; CIRCULAR DICHROISM; FACTOR XA; HEPARIN; KINETICS; MUTATION; PROTEIN STRUCTURE, SECONDARY; SERPINS; SPECTROMETRY, FLUORESCENCE; TRYPSIN;

EID: 0034635357     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.6.4092     Document Type: Article

References (33)

1. Olson, S. T., and Björk, I. (1994) Perspect. Drug Discov. Des. 1, 479-501
2. Olson, S. T., and Björk, I. (1991) J. Biol. Chem. 266, 6353-6364
3. Rezaie, A. R. (1998) J. Biol. Chem. 273, 16824-16827
4. Gettins, P. G. W., Fan, B., Crews, B. C., Turko, I. V., Olson, S. T., and Streusand, V. J. (1993) Biochemistry 32, 8385-8389
5. Huntington, J. A., Olson, S. T., Fan, B., and Gettins, P. G. W. (1996) Biochemistry 35, 8495-8503
6. Huntington, J. A., and Gettins, P. G. W. (1998) Biochemistry 37, 3272-3277
7. Schreuder, H. A., de Boer, B., Dijkema, R, Mulders, J., Theunissen, H. J. M., Grootenhuis, P. D. J., and Hol, W. G. J. (1994) Nat. Struct. Biol. 1, 48-54
8. van Boeckel, C. A. A., Grootenhuis, P. D. J., and Visser, A. (1994) Nat. Struct. Biol. 1, 423-425
9. Carrell, R. W., Stein, P. E., Fermi, G., and Wardell, M. R. (1994) Structure 2, 257-270
10. Skinner, R., Abrahams, J.-P., Whisstock, J. C., Lesk, A. M., Carrell, R. W., and Wardell, M. R. (1997) J. Mol. Biol. 266, 601-609
11. Jin, L., Abrahams, J. P., Skinner, R., Petitou, M., Pike, R. N., and Carrell, R. W. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 14683-14688
12. Stratikos, E., and Gettins, P. G. W. (1998) J. Biol. Chem. 273, 15582-15589
13. Stratikos, E., and Gettins, P. G. W. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4808-4813
14. Fan, B., Crews, B. C., Turko, I. V., Choay, J., Zettlmeißl, G., and Gettins, P. (1993) J. Biol. Chem. 268, 17588-17596
15. Turko, I. V., Fan, B., and Gettins, P. G. W. (1993) FEBS Lett. 335, 9-12
16. Fan, B., Turko, I. V., and Gettins, P. G. W. (1994) Biochemistry 33, 14156-14161
17. Zettlmeiβl, G., Wirth, M., Hauser, H., and Küpper, H. A. (1988) Behring Inst. Mitt. 82, 26-34
18. Olson, S. T., Frances-Chmura, A. M., Swanson, R., Björk, I., and Zettlmeissl, G. (1997) Arch. Biochem. Biophys. 341, 212-221
19. Nordenman, B., Nyström, C., and Björk, I. (1977) Eur. J. Biochem. 78, 195-203
20. Pace, C. N., Vajdos, F., Grimsley, G., and Gray, T. (1995) Protein Sci. 4, 2411-2423
21. Olson, S. T., Björk, I., and Shore, J. D. (1993) Methods Enzymol. 222, 525-559
22. Bock, P. E., Craig, P. A., Olson, S. T., and Singh, P. (1989) Arch. Biochem. Biophys. 273, 375-388
23. Miletich, J. P., Broze, G. J., Jr., and Majerus, P. W. (1980) Anal. Biochem. 105, 304-310
24. Lanchantin, G. F., Friedmann, J. A., and Hart, D. W. (1973) J. Biol. Chem. 248, 5956-5966
25. Olson, S. T., Björk, I., Sheffer, R., Craig, P. A., Shore, J. D., and Choay, J. (1992) J. Biol. Chem. 267, 12528-12538
26. Olson, S. T., and Shore, J. D. (1981) J. Biol. Chem. 256, 11065-11072
27. Meagher, J. L., Beechem, J. M., Olson, S. T., and Gettins, P. G. W. (1998) J. Biol. Chem. 273, 23283-23289
28. Kaslik, G., Patthy, A., Bálint, M., and Gráf, L. (1995) FEBS Lett. 370, 179-183
29. Kaslik, G., Kardos, J., Szabó, L., Závodszky, P., Westler, W. M., Markley, J. L., and Gráf, L. (1997) Biochemistry 36, 5455-5474
30. Plotnick, M. I., Mayne, L., Schechter, N. M., and Rubin, H. (1996) Biochemistry 35, 7586-7590
31. Hood, D. B., Huntington, J. A., and Gettins, P. G. W. (1994) Biochemistry 33, 8538-8547
32. Lukacs, C. M., Zhong, J. Q., Plotnick, M. I., Rubin, H., Cooperman, B. S., and Christianson, D. W. (1996) Nat. Struct. Biol. 3, 888-893
33. Olson, S. T. (1985) J. Biol. Chem. 260, 10153-10160