Partial loss of Smad7 function impairs bone remodeling, osteogenesis and enhances osteoclastogenesis in mice

Bone

Volumn 67, Issue , 2014, Pages 46-55

  Li, Nan ^a   Lee, Wayne Yuk Wai ^a   Lin, Si En ^a   Ni, Ming ^a   Zhang, Ting ^a   Huang, Xiao Ru ^a   Lan, Hui Yao ^a   Li, Gang ^a,b  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Bone remodeling; MSCs; Osteoclastogenesis; Osteogenesis; Smad7

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ALKALINE PHOSPHATASE; CALCITONIN RECEPTOR; CCAAT ENHANCER BINDING PROTEIN ALPHA; COMPLEMENT FACTOR D; FAT DROPLET; OSTEOCALCIN; SMAD7 PROTEIN; TRANSCRIPTION FACTOR RUNX2; SMAD7 PROTEIN, MOUSE;

ADIPOGENESIS; ADIPSIN GENE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE REMODELING; C EBPA GENE; CELL DIFFERENTIATION; CELL SURFACE; COL1A1 GENE; CONTROLLED STUDY; CTR GENE; ENZYME ACTIVITY; EXON; FEMUR; GENE; GENE DELETION; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MALE; MESENCHYMAL STEM CELL; METAPHYSIS; MOUSE; NONHUMAN; OCN GENE; OSSIFICATION; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PROTEIN FUNCTION; RUNX2 GENE; SMAD7 GENE; TRAP GENE; ANIMAL; BONE MARROW CELL; CELL PROLIFERATION; CYTOLOGY; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY;

ANIMALS; BONE MARROW CELLS; BONE REMODELING; CELL DIFFERENTIATION; CELL PROLIFERATION; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, KNOCKOUT; OSTEOCLASTS; OSTEOGENESIS; SMAD7 PROTEIN;

EID: 84904312511     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2014.06.033     Document Type: Article

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