The impact of microRNA expression on cellular proliferation

Human Genetics

Volumn 133, Issue 7, 2014, Pages 931-938

  Lenkala, Divya ^a   LaCroix, Bonnie ^a   Gamazon, Eric R ^a   Geeleher, Paul ^a   Im, Hae Kyung ^a   Huang, R Stephanie ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 22; UNTRANSLATED RNA;

ARTICLE; CANCER INHIBITION; CAUCASIAN; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MXI1 GENE; NIGERIA; NUCLEOTIDE SEQUENCE; ONCOGENE; OVARIAN CANCER CELL LINE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SLC25A37 GENE; WESTERN EUROPE;

AFRICAN CONTINENTAL ANCESTRY GROUP; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CATION TRANSPORT PROTEINS; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL PROLIFERATION; ETHNIC GROUPS; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME-WIDE ASSOCIATION STUDY; HAPMAP PROJECT; HUMANS; MICRORNAS; MITOCHONDRIAL PROTEINS; NIGERIA; OVARIAN NEOPLASMS; PHENOTYPE; REGRESSION ANALYSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 84904118591     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-014-1434-4     Document Type: Article

References (53)

1. Bar N, Dikstein R (2010) miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics. PLoS One 5:e10859
2. Bartel DP (2009) MicroRNA s: target recognition and regulatory functions. Cell 136:215-233
3. Chen W, Paradkar PN, Li L, Pierce EL, Langer NB, Takahashi-Makise N, Hyde BB, Shirihai OS, Ward DM, Kaplan J et al (2009) Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proc Natl Acad Sci USA 106:16263-16268
4. Dang Y, Luo D, Rong M, Chen G (2013) Underexpression of miR-34a in hepatocellular carcinoma and its contribution towards enhancement of proliferating inhibitory effects of agents targeting c-MET. PLoS One 8:e61054
5. Duan S, Huang RS, Zhang W, Bleibel WK, Roe CA, Clark TA, Chen TX, Schweitzer AC, Blume JE, Cox NJ et al (2008) Genetic architecture of transcript-level variation in humans. Am J Hum Genet 82:1101-1113
6. Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve L, Gibbs RA, Belmont JW, Boudreau A, Hardenbol P, Leal SM et al (2007) A second generation** human haplotype map of over 3.1 million SNPs. Nature 449:851-861 (Pubitemid 47598626)
7. Fonseca-Sanchéz MA, Pérez-Plasencia C, Fernández- Retana J, Arechaga-Ocampo E, Marchat LA, Rodríguez-Cuevas S, Bautista-Piña V, Arellano-Anaya ZE, Flores-Pérez A, Diaz-Chávez J et al (2013) microRNA-18b is upregulated in breast cancer and modulates genes involved in cell migration. Oncol Rep 30:2399-2410
8. Gamazon ER, Ziliak D, Im HK, LaCroix B, Park DS, Cox NJ, Huang RS (2012) Genetic architecture of microRNA expression: implications for the transcriptome and complex traits. Am J Hum Genet 90:1046-1063
9. González-Gugel E, Villa-Morales M, Santos J, Bueno MJ, Malumbres M, Rodríguez-Pinilla SM, Piris MÁ, Fernández-Piqueras J (2013) Down-regulation of specific miRNA s enhances the expression of the gene smoothened and contributes to T-cell lymphoblastic lymphoma development. Carcinogenesis 34(4):902-908
10. He J, Wu J, Xu N, Xie W, Li M, Li J, Jiang Y, Yang BB, Zhang Y (2012) MiR-210 disturbs mitotic progression through regulating a group of mitosis-related genes. Nucleic Acids Res 41(1):498-508. doi:10.1093/nar/gks995
11. Hsiao C-P, Wang D, Kaushal A, Saligan L (2013) Mitochondria-related gene expression changes are associated with fatigue in patients with nonmetastatic prostate cancer receiving external beam radiation therapy. Cancer Nurs 36(3):189-197
