Ghrelin prevents incidence of malignant arrhythmia after acute myocardial infarction through vagal afferent nerves

Endocrinology

Volumn 153, Issue 7, 2012, Pages 3426-3434

  Mao, Yuanjie ^a   Tokudome, Takeshi ^a   Otani, Kentaro ^a   Kishimoto, Ichiro ^a   Nakanishi, Michio ^a   Hosoda, Hiroshi ^a   Miyazato, Mikiya ^a   Kangawa, Kenji ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE METHYL BROMIDE; CAPSAICIN; GHRELIN;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CARDIAC SYMPATHETIC NERVE ACTIVITY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DIASTOLIC BLOOD PRESSURE; HEART ARRHYTHMIA; HEART RATE; HEART RATE VARIABILITY; HISTOPATHOLOGY; MALE; MALIGNANT ARRHYTHMIA; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN PROCESSING; SENSORY NERVE; SURVIVAL RATE; SYMPATHETIC NERVE; SYSTOLIC BLOOD PRESSURE; VAGAL AFFERENT NERVE; VAGUS NERVE;

ANIMALS; ARRHYTHMIAS, CARDIAC; ATROPINE DERIVATIVES; BLOOD PRESSURE; CAPSAICIN; CATECHOLAMINES; ELECTROCARDIOGRAPHY; GHRELIN; HEART RATE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MYOCARDIAL INFARCTION; NEURONS, AFFERENT; TIME FACTORS; VAGUS NERVE;

EID: 84862740198     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1065     Document Type: Article

References (34)

