-
1
-
-
67649644872
-
Novel pharmacotherapies to abrogate postinfarction ventricular remodeling
-
Dorn GW: Novel pharmacotherapies to abrogate postinfarction ventricular remodeling. Nat Rev Cardiol 6: 283-291, 2009.
-
(2009)
Nat Rev Cardiol
, vol.6
, pp. 283-291
-
-
Dorn, G.W.1
-
2
-
-
84866434902
-
The use of ghrelin and ghrelin receptor agonists as a treatment for animal models of disease: Efficacy and mechanism
-
Deboer MD: The use of ghrelin and ghrelin receptor agonists as a treatment for animal models of disease: efficacy and mechanism. Curr Pharm Des 18: 4779-4799, 2012.
-
(2012)
Curr Pharm Des
, vol.18
, pp. 4779-4799
-
-
Deboer, M.D.1
-
3
-
-
84866403161
-
Clinical application of ghrelin
-
Strasser F: Clinical application of ghrelin. Curr Pharm Des 18: 4800-4812, 2012.
-
(2012)
Curr Pharm Des
, vol.18
, pp. 4800-4812
-
-
Strasser, F.1
-
4
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M, Hosoda H, Date Y, et al: Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402: 656-660, 1999.
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
-
5
-
-
84877943365
-
Ghrelin and the cardiovascular system
-
Isgaard J: Ghrelin and the cardiovascular system. Endocr Dev 25: 83-90, 2013.
-
(2013)
Endocr Dev
, vol.25
, pp. 83-90
-
-
Isgaard, J.1
-
6
-
-
79958082780
-
The effects of ghrelin on inflammation and the immune system
-
Baatar D, Patel K and Taub DD: The effects of ghrelin on inflammation and the immune system. Mol Cell Endocrinol 340: 44-58, 2011.
-
(2011)
Mol Cell Endocrinol
, vol.340
, pp. 44-58
-
-
Baatar, D.1
Patel, K.2
Taub, D.D.3
-
8
-
-
80053919482
-
Ghrelin promotes differentiation of human embryonic stem cells into cardiomyocytes
-
Yang J, Liu GQ, Wei R, et al: Ghrelin promotes differentiation of human embryonic stem cells into cardiomyocytes. Acta Pharmacol Sin 32: 1239-1245, 2011.
-
(2011)
Acta Pharmacol Sin
, vol.32
, pp. 1239-1245
-
-
Yang, J.1
Liu, G.Q.2
Wei, R.3
-
9
-
-
70449656984
-
Ghrelin inhibits post-infarct myocardial remodeling and improves cardiac function through anti-inflammation effect
-
Huang CX, Yuan MJ, Huang H, et al: Ghrelin inhibits post-infarct myocardial remodeling and improves cardiac function through anti-inflammation effect. Peptides 30: 2286-2291, 2009.
-
(2009)
Peptides
, vol.30
, pp. 2286-2291
-
-
Huang, C.X.1
Yuan, M.J.2
Huang, H.3
-
11
-
-
84866416553
-
Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat
-
Xu X, Ding F, Pang J, et al: Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol 303: H703-H711, 2012.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.303
-
-
Xu, X.1
Ding, F.2
Pang, J.3
-
12
-
-
84862740198
-
Ghrelin prevents incidence of malignant arrhythmia after acute myocardial infarction through vagal afferent nerves
-
Mao Y, Tokudome T, Otani K, et al: Ghrelin prevents incidence of malignant arrhythmia after acute myocardial infarction through vagal afferent nerves. Endocrinology 153: 3426-3434, 2012.
-
(2012)
Endocrinology
, vol.153
, pp. 3426-3434
-
-
Mao, Y.1
Tokudome, T.2
Otani, K.3
-
13
-
-
68949167649
-
A novel peptide ghrelin inhibits neural remodeling after myocardial infarction in rats
-
Yuan MJ, Huang CX, Tang YH, et al: A novel peptide ghrelin inhibits neural remodeling after myocardial infarction in rats. Eur J Pharmacol 618: 52-57, 2009.
-
(2009)
Eur J Pharmacol
, vol.618
, pp. 52-57
-
-
Yuan, M.J.1
Huang, C.X.2
Tang, Y.H.3
-
14
-
-
3042735648
-
The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans
-
Gnanapavan S, Kola B, Bustin SA, et al: The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metabol 87: 2988, 2002.