12. Huang RS, Kistner EO, Bleibel WK, Shukla SJ, Dolan ME (2007) Effect of population and gender on chemotherapeutic agent-induced cytotoxicity. Mol Cancer Ther 6:31-36 (Pubitemid 46206666)
13. Hurlin PJ, Dezfouli S (2004) Functions of myc:max in the control of cell proliferation and tumorigenesis. Int Rev Cytol 238:183-226 (Pubitemid 39201316)
14. Huang Z-P, Chen J, Seok HY, Zhang Z, Kataoka M, Hu X, Wang D-Z (2013) MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circ Res 112:1234-1243
15. Huang DW, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4:44-57
16. Hwang H-W, Mendell JT (2006) MicroRNA s in cell proliferation, cell death, and tumorigenesis. Br J Cancer 94:776-780
17. Im HK, Gamazon ER, Stark AL, Huang RS, Cox NJ, Dolan ME (2012) Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer. PLoS Genet 8:e1002525
18. Imam JS, Buddavarapu K, Lee-Chang JS, Ganapathy S, Camosy C, Chen Y, Rao MK (2010) MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers. Oncogene 29:4971-4979
19. Kashat M, Azzouz L, Sarkar SH, Kong D, Li Y, Sarkar FH (2012) Inactivation of AR and Notch-1 signaling by miR-34a attenuates prostate cancer aggressiveness. Am J Transl Res 4:432-442
20. Kaur K, Pandey AK, Srivastava S, Srivastava AK, Datta M (2011) Comprehensive miRNome and in silico analyses identify the Wnt signaling pathway to be altered in the diabetic liver. Mol Biosyst 7:3234-3244
21. Lal A, Thomas MP, Altschuler G, Navarro F, O'Day E, Li XL, Concepcion C, Han Y-C, Thiery J, Rajani DK et al (2011) Capture of microRNA-bound mRNA s identifies the tumor suppressor miR-34a as a regulator of growth factor signaling. PLoS Genet 7:e1002363
22. Li X-F, Yan P-J, Shao Z-M (2009) Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer. Oncogene 28:3937-3948
23. Li J, Liang S, Yu H, Zhang J, Ma D, Lu X (2010) An inhibitory effect of miR-22 on cell migration and invasion in ovarian cancer. Gynecol Oncol 119:543-548
24. Liu L, Jiang Y, Zhang H, Greenlee AR, Yu R, Yang Q (2010) miR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide. Toxicol In Vitr 24:1168-1175
25. Morris KV, Chan SW-L, Jacobsen SE, Looney DJ (2004) Small interfering RNA-induced transcriptional gene silencing in human cells. Science 305:1289-1292
26. Pandey DP, Picard D (2009) miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor α mRNA . Mol Cell Biol 29:3783-3790
27. Pickrell JK, Marioni JC, Pai A, Degner JF, Engelhardt BE, Nkadori E, Veyrieras J-B, Stephens M, Gilad Y, Pritchard JK (2010) Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature 464:768-772
28. Puisségur M-P, Mazure NM, Bertero T, Pradelli L, Grosso S, Robbe-Sermesant K, Maurin T, Lebrigand K, Cardinaud B, Hofman V et al (2011) miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity. Cell Death Differ 18:465-478
29. Qi J, Rice SJ, Salzberg AC, Runkle EA, Liao J, Zander DS, Mu D (2012) MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1. Cell Cycle 11:177-186
30. Ramberg H, Alshbib A, Berge V, Svindland A, Taskén KA (2011) Regulation of PBX3 expression by androgen and Let-7d in prostate cancer. Mol Cancer 10:50
31. Schafer KA (1998) The cell cycle: a review. Vet Pathol 35:461-478
32. Song Y-X, Yue Z-Y, Wang Z-N, Xu Y-Y, Luo Y, Xu H-M, Zhang X, Jiang L, Xing C-Z, Zhang Y (2011a) MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation. Mol Cancer 10:1
33. Song Y, Xu Y, Wang Z, Chen Y, Yue Z, Gao P, Xing C, Xu H (2011b) MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer. Int J Cancer 1051:1042-1051
