3-O-demethylswertipunicoside inhibits MPP+-induced oxidative stress and apoptosis in PC12 cells

Brain Research

Volumn 1508, Issue , 2013, Pages 53-62

  Zhou, Junjun ^a,b   Sun, Yi ^a,b   Zhao, Xin ^a,b   Deng, Zheng ^a,b   Pu, Xiaoping ^a,b  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

1 Methyl 4 phenylpyridinium; 3 O Demethylswertipunicoside; Apoptosis; Oxidative stress; Parkinson's disease; PC12 cells

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 3 O DEMETHYLSWERTIPUNICOSIDE; ALPHA SYNUCLEIN; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 9; MALONALDEHYDE; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NORPHENAZONE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; IN VITRO STUDY; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; PC12 CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

1-METHYL-4-PHENYLPYRIDINIUM; ALPHA-SYNUCLEIN; ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; DOPAMINE AGENTS; GLUCOSIDES; MALONDIALDEHYDE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PC12 CELLS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; XANTHONES;

SWERTIA PUNICEA;

EID: 84876113531     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.02.049     Document Type: Article

References (41)

1. B. Antonsson, F. Conti, A. Ciavatta, S. Montessuit, S. Lewis, I. Martinou, L. Bernasconi, A. Bernard, J.J. Mermod, G. Mazzei, K. Maundrell, F. Gambale, R. Sadoul, and J.C. Martinou Inhibition of Bax channel-forming activity by Bcl-2 Science 277 1997 370 372 (Pubitemid 27450709)
2. A. Autret, and S.J. Martin Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis Mol. Cell. 36 2009 355 363
3. B.R. Broughton, D.C. Reutens, and C.G. Sobey Apoptotic mechanisms after cerebral ischemia Stroke 40 2009 e331 9
4. L.S. Capettini, L.V. Campos, M.H. Dos Santos, T.J. Nagem, V.S. Lemos, and S.F. Cortes Vasodilator and antioxidant effect of xanthones isolated from Brazilian medicinal plants Planta Med. 75 2009 145 148
5. J. Carange, F. Longpre, B. Daoust, and M.G. Martinoli 24-Epibrassinolide, a phytosterol from the brassinosteroid family, protects dopaminergic cells against MPP-induced oxidative stress and apoptosis J. Toxicol. 2011 2011 392859
6. G.M. Cohen Caspases: the executioners of apoptosis Biochem. J. 326 Pt 1 1997 1 16 (Pubitemid 27386911)
7. S.P. Cregan, A. Fortin, J.G. MacLaurin, S.M. Callaghan, F. Cecconi, S.W. Yu, T.M. Dawson, V.L. Dawson, D.S. Park, G. Kroemer, and R.S. Slack Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death J. Cell Biol. 158 2002 507 517 (Pubitemid 34851709)
8. S.P. Cregan, V.L. Dawson, and R.S. Slack Role of AIF in caspase-dependent and caspase-independent cell death Oncogene 23 2004 2785 2796 (Pubitemid 38638842)
9. E. Daugas, S.A. Susin, N. Zamzami, K.F. Ferri, T. Irinopoulou, N. Larochette, M.C. Prevost, B. Leber, D. Andrews, J. Penninger, and G. Kroemer Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis FASEB J. 14 2000 729 739 (Pubitemid 30198571)
10. + increases mitochondrial NO and Bax protein J. Neurosci. Res. 72 2003 76 88 (Pubitemid 36373813)
11. R.C. Dodel, Y. Du, K.R. Bales, Z.D. Ling, P.M. Carvey, and S.M. Paul Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4- phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons Neuroscience 86 1998 701 707 (Pubitemid 28298729)
12. X.G. Du, W. Wang, S.P. Zhang, X.P. Pu, Q.Y. Zhang, M. Ye, Y.Y. Zhao, B.R. Wang, I.A. Khan, and D.A. Guo Neuroprotective xanthone glycosides from Swertia punicea J. Nat. Prod. 73 2010 1422 1426
13. M. Eller, and D.R. Williams Alpha-synuclein in Parkinson disease and other neurodegenerative disorders Clin. Chem. Lab. Med. 49 2011 403 408
14. P.A. Glascott Jr., E. Gilfor, and J.L. Farber Effects of vitamin E on the killing of cultured hepatocytes by tert-butyl hydroperoxide Mol. Pharmacol. 41 1992 1155 1162 (Pubitemid 23026118)
15. J.T. Greenamyre, and T.G. Hastings Biomedicine. Parkinson's - divergent causes, convergent mechanisms Science 304 2004 1120 1122 (Pubitemid 38661838)
16. L.J. Greenlund, T.L. Deckwerth, and E.M. Johnson Jr. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death Neuron 14 1995 303 315
17. N.M. Hashim, M. Rahmani, G.C. Ee, M.A. Sukari, M. Yahayu, M.A. Amin, A.M. Ali, and R. Go Antioxidant, antimicrobial and tyrosinase inhibitory activities of xanthones isolated from Artocarpus obtusus F.M. Jarrett Molecules 17 2012 6071 6082