-
(2002)
J Clin Endocrinol Metabol
, vol.87
, pp. 2988
-
-
Gnanapavan, S.1
Kola, B.2
Bustin, S.A.3
-
15
-
-
10744220319
-
Expression of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in normal human testis and testicular tumors
-
Gaytan F, Barreiro ML, Caminos JE, et al: Expression of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in normal human testis and testicular tumors. J Clin Endocrinol Metab 89: 400-409, 2004.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 400-409
-
-
Gaytan, F.1
Barreiro, M.L.2
Caminos, J.E.3
-
16
-
-
33645572871
-
Ghrelin tissue distribution: Comparison between gene and protein expression
-
Ghelardoni S, Carnicelli V, Frascarelli S, et al: Ghrelin tissue distribution: comparison between gene and protein expression. J Endocrinol Invest 29: 115-121, 2006.
-
(2006)
J Endocrinol Invest
, vol.29
, pp. 115-121
-
-
Ghelardoni, S.1
Carnicelli, V.2
Frascarelli, S.3
-
17
-
-
2442515963
-
Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes
-
Iglesias MJ, Pineiro R, Blanco M, et al: Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes. Cardiovasc Res 62: 481-488, 2004.
-
(2004)
Cardiovasc Res
, vol.62
, pp. 481-488
-
-
Iglesias, M.J.1
Pineiro, R.2
Blanco, M.3
-
18
-
-
81755184320
-
Structures and molecular forms of the ghrelin-family peptides
-
Nishi Y, Yoh J, Hiejima H and Kojima M: Structures and molecular forms of the ghrelin-family peptides. Peptides 32: 2175-2182, 2011.
-
(2011)
Peptides
, vol.32
, pp. 2175-2182
-
-
Nishi, Y.1
Yoh, J.2
Hiejima, H.3
Kojima, M.4
-
19
-
-
0029947291
-
Signal transduction systems employed by synthetic GH-releasing peptides in somatotrophs
-
Chen C, Wu D, Clarke IJ: Signal transduction systems employed by synthetic GH-releasing peptides in somatotrophs. J Endocrinol 148: 381-386, 1996.
-
(1996)
J Endocrinol
, vol.148
, pp. 381-386
-
-
Chen, C.1
Wu, D.2
Clarke, I.J.3
-
20
-
-
61849088939
-
C-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and-dependent mechanisms
-
Lodeiro M, Theodoropoulou M, Pardo M, et al: c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and-dependent mechanisms. PLoS One 4: e4686, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Lodeiro, M.1
Theodoropoulou, M.2
Pardo, M.3
-
21
-
-
34548487757
-
Stimulation by ghrelin of p42/p44 mitogen-activated protein kinase through the GHS-R1a receptor: Role of G-proteins and beta-arrestins
-
Camiña JP, Lodeiro M, Ischenko O, et al: Stimulation by ghrelin of p42/p44 mitogen-activated protein kinase through the GHS-R1a receptor: role of G-proteins and beta-arrestins. J Cell Physiol 213: 187-200, 2007.
-
(2007)
J Cell Physiol
, vol.213
, pp. 187-200
-
-
Camiña, J.P.1
Lodeiro, M.2
Ischenko, O.3
-
22
-
-
79955660779
-
Effects and mechanisms of ghrelin on cardiac microvascular endothelial cells in rats
-
Wang Y, Narsinh K, Zhao L, et al: Effects and mechanisms of ghrelin on cardiac microvascular endothelial cells in rats. Cell Biol Int 35: 135-140, 2011.
-
(2011)
Cell Biol Int
, vol.35
, pp. 135-140
-
-
Wang, Y.1
Narsinh, K.2
Zhao, L.3
-
23
-
-
80053188649
-
Ghrelin induces cell migration through GHS-R, CaMKII, AMPK, and NF-κB signaling pathway in glioma cells
-
Chen JH, Huang SM, Chen CC, et al: Ghrelin induces cell migration through GHS-R, CaMKII, AMPK, and NF-κB signaling pathway in glioma cells. J Cell Biochem 112: 2931-2941, 2011.
-
(2011)
J Cell Biochem
, vol.112
, pp. 2931-2941
-
-
Chen, J.H.1
Huang, S.M.2
Chen, C.C.3
-
24
-
-
36849039489
-
Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor
-
Holliday ND, Holst B, Rodionova EA, et al: Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor. Mol Endocrinol 21: 3100-3112, 2007.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 3100-3112
-
-
Holliday, N.D.1
Holst, B.2
Rodionova, E.A.3
-
25
-
-
33947188045
-
Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells
-
Iantorno M, Chen H, Kim JA, et al: Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells. Am J Physiol Endocrinol Metab 292: E756-E764, 2007.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Iantorno, M.1
Chen, H.2
Kim, J.A.3
-
26
-
-
47949094078
-
Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation
-
Xu X, Jhun BS, Ha CH and Jin ZG: Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation. Endocrinology 149: 4183-4192, 2008.