1. Jardine DL, Charles CJ, Ashton RK, Bennett SI, Whitehead M, Frampton CM, Nicholls MG 2005 Increased cardiac sympathetic nerve activity following acute myocardial infarction in a sheep model. J Physiol 565:325-333 (Pubitemid 40723712)
2. Sutton MG, Sharpe N 2000 Left ventricular remodeling after myocardial infarction: pathophysiology and therapy. Circulation 101:2981-2988
3. Nishiue T, Tsuji H, Tarumi N, Tokunaga S, Tamura K, Masaki M, Inada M, Iwasaka T 1999 Heart rate variability and left ventricular dilatation early after myocardial infarction. J Electrocardiol 32:263-268 (Pubitemid 29380164)
4. Udelson JE, Patten RD, Konstam MA 2003 New concepts in post-infarction ventricular remodeling. Rev Cardiovasc Med 4:S3-S12 (Pubitemid 37220650)
5. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K 1999 Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:656-660 (Pubitemid 129516334)
6. Gnanapavan S, Kola B, Bustin SA, Morris DG, McGee P, Fairclough P, Bhattacharya S, Carpenter R, Grossman AB, Korbonits M 2002 The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metab 87:2988-2991 (Pubitemid 34655375)
7. Iglesias MJ, Piñeiro R, Blanco M, Gallego R, Diéguez C, Gualillo O, Gonzá lez-Juanatey JR, Lago F 2004 Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes. Cardiovasc Res 62:481-488
8. Nagaya N, Uematsu M, Kojima M, Ikeda Y, Yoshihara F, Shimizu W, Hosoda H, Hirota Y, Ishida H, Mori H, Kangawa K 2001 Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure. Circulation 104:1430-1435 (Pubitemid 32880158)
9. Nagaya N, Kangawa K 2003 Ghrelin improves left ventricular dysfunction and cardiac cachexia in heart failure. Curr Opin Pharmacol 3:146-151 (Pubitemid 36411238)
10. Schwenke DO, Tokudome T, Kishimoto I, Horio T, Shirai M, Cragg PA, Kangawa K 2008 Early ghrelin treatment after myocardial infarction prevents an increase in cardiac sympathetic tone and reduces mortality. Endocrinology 149:5172-5176
11. Matsumura K, Tsuchihashi T, Fujii K, Abe I, Iida M 2002 Central ghrelin modulates sympathetic activity in conscious rabbits. Hypertension 40:694-699 (Pubitemid 35278606)
12. Lin Y, Matsumura K, Fukuhara M, Kagiyama S, Fujii K, Iida M 2004 Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats. Hypertension 43:977-982 (Pubitemid 38579901)
13. Soeki T, Kishimoto I, Schwenke DO, Tokudome T, Horio T, Yoshida M, Hosoda H, Kangawa K 2008 Ghrelin suppresses cardiac sympathetic activity and prevents early left ventricular remodeling in rats with myocardial infarction. Am J Physiol Heart Circ Physiol 294:H426-H432
14. Hosoda H, Kojima M, Matsuo H, Kangawa K 2000 Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem Biophys Res Commun 279:909-913 (Pubitemid 32042875)
15. Arnold AC, Isa K, Shaltout HA, Nautiyal M, Ferrario CM, Chappell MC, Diz DI 2010 Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus. Am J Physiol Heart Circ Physiol 299:H763-H771
16. Thireau J, Zhang BL, Poisson D, Babuty D 2008 Heart rate variability in mice: a theoretical and practical guide. Exp Physiol 93:83-94 (Pubitemid 350293971)
17. Date Y, Murakami N, Toshinai K, Matsukura S, Niijima A, Matsuo H, Kangawa K, Nakazato M 2002 The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 123:1120-1128
18. Schelegle ES, Alfaro MF, Putney L, Stovall M, Tyler N, Hyde DM 2001 Effect of C-fiber-mediated, ozone-induced rapid shallow breathing on airway epithelial injury in rats. J Appl Physiol 91:1611-1618 (Pubitemid 32900351)
19. Hamalainen MM, Subieta A, Arpey C, Brennan TJ 2009 Differential effect of capsaicin treatment on pain related behaviors after plantar incision. J Pain 10:637-645
20. Thayer JF, Yamamoto SS, Brosschot JF 2010 The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors. Int J Cardiol 141:122-131
21. Brown AM, Malliani A 1971 Spinal sympathetic reflexes initiated by coronary receptors. J Physiol 212:685-705
22. Malliani A, Schwartz PJ, Zanchetti A 1969 A sympathetic reflex elicited by experimental coronary occlusion. Am J Physiol 217:703-709
23. Ninomiya I, Matsukawa K, Honda T, Nishiura N, Shirai M 1986 Cardiac sympathetic nerve activity and heart rate during coronary occlusion in awake cats. Am J Physiol 251(3 Pt 2):H528-H537
24. Kanaya N, Nakayama M, Kobayashi I, Fujita S, Namiki A 1998 Effect of isoflurane on epinephrine-induced arrhythmias in ischemic-reperfused dog hearts. Res Commun Mol Pathol Pharmacol 100:181-186 (Pubitemid 28313449)
25. Janssen BJ, De Celle T, Debets JJ, Brouns AE, Callahan MF, Smith TL 2004 Effects of anesthetics on systemic hemodynamics in mice. Am J Physiol Heart Circ Physiol 287:H1618-H1624 (Pubitemid 39313266)
26. Ríha H, Neckář J, Papoušek F, Netuka I, Pirk J, Kolář F, Ošt'ádal B2011 Suppression of ischemic and reperfusion ventricular arrhythmias by inhalational anesthetic-induced preconditioning in the rat heart. Physiol Res 60:709-714
27. Kaye DM, Lefkovits J, Jennings GL, Bergin P, Broughton A, Esler MD 1995 Adverse consequences of high sympathetic nervous activity in the failing human heart. J Am Coll Cardiol 26:1257-1263
28. Kobashi M, Yanagihara M, Fujita M, Mitoh Y, Matsuo R 2009 Fourth ventricular administration of ghrelin induces relaxation of the proximal stomach in the rat. Am J Physiol Regul Integr Comp Physiol 296:R217-R223
29. Shimizu S, Akiyama T, Kawada T, Sonobe T, Kamiya A, Shishido T, Tokudome T, Hosoda H, Shirai M, Kangawa K, Sugimachi M 2011 Centrally administered ghrelin activates cardiac vagal nerve in anesthetized rabbits. Auton Neurosci 162:60-65
30. Minisi AJ 1998 Vagal cardiopulmonary reflexes after total cardiac deafferentation. Circulation 98:2615-2620 (Pubitemid 29001203)
31. Barron KW, Bishop VS 1981 The influence of vagal afferents on the left ventricular contractile response to intracoronary administration of catecholamines in the conscious dog. Circ Res 49:159-169 (Pubitemid 11093191)
32. Jones CM, Quinn MS, Minisi AJ 2008 Reflex control of sympathetic outflow and depressed baroreflex sensitivity following myocardial infarction. Auton Neurosci 141:46-53
33. Kishimoto I, Tokudome T, Schwenke DO, Soeki T, Hosoda H, Nagaya N, Kangawa K 2009 Therapeutic potential of ghrelin in cardiac diseases. Expert Rev Endocrinol Metab 4:283-289
34. Lambert E, Lambert G, Ika-Sari C, Dawood T, Lee K, Chopra R, Straznicky N, Eikelis N, Drew S, Tilbrook A, Dixon J, Esler M, Schlaich MP 2011 Ghrelin modulates sympathetic nervous system activity and stress response in lean and overweight men. Hypertension 58:43-50