Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signaling

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Vendelbo, Mikkel Holm ^a   Møller, Andreas Buch ^a   Christensen, Britt ^a   Nellemann, Birgitte ^a   Clasen, Berthil Frederik Forrest ^a   Nair, K Sreekumaran ^b   Jørgensen, Jens Otto Lunde ^a   Jessen, Niels ^a   Møller, Niels ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROGIN 1; BIOLOGICAL MARKER; INITIATION FACTOR 4E BINDING PROTEIN 1; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MUSCLE RING FINGER 1 PROTEIN; PHENYLALANINE; PROTEIN KINASE; PROTEIN S6; TYROSINE; UNCLASSIFIED DRUG; UNK 51 LIKE KINASE 1; AMINO ACID; FATTY ACID; GLUCAGON; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

AMINO ACID ANALYSIS; AMINO ACID COMPOSITION; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DIET RESTRICTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; INSULIN RESISTANCE; INTRACELLULAR SIGNALING; LIGHT CHAIN; MALE; MUSCLE BIOPSY; NORMAL HUMAN; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; SKELETAL MUSCLE; ANALYSIS OF VARIANCE; BLOOD; CROSSOVER PROCEDURE; ENERGY METABOLISM; MASS FRAGMENTOGRAPHY; METABOLISM; PHYSIOLOGY; RADIOIMMUNOASSAY; RANDOMIZED CONTROLLED TRIAL; SECRETION (PROCESS); SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMINO ACIDS; ANALYSIS OF VARIANCE; BLOTTING, WESTERN; CROSS-OVER STUDIES; ENERGY METABOLISM; FASTING; FATTY ACIDS, NONESTERIFIED; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUCAGON; HUMANS; MALE; MUSCLE, SKELETAL; PHENYLALANINE; RADIOIMMUNOASSAY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TYROSINE;

EID: 84904263764     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102031     Document Type: Article

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