-
(2008)
Endocrinology
, vol.149
, pp. 4183-4192
-
-
Xu, X.1
Jhun, B.S.2
Ha, C.H.3
Jin, Z.G.4
-
27
-
-
84876675775
-
Ghrelin induces cell migration through GHSR1a-mediated PI3K/Akt/eNOS/NO signaling pathway in endothelial progenitor cells
-
Chen X, Chen Q, Wang L and Li G: Ghrelin induces cell migration through GHSR1a-mediated PI3K/Akt/eNOS/NO signaling pathway in endothelial progenitor cells. Metabolism 62: 743-752, 2013.
-
(2013)
Metabolism
, vol.62
, pp. 743-752
-
-
Chen, X.1
Chen, Q.2
Wang, L.3
Li, G.4
-
28
-
-
84859788175
-
Ghrelin signaling in heart remodeling of adult obese mice
-
Lacerda-Miranda G, Soares VM, Vieira AK, et al: Ghrelin signaling in heart remodeling of adult obese mice. Peptides 35: 65-73, 2012.
-
(2012)
Peptides
, vol.35
, pp. 65-73
-
-
Lacerda-Miranda, G.1
Soares, V.M.2
Vieira, A.K.3
-
29
-
-
84859485950
-
Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium
-
Ma Y, Zhang L, Edwards JN, et al: Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium. PLoS One 7: e35265, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Ma, Y.1
Zhang, L.2
Edwards, J.N.3
-
30
-
-
84855998730
-
Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI)
-
Kanashiro-Takeuchi RM, Takeuchi LM, Rick FG, et al: Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI). Proc Natl Acad Sci USA 109: 559-563, 2012.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 559-563
-
-
Kanashiro-Takeuchi, R.M.1
Takeuchi, L.M.2
Rick, F.G.3
-
31
-
-
77249162694
-
Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction
-
Kanashiro-Takeuchi RM, Tziomalos K, Takeuchi LM, et al: Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction. Proc Natl Acad Sci USA 107: 2604-2609, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2604-2609
-
-
Kanashiro-Takeuchi, R.M.1
Tziomalos, K.2
Takeuchi, L.M.3
-
32
-
-
58149503669
-
Growth hormone-releasing hormone as an agonist of the ghrelin receptor GHS-R1a
-
Casanueva FF, Camina JP, Carreira MC, et al: Growth hormone-releasing hormone as an agonist of the ghrelin receptor GHS-R1a. Proc Natl Acad Sci USA 105: 20452-20457, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20452-20457
-
-
Casanueva, F.F.1
Camina, J.P.2
Carreira, M.C.3
-
33
-
-
78049483949
-
Altered myocardial expression of ghrelin and its receptor (GHSR-1a) in patients with severe heart failure
-
Beiras-Fernandez A, Kreth S, Weis F, et al: Altered myocardial expression of ghrelin and its receptor (GHSR-1a) in patients with severe heart failure. Peptides 31: 2222-2228, 2010.
-
(2010)
Peptides
, vol.31
, pp. 2222-2228
-
-
Beiras-Fernandez, A.1
Kreth, S.2
Weis, F.3
-
34
-
-
84855338224
-
Chronic Akt blockade aggravates pathological hypertrophy and inhibits physiological hypertrophy
-
Buss SJ, Riffel JH, Malekar P, et al: Chronic Akt blockade aggravates pathological hypertrophy and inhibits physiological hypertrophy. Am J Physiol Heart Circ Physiol 302: H420-H430, 2012.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
-
-
Buss, S.J.1
Riffel, J.H.2
Malekar, P.3
-
35
-
-
77956959192
-
Inhibition of MAPK signaling by eNOS gene transfer improves ventricular remodeling after myocardial infarction through reduction of inflammation
-
Chen LL, Zhu TB, Yin H, et al: Inhibition of MAPK signaling by eNOS gene transfer improves ventricular remodeling after myocardial infarction through reduction of inflammation. Mol Biol Rep 37: 3067-3072, 2010. 1. Moding EJ, Kastan MB and Kirsch DG: Strategies for optimizing the response of cancer and normal tissues to radiation. Nat Rev Drug Discov 12: 526-542, 2013.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 526-542
-
-
Chen, L.L.1
Zhu, T.B.2
Yin, H.3
|