Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing

Experimental and Molecular Pathology

Volumn 90, Issue 1, 2011, Pages 107-115

  Kawakatsu, Motohisa ^a   Kanno, Seiji ^a   Gui, Ting ^a   Gai, Zhibo ^a   Itoh, Shunji ^a   Tanishima, Hiroyuki ^a   Oikawa, Kosuke ^a   Muragaki, Yasuteru ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Bone fracture; Callus formation; Healing; Smad3; TGF

Indexed keywords

MESSENGER RNA; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; CALLUS; CELL DIFFERENTIATION; CELL MATURATION; CHONDROGENESIS; CONTROLLED STUDY; FEMALE; FRACTURE HEALING; GENE EXPRESSION; HISTOPATHOLOGY; MOUSE; NONHUMAN; OPEN FRACTURE; OSTEOBLAST; OSTEOCLAST; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TIBIA FRACTURE; WILD TYPE;

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; ANIMALS; BONY CALLUS; CELL DIFFERENTIATION; CHONDROGENESIS; FEMALE; FRACTURE HEALING; ISOENZYMES; MICE; MICE, KNOCKOUT; OSTEOCLASTS; OSTEOGENESIS; RNA, MESSENGER; SMAD3 PROTEIN; SOX9 TRANSCRIPTION FACTOR; TIBIA; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 78650706502     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2010.10.011     Document Type: Article

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