18. +) toxicity in dopaminergic neurons Brain Res. 1197 2008 143 151
19. +) causes DNA fragmentation and increases the Bcl-2 expression in human neuroblastoma, SH-SY5Y cells, through different mechanisms Brain Res. 704 1995 240 245 (Pubitemid 26013090)
20. R. Kim, M. Emi, and K. Tanabe Role of mitochondria as the gardens of cell death Cancer Chemother. Pharmacol. 57 2006 545 553 (Pubitemid 43237837)
21. Y. Kitamura, T. Kosaka, J.I. Kakimura, Y. Matsuoka, Y. Kohno, Y. Nomura, and T. Taniguchi Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells Mol. Pharmacol. 54 1998 1046 1054 (Pubitemid 29002048)
22. L. Lalier, P.F. Cartron, P. Juin, S. Nedelkina, S. Manon, B. Bechinger, and F.M. Vallette Bax activation and mitochondrial insertion during apoptosis Apoptosis 12 2007 887 896 (Pubitemid 46653297)
23. A.E. Lang The progression of Parkinson disease: a hypothesis Neurology 68 2007 948 952 (Pubitemid 46568509)
24. Y.A. Lazebnik, S.H. Kaufmann, S. Desnoyers, G.G. Poirier, and W.C. Earnshaw Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE Nature 371 1994 346 347 (Pubitemid 24300618)
25. C. Mancuso, G. Scapagini, D. Curro, A.M. Giuffrida Stella, C. De Marco, D.A. Butterfield, and V. Calabrese Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders Front. Biosci. 12 2007 1107 1123 (Pubitemid 46846882)
26. M. Mogi, M. Harada, T. Kondo, Y. Mizuno, H. Narabayashi, P. Riederer, and T. Nagatsu bcl-2 protein is increased in the brain from parkinsonian patients Neurosci. Lett. 215 1996 137 139 (Pubitemid 26313237)
27. A. Muroyama, A. Fujita, C. Lv, S. Kobayashi, Y. Fukuyama, and Y. Mitsumoto Magnolol protects against MPTP/MPP(+)-induced toxicity via inhibition of oxidative stress in in vivo and in vitro models of Parkinson's Disease Parkinsons Dis. 2012 2012 985157
28. D. Nijhawan, N. Honarpour, and X. Wang Apoptosis in neural development and disease Annu. Rev. Neurosci. 23 2000 73 87 (Pubitemid 30350038)
29. M.S. Ola, M. Nawaz, and H. Ahsan Role of Bcl-2 family proteins and caspases in the regulation of apoptosis Mol. Cell Biochem. 351 2011 41 58
30. S. Przedborski, and H. Ischiropoulos Reactive oxygen and nitrogen species: weapons of neuronal destruction in models of Parkinson's disease Antioxid. Redox Signal. 7 2005 685 693 (Pubitemid 40563207)
31. A.H. Schapira Mitochondria in the aetiology and pathogenesis of Parkinson's disease Lancet Neurol. 7 2008 97 109 (Pubitemid 350251942)
32. J.B. Schulz Update on the pathogenesis of Parkinson's disease J. Neurol. 255 Suppl. 5 2008 3 7
33. S. Selvaraj, J.A. Watt, and B.B. Singh TRPC1 inhibits apoptotic cell degeneration induced by dopaminergic neurotoxin MPTP/MPP Cell Calcium. 46 2009 209 218
34. S.A. Susin, H.K. Lorenzo, N. Zamzami, I. Marzo, B.E. Snow, G.M. Brothers, J. Mangion, E. Jacotot, P. Costantini, M. Loeffler, N. Larochette, D.R. Goodlett, R. Aebersold, D.P. Siderovski, J.M. Penninger, and G. Kroemer Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 1999 441 446
35. P. Tan, C.Y. Hou, Y.L. Liu, L.J. Lin, and G.A. Gordell 3-O-Demethylswertipunicoside from Swertia punicea Phytochemistry 31 1992 4313 4315
36. N.A. Thornberry, and Y. Lazebnik Caspases: enemies within Science 281 1998 1312 1316 (Pubitemid 28406817)
37. K.F. Tipton, and T.P. Singer Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds J. Neurochem. 61 1993 1191 1206 (Pubitemid 23285075)
38. N. Xiong, J. Xiong, G. Khare, C. Chen, J. Huang, Y. Zhao, Z. Zhang, X. Qiao, Y. Feng, H. Reesaul, Y. Zhang, S. Sun, Z. Lin, and T. Wang Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease PLoS One 6 2011 e20677
39. S.B. Yim, S.E. Park, and C.S. Lee Protective effect of glycyrrhizin on 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death in differentiated PC12 cells J. Pharmacol. Exp. Ther. 321 2007 816 822
40. S.P. Zhang, X.G. Du, and X.P. Pu 3-O-demethylswertipunicoside protects against oxidative toxicity in PC12 cells Biol. Pharm. Bull. 33 2010 1529 1533
41. G.Y. Zhong, C.H. Wang, X. Liu, S.Y. Qin, H.R. Zhou, W.Z. Luo, R. Gu, and J.F. Zhao The resources and usage status of the commonly used Tibetan Medicinal Crop Dida World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica. 12 2010 122 128