메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

JNK3 is required for the cytoprotective effect of exendin 4

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; MITOGEN ACTIVATED PROTEIN KINASE 10; ANTIDIABETIC AGENT; INSULIN; PEPTIDE; SMALL INTERFERING RNA; VENOM;

EID: 84904210503     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2014/814854     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 33745863033 scopus 로고    scopus 로고
    • Islet β cell failure in type 2 diabetes
    • DOI 10.1172/JCI29103
    • Prentki M., Nolan C. J., Islet β cell failure in type 2 diabetes. Journal of Clinical Investigation 2006 116 7 1802 1812 2-s2.0-33745863033 10.1172/JCI29103 (Pubitemid 44033300)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 2
    • 9444242665 scopus 로고    scopus 로고
    • Five of stages of evolving β-cell dysfunction during progression to diabetes
    • DOI 10.2337/diabetes.53.suppl-3.S16
    • Weir G. C., Bonner-Weir S., Five of stages of evolving β -cell dysfunction during progression to diabetes. Diabetes 2004 53 3, supplement S16 S21 2-s2.0-9444242665 10.2337/diabetes.53.suppl-3.S16 (Pubitemid 39564517)
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Weir, G.C.1    Bonner-Weir, S.2
  • 3
    • 53549093011 scopus 로고    scopus 로고
    • Pancreatic β -cell mass in European subjects with type 2 diabetes
    • 2-s2.0-53549093011 10.1111/j.1463-1326.2008.00969.x
    • Rahier J., Guiot Y., Goebbels R. M., Sempoux C., Henquin J. C., Pancreatic β -cell mass in European subjects with type 2 diabetes. Diabetes, Obesity and Metabolism 2008 10 4, supplement 4 32 42 2-s2.0-53549093011 10.1111/j.1463-1326.2008.00969.x
    • (2008) Diabetes, Obesity and Metabolism , vol.10 , Issue.4 SUPPL. 4 , pp. 32-42
    • Rahier, J.1    Guiot, Y.2    Goebbels, R.M.3    Sempoux, C.4    Henquin, J.C.5
  • 4
    • 23644457358 scopus 로고    scopus 로고
    • β-Cell function in morbidly obese subjects during free living: Long-term effects of weight loss
    • DOI 10.2337/diabetes.54.8.2382
    • Camastra S., Manco M., Mari A., Baldi S., Gastaldelli A., Greco A. V., Mingrone G., Ferrannini E., β -cell function in morbidly obese subjects during free living: long-term effects of weight loss. Diabetes 2005 54 8 2382 2389 2-s2.0-23644457358 10.2337/diabetes.54.8.2382 (Pubitemid 41134266)
    • (2005) Diabetes , vol.54 , Issue.8 , pp. 2382-2389
    • Camastra, S.1    Manco, M.2    Mari, A.3    Baldi, S.4    Gastaldelli, A.5    Greco, A.V.6    Mingrone, G.7    Ferrannini, E.8
  • 5
    • 84894545046 scopus 로고    scopus 로고
    • β -Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice
    • Ravier M. A., Leduc M., Richard J., β -Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice. Diabetologia 2014 57 3 532 541
    • (2014) Diabetologia , vol.57 , Issue.3 , pp. 532-541
    • Ravier, M.A.1    Leduc, M.2    Richard, J.3
  • 6
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • 2-s2.0-33644618433 10.1016/j.cmet.2006.01.004
    • Drucker D. J., The biology of incretin hormones. Cell Metabolism 2006 3 3 153 165 2-s2.0-33644618433 10.1016/j.cmet.2006.01.004
    • (2006) Cell Metabolism , vol.3 , Issue.3 , pp. 153-165
    • Drucker, D.J.1
  • 7
    • 84896708385 scopus 로고    scopus 로고
    • Upregulated insulin secretion in insulin-resistant mice: Evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion
    • Ahlkvist L., Brown K., Ahren B., Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion. Endocrine Connections 2013 2 69 78
    • (2013) Endocrine Connections , vol.2 , pp. 69-78
    • Ahlkvist, L.1    Brown, K.2    Ahren, B.3
  • 9
    • 0037312821 scopus 로고    scopus 로고
    • The influence of GLP-1 on glucose-stimulated insulin secretion: Effects on β-cell sensitivity in type 2 and nondiabetic subjects
    • DOI 10.2337/diabetes.52.2.380
    • Kjems L. L., Holst J. J., Vølund A., Madsbad S., The influence of GLP-1 on glucose-stimulated insulin secretion: effects on β -cell sensitivity in type 2 and nondiabetic subjects. Diabetes 2003 52 2 380 386 2-s2.0-0037312821 10.2337/diabetes.52.2.380 (Pubitemid 36173193)
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 380-386
    • Kjems, L.L.1    Holst, J.J.2    Volund, A.3    Madsbad, S.4
  • 11
    • 79959781838 scopus 로고    scopus 로고
    • Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes
    • 2-s2.0-79959781838 10.2337/dc11-s227
    • Holst J. J., Knop F. K., Vilsbøll T., Krarup T., Madsbad S., Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes. Diabetes Care 2011 34 2, supplement S251 S257 2-s2.0-79959781838 10.2337/dc11-s227
    • (2011) Diabetes Care , vol.34 , Issue.2 SUPPL.
