Multifunctional, self-assembling anionic peptide-lipid nanocomplexes for targeted siRNA delivery

Biomaterials

Volumn 35, Issue 29, 2014, Pages 8406-8415

  Tagalakis, Aristides D ^a   Lee, Do Hyang D ^a   Bienemann, Alison S ^b   Zhou, Haiyan ^a   Munye, Mustafa M ^a   Saraiva, Luisa ^a   McCarthy, David ^c   Du, Zixiu ^a   Vink, Conrad A ^a   Maeshima, Ruhina ^a   White, Edward A ^b   Gustafsson, Kenth ^a   Hart, Stephen L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Anionic liposome; Gene silencing; Gene therapy; Nanoparticle; SiRNA; Targeted

Indexed keywords

BODY FLUIDS; GENE THERAPY; GENETIC ENGINEERING; LIPOSOMES; PEPTIDES; POLYMERASE CHAIN REACTION; RNA;

ANIONIC LIPOSOMES; CATIONIC NANOPARTICLES; CONVECTION-ENHANCED DELIVERY; GENE SILENCING; SIRNA; TARGETED; TRANSFECTION EFFICIENCY; WESTERN-BLOT ANALYSIS;

NANOPARTICLES;

ANION; BETA SECRETASE 1; LIPOSOME; LYSINE DERIVATIVE; NANOPARTICLE; SMALL INTERFERING RNA; ASPARTIC PROTEINASE; BACE PROTEIN, RAT; LIPID; MACROGOL DERIVATIVE; SECRETASE;

ADULT; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; LIPOSOMAL GENE DELIVERY SYSTEM; MALE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; RAT; ZETA POTENTIAL; ANIMAL; BRAIN; BRAIN DISEASES; CELL LINE; CHEMISTRY; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; METABOLISM; PROCEDURES; RNA INTERFERENCE; WISTAR RAT;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANIONS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; BRAIN DISEASES; CELL LINE; GENETIC THERAPY; HUMANS; LIPIDS; LIPOSOMES; MALE; NANOPARTICLES; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84904136193     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.06.003     Document Type: Article

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