34. Stranger BE, Nica AC, Forrest MS, Dimas A, Bird CP, Beazley C, Ingle CE, Dunning M, Flicek P, Koller D et al (2007) Population genomics of human gene expression. Nat Genet 39:1217-1224 (Pubitemid 47482691)
35. Stark AL, Zhang W, Mi S, Duan S, O'Donnell PH, Huang RS, Dolan ME (2010) Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines. Pharmacogenomics J 10:505-512
36. Storey JD, Tibshirani R (2003) Statistical significance for genome-wide studies. Proc Natl Acad Sci USA 100:9440-9445
37. Suzuki HI, Miyazono K (2011) Emerging complexity of microRNA generation cascades. J Biochem 149:15-25
38. Takata A, Otsuka M, Kojima K, Yoshikawa T, Kishikawa T, Yoshida H, Koike K (2011) MicroRNA-22 and microRNA-140 suppress NF-κB activity by regulating the expression of NF-κB coactivators. Biochem Biophys Res Commun 411:826-831
39. The 1000 Genomes Project Consortium (2010) A map of human genome variation from population-scale sequencing. Nature 467:1061-1073
40. Ting Y, Medina DJ, Strair RK, Schaar DG (2010) Differentiation-associated miR-22 represses Max expression and inhibits cell cycle progression. Biochem Biophys Res Commun 394:606-611
41. Tsoi M, Laguë M-N, Boyer A, Paquet M, Nadeau M-È, Boerboom D (2013) Anti-VEGFA therapy reduces tumor growth and extends survival in a murine model of ovarian granulosa cell tumor. Transl Oncol 6:226-233
42. Tsuchiya N, Izumiya M, Ogata-Kawata H, Okamoto K, Fujiwara Y, Nakai M, Okabe A, Schetter AJ, Bowman ED, Midorikawa Y et al (2011) Tumor suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p21. Cancer Res 71:4628-4639
43. Whitfield ML, George LK, Grant GD, Perou CM (2006) Common markers of proliferation. Nat Rev Cancer 6:99-106 (Pubitemid 43361542)
44. Xiong J, Yu D, Wei N, Fu H, Cai T, Huang Y, Wu C, Zheng X, Du Q, Lin D et al (2010a) An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples. FEBS J 277:1684-1694
45. Xiong J, Du Q, Liang Z (2010b) Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein. Oncogene 29:4980-4988
46. Xu D, Takeshita F, Hino Y, Fukunaga S, Kudo Y, Tamaki A, Matsunaga J, Takahashi R-U, Takata T, Shimamoto A et al (2011) miR-22 represses cancer progression by inducing cellular senescence. J Cell Biol 193:409-424
47. Yamakuchi M, Yagi S, Ito T, Lowenstein CJ (2011) MicroRNA-22 regulates hypoxia signaling in colon cancer cells. PLoS One 6:e20291
48. Yu T, Wang X, Gong R, Li A, Yang S, Cao Y, Wen Y, Wang C, Yi X (2009) The expression profile of microRNA s in a model of 7,12-dimethyl-benz[a]anthrance- induced oral carcinogenesis in Syrian hamster. J Exp Clin Cancer Res 28:64
49. Zervos AS, Gyuris J, Brent R (1993) Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell 72:223-232 (Pubitemid 23044937)
50. Zhao C, Sun G, Ye P, Li S, Shi Y (2013) MicroRNA let-7d regulates the TLX/microRNA-9 cascade to control neural cell fate and neurogenesis. Sci Rep 3:1329
51. Zhang J, Yang Y, Yang T, Liu Y, Li A, Fu S, Wu M, Pan Z, Zhou W (2010) microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity. Br J Cancer 103:1215-1220
52. Zhang W, Duan S, Kistner EO, Bleibel WK, Huang RS, Clark TA, Chen TX, Schweitzer AC, Blume JE, Cox NJ et al (2008) Evaluation of genetic variation contributing to differences in gene expression between populations. Am J Hum Genet 82:631-640
53. Zheng Z-F, Su H-F, Zou Y, Peng Z, Wu S-X (2011) Expression profiles of microRNA s in radioresistant esophageal cell line. Zhonghua Yi Xue Za Zhi 91:639-642