    • Holst, J.J.1    Knop, F.K.2    Vilsbøll, T.3    Krarup, T.4    Madsbad, S.5
  • 12
    • 34249724553 scopus 로고    scopus 로고
    • Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: Possible contribution to impaired incretin effects in diabetes
    • DOI 10.2337/db06-1033
    • Xu G., Kaneto H., Laybutt D. R., Duvivier-Kali V. F., Trivedi N., Suzuma K., King G. L., Weir G. C., Bonner-Weir S., Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes. Diabetes 2007 56 6 1551 1558 2-s2.0-34249724553 10.2337/db06-1033 (Pubitemid 46842610)
    • (2007) Diabetes , vol.56 , Issue.6 , pp. 1551-1558
    • Xu, G.1    Kaneto, H.2    Laybutt, D.R.3    Duvivier-Kali, V.F.4    Trivedi, N.5    Suzuma, K.6    King, G.L.7    Weir, G.C.8    Bonner-Weir, S.9
  • 13
    • 67249096093 scopus 로고    scopus 로고
    • Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
    • 2-s2.0-67249096093 10.1093/hmg/ddp178
    • Shu L., Matveyenko A. V., Kerr-Conte J., Cho J.-H., McIntosh C. H. S., Maedler K., Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function. Human Molecular Genetics 2009 18 13 2388 2399 2-s2.0-67249096093 10.1093/hmg/ddp178
    • (2009) Human Molecular Genetics , vol.18 , Issue.13 , pp. 2388-2399
    • Shu, L.1    Matveyenko, A.V.2    Kerr-Conte, J.3    Cho, J.-H.4    McIntosh, C.H.S.5    Maedler, K.6
  • 14
    • 0036828227 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
    • DOI 10.1210/en.2002-220405
    • Farilla L., Hongxiang H., Bertolotto C., Kang E., Bulotta A., Mario U. D. I., Perfetti R., Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 2002 143 11 4397 4408 2-s2.0-0036828227 10.1210/en.2002-220405 (Pubitemid 35239574)
    • (2002) Endocrinology , vol.143 , Issue.11 , pp. 4397-4408
    • Farilla, L.1    Hongxiang, H.2    Bertolotto, C.3    Kang, E.4    Bulotta, A.5    Mario, U.D.I.6    Perfetti, R.7
  • 15
    • 0036381989 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
    • 2-s2.0-0036381989 10.1007/s00125-002-0828-3
    • Wang Q., Brubaker P., Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice. Diabetologia 2002 45 9 1263 1273 2-s2.0-0036381989 10.1007/s00125-002-0828-3
    • (2002) Diabetologia , vol.45 , Issue.9 , pp. 1263-1273
    • Wang, Q.1    Brubaker, P.2
  • 17
    • 68049136013 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 protects β -cells against apoptosis by increasing the activity of an Igf-2/Igf-1 receptor autocrine loop
    • 2-s2.0-68049136013 10.2337/db09-0063
    • Cornu M., Yang J.-Y., Jaccard E., Poussin C., Widmann C., Thorens B., Glucagon-like peptide-1 protects β -cells against apoptosis by increasing the activity of an Igf-2/Igf-1 receptor autocrine loop. Diabetes 2009 58 8 1816 1825 2-s2.0-68049136013 10.2337/db09-0063
    • (2009) Diabetes , vol.58 , Issue.8 , pp. 1816-1825
    • Cornu, M.1    Yang, J.-Y.2    Jaccard, E.3    Poussin, C.4    Widmann, C.5    Thorens, B.6
  • 18
    • 0032768616 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)- cells
    • DOI 10.1007/s001250051238
    • Buteau J., Roduit R., Susini S., Prentki M., Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)- cells. Diabetologia 1999 42 7 856 864 2-s2.0-0032768616 10.1007/s001250051238 (Pubitemid 29325077)
