Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis

American Journal of Physiology - Renal Physiology

Volumn 307, Issue 2, 2014, Pages

  Gandhi, Rushi ^a,c   Yi, James ^a,c   Ha, Jihyen ^a   Shi, Hang ^a   Ismail, Ola ^a   Nathoo, Sahra ^a   Bonventre, Joseph V ^d   Zhang, Xizhong ^b,c   Gunaratnam, Lakshman ^a,b,c  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b WESTERN UNIVERSITY   (Canada)

^c LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Efferocytosis; Kidney injury molecule 1 (KIM 1); Proximal tubule epithelial cells (PTECs); Receptor; Shedding

Indexed keywords

HYDROGEN PEROXIDE; KIDNEY INJURY MOLECULE 1; LACTADHERIN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ACUTE KIDNEY FAILURE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVITY; CELL DAMAGE; CELL LYSATE; CELL MEMBRANE; CELL PHAGOCYTOSIS; CELL SURFACE; CONTROLLED STUDY; EFFEROCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; MEMBRANE BIOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECEPTOR SHEDDING; REPERFUSION INJURY; UPREGULATION;

EFFEROCYTOSIS; KIDNEY INJURY MOLECULE-1 (KIM-1); PROXIMAL TUBULE EPITHELIAL CELLS (PTECS); RECEPTOR; SHEDDING;

ACUTE KIDNEY INJURY; ADAM PROTEINS; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CULTURE MEDIA, CONDITIONED; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROGEN PEROXIDE; KIDNEY; LLC-PK1 CELLS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PHAGOCYTOSIS; RECEPTORS, VIRUS; SWINE; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS;

EID: 84904279596     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00638.2013     Document Type: Article

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