Edaravone protected PC12 cells against MPP(+)-cytoxicity via inhibiting oxidative stress and up-regulating heme oxygenase-1 expression

Journal of the Neurological Sciences

Volumn 343, Issue 1-2, 2014, Pages 115-119

  Cheng, Baohua ^a   Guo, Yunliang ^b   Li, Chuangang ^c   Ji, Bingyuan ^a   Pan, Yanyou ^a   Chen, Jing ^a   Bai, Bo ^a  

^a JINING MEDICAL UNIVERSITY   (China)

^b SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c THE SECOND HOSPITAL OF SHANDONG UNIVERSITY   (China)

Author keywords

1 Methyl 4 phenylpyridinium; Edaravone; Heme oxygenase 1; Oxidative stress; Parkinson's disease; PC12

Indexed keywords

HEME OXYGENASE 1; NORPHENAZONE; PROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ENZYME INHIBITOR; HEME OXYGENASE; HMOX1 PROTEIN, RAT; NEUROTOXIN; PHENAZONE; PHENYLMETHYLPYRAZOLONE; PROTOPORPHYRIN; PROTOPORPHYRIN ZINC; SCAVENGER;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; NEUROPROTECTION; OXIDATIVE STRESS; PC12 CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANALYSIS OF VARIANCE; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; DRUG INTERACTION; FLOW CYTOMETRY; METABOLISM; RAT;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANALYSIS OF VARIANCE; ANIMALS; ANTIPYRINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; FLOW CYTOMETRY; FREE RADICAL SCAVENGERS; HEME OXYGENASE (DECYCLIZING); NEUROTOXINS; OXIDATIVE STRESS; PC12 CELLS; PROTOPORPHYRINS; RATS; UP-REGULATION;

EID: 84904251246     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2014.05.051     Document Type: Article

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