    • (1999) Diabetologia , vol.42 , Issue.7 , pp. 856-864
    • Buteau, J.1    Roduit, R.2    Susini, S.3    Prentki, M.4
  • 19
    • 2542479899 scopus 로고    scopus 로고
    • Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system
    • DOI 10.1210/en.2004-0015
    • Brubaker P. L., Drucker D. J., Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology 2004 145 6 2653 2659 2-s2.0-2542479899 10.1210/en.2004-0015 (Pubitemid 38686211)
    • (2004) Endocrinology , vol.145 , Issue.6 , pp. 2653-2659
    • Brubaker, P.L.1    Drucker, D.J.2
  • 20
    • 0033513455 scopus 로고    scopus 로고
    • Exendin-4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats
    • Xu G., Stoffers D. A., Habener J. F., Bonner-Weir S., Exendin-4 stimulates both β -cell replication and neogenesis, resulting in increased β -cell mass and improved glucose tolerance in diabetic rats. Diabetes 1999 48 12 2270 2276 2-s2.0-0033513455 (Pubitemid 30395416)
    • (1999) Diabetes , vol.48 , Issue.12 , pp. 2270-2276
    • Xu, G.1    Stoffers, D.A.2    Habener, J.F.3    Bonner-Weir, S.4
  • 21
    • 77953148018 scopus 로고    scopus 로고
    • Exendin-4 prevents c-Jun N-terminal protein kinase activation by Tumor Necrosis Factor- (TNF) and inhibits TNF -induced apoptosis in insulin-secreting cells
    • 2-s2.0-77953148018 10.1210/en.2009-1166
    • Natalicchio A., de Stefano F., Orlando M. R., Melchiorre M., Leonardini A., Cignarelli A., Labarbuta R., Marchetti P., Perrini S., Laviola L., Giorgino F., Exendin-4 prevents c-Jun N-terminal protein kinase activation by Tumor Necrosis Factor- (TNF) and inhibits TNF -induced apoptosis in insulin-secreting cells. Endocrinology 2010 151 5 2019 2029 2-s2.0-77953148018 10.1210/en.2009-1166
    • (2010) Endocrinology , vol.151 , Issue.5 , pp. 2019-2029
    • Natalicchio, A.1    De Stefano, F.2    Orlando, M.R.3    Melchiorre, M.4    Leonardini, A.5    Cignarelli, A.6    Labarbuta, R.7    Marchetti, P.8    Perrini, S.9    Laviola, L.10    Giorgino, F.11
  • 22
    • 80054707772 scopus 로고    scopus 로고
    • Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets
    • 2-s2.0-80054707772 10.1007/s00125-011-2165-x
    • Favre D., Niederhauser G., Fahmi D., Plaisance V., Brajkovic S., Beeler N., Allagnat F., Haefliger J. A., Regazzi R., Waeber G., Abderrahmani A., Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets. Diabetologia 2011 54 9 2337 2346 2-s2.0-80054707772 10.1007/s00125-011-2165-x
    • (2011) Diabetologia , vol.54 , Issue.9 , pp. 2337-2346
    • Favre, D.1    Niederhauser, G.2    Fahmi, D.3    Plaisance, V.4    Brajkovic, S.5    Beeler, N.6    Allagnat, F.7    Haefliger, J.A.8    Regazzi, R.9    Waeber, G.10    Abderrahmani, A.11
  • 23
    • 23944479411 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: Role of protein kinase B
    • DOI 10.1007/s00125-005-1787-2
    • Li L., El-Kholy W., Rhodes C. J., Brubaker P. L., Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B. Diabetologia 2005 48 7 1339 1349 2-s2.0-23944479411 10.1007/s00125-005-1787-2 (Pubitemid 41186100)
    • (2005) Diabetologia , vol.48 , Issue.7 , pp. 1339-1349
    • Li, L.1    El-Kholy, W.2    Rhodes, C.J.3    Brubaker, P.L.4
  • 24
    • 33745315716 scopus 로고    scopus 로고
    • Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic β-cell mass
    • DOI 10.2337/db05-0825
    • Buteau J., Spatz M. L., Accili D., Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic β -cell mass. Diabetes 2006 55 5 1190 1196 2-s2.0-33745315716 10.2337/db05-0825 (Pubitemid 44195354)
    • (2006) Diabetes , vol.55 , Issue.5 , pp. 1190-1196
    • Buteau, J.1    Spatz, M.L.2    Accili, D.3
  • 25
    • 33750448469 scopus 로고    scopus 로고
    • GLP-1 receptor activation improves β cell function and survival following induction of endoplasmic reticulum stress
    • DOI 10.1016/j.cmet.2006.10.001, PII S1550413106003299
    • Yusta B., Baggio L. L., Estall J. L., Koehler J. A., Holland D. P., Li H., Pipeleers D., Ling Z., Drucker D. J., GLP-1 receptor activation improves β cell function and survival following induction of endoplasmic reticulum stress. Cell Metabolism 2006 4 5 391 406 2-s2.0-33750448469 10.1016/j.cmet.2006. 10.001 (Pubitemid 44752565)
    • (2006) Cell Metabolism , vol.4 , Issue.5 , pp. 391-406
    • Yusta, B.1    Baggio, L.L.2    Estall, J.L.3    Koehler, J.A.4    Holland, D.P.5    Li, H.6    Pipeleers, D.7    Ling, Z.8    Drucker, D.J.9
  • 26
    • 80053524655 scopus 로고    scopus 로고
    • Roles and regulation of the transcription factor CREB in pancreatic β -cells
    • 2-s2.0-80053524655 10.2174/1874467211104030187
    • Dalle S., Quoyer J., Varin E., Costes S., Roles and regulation of the transcription factor CREB in pancreatic β -cells. Current Molecular Pharmacology 2011 4 3 187 195 2-s2.0-80053524655 10.2174/1874467211104030187
    • (2011) Current Molecular Pharmacology , vol.4 , Issue.3 , pp. 187-195
    • Dalle, S.1    Quoyer, J.2    Varin, E.3    Costes, S.4
  • 27
    • 33644850386 scopus 로고    scopus 로고
    • Exendin-4 uses Irs2 signaling to mediate pancreatic β cell growth and function
    • 2-s2.0-33644850386 10.1074/jbc.M508307200
    • Park S., Dong X., Fisher T. L., Dunn S., Omer A. K., Weir G., White M. F., Exendin-4 uses Irs2 signaling to mediate pancreatic β cell growth and function. Journal of Biological Chemistry 2006 281 2 1159 1168 2-s2.0-33644850386 10.1074/jbc.M508307200
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.2 , pp. 1159-1168
    • Park, S.1    Dong, X.2    Fisher, T.L.3    Dunn, S.4    Omer, A.K.5    Weir, G.6    White, M.F.7
  • 28
    • 33644859688 scopus 로고    scopus 로고
    • ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis
    • DOI 10.1038/sj.emboj.7601008, PII 7601008
    • Abderrahmani A., Cheviet S., Ferdaoussi M., Coppola T., Waeber G., Regazzi R., ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis. EMBO Journal 2006 25 5 977 986 2-s2.0-33644859688 10.1038/sj.emboj.7601008 (Pubitemid 43372112)
    • (2006) EMBO Journal , vol.25 , Issue.5 , pp. 977-986
    • Abderrahmani, A.1    Cheviet, S.2    Ferdaoussi, M.3    Coppola, T.4    Waeber, G.5    Regazzi, R.6
  • 29
    • 84860488011 scopus 로고    scopus 로고
    • JNK3 maintains expression of the insulin receptor substrate 2 (IRS2) in insulin-secreting cells: Functional consequences for insulin signaling
    • 2-s2.0-84860488011 10.1371/journal.pone.0035997 e35997
    • Abdelli S., Bonny C., JNK3 maintains expression of the insulin receptor substrate 2 (IRS2) in insulin-secreting cells: functional consequences for insulin signaling. PLoS ONE 2012 7 5 2-s2.0-84860488011 10.1371/journal.pone. 0035997 e35997
    • (2012) PLoS ONE , vol.7 , Issue.5
    • Abdelli, S.1    Bonny, C.2
  • 30
    • 68449084306 scopus 로고    scopus 로고
    • JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis
    • 2-s2.0-68449084306 10.1007/s00125-009-1431-7
    • Abdelli S., Puyal J., Bielmann C., Buchillier V., Abderrahmani A., Clarke P. G. H., Beckmann J. S., Bonny C., JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis. Diabetologia 2009 52 9 1871 1880 2-s2.0-68449084306 10.1007/s00125-009-1431-7
    • (2009) Diabetologia , vol.52 , Issue.9 , pp. 1871-1880
    • Abdelli, S.1    Puyal, J.2    Bielmann, C.3    Buchillier, V.4    Abderrahmani, A.5    Clarke, P.G.H.6    Beckmann, J.S.7    Bonny, C.8
  • 31
    • 48449104756 scopus 로고    scopus 로고
    • Exendin-4 protects β -cells from interleukin-1 β -induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway
    • 2-s2.0-48449104756 10.2337/db07-1214
    • Ferdaoussi M., Abdelli S., Yang J.-Y., Cornu M., Niederhauser G., Favre D., Widmann C., Regazzi R., Thorens B., Waeber G., Abderrahmani A., Exendin-4 protects β -cells from interleukin-1 β -induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway. Diabetes 2008 57 5 1205 1215 2-s2.0-48449104756 10.2337/db07-1214
    • (2008) Diabetes , vol.57 , Issue.5 , pp. 1205-1215
    • Ferdaoussi, M.1    Abdelli, S.2    Yang, J.-Y.3    Cornu, M.4    Niederhauser, G.5    Favre, D.6    Widmann, C.7    Regazzi, R.8    Thorens, B.9    Waeber, G.10    Abderrahmani, A.11
  • 33
    • 78649489519 scopus 로고    scopus 로고
    • Exendin-4 protects murine pancreatic β -cells from dexamethasone-induced apoptosis through PKA and PI-3K signaling
    • 2-s2.0-78649489519 10.1016/j.diabres.2010.09.004
    • Wang L.-X., Wang Y.-P., Chen Z., Liu X.-Y., Liu X.-H., Liu L., Chen W.-J., Liu L.-B., Exendin-4 protects murine pancreatic β -cells from dexamethasone-induced apoptosis through PKA and PI-3K signaling. Diabetes Research and Clinical Practice 2010 90 3 297 304 2-s2.0-78649489519 10.1016/j.diabres.2010.09.004
    • (2010) Diabetes Research and Clinical Practice , vol.90 , Issue.3 , pp. 297-304
    • Wang, L.-X.1    Wang, Y.-P.2    Chen, Z.3    Liu, X.-Y.4    Liu, X.-H.5    Liu, L.6    Chen, W.-J.7    Liu, L.-B.8
  • 34
    • 84901851345 scopus 로고    scopus 로고
    • Of rodents and men: Species-specific glucose regulation and type 2 diabetes research
    • Chandrasekera P. C., Pippin J. J., Of rodents and men: species-specific glucose regulation and type 2 diabetes research. Altex 2014 31 157 176
    • (2014) Altex , vol.31 , pp. 157-176
    • Chandrasekera, P.C.1    Pippin, J.J.2
  • 35
    • 84903158684 scopus 로고    scopus 로고
    • RFamide peptides 43RFa and 26RFa both promote survival of pancreatic beta-cells and human pancreatic islets but exert opposite effects on insulin secretion
    • Granata R., Settanni F., Trovato L., RFamide peptides 43RFa and 26RFa both promote survival of pancreatic beta-cells and human pancreatic islets but exert opposite effects on insulin secretion. Diabetes 2014
    • (2014) Diabetes
    • Granata, R.1    Settanni, F.2    Trovato, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.