Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling

PLoS Genetics

Volumn 7, Issue 11, 2011, Pages

  Lal, Ashish ^a,b,c   Thomas, Marshall P ^a,b   Altschuler, Gabriel ^d   Navarro, Francisco ^a,b   O'Day, Elizabeth ^a,b   Li, Xiao Ling ^c   Concepcion, Carla ^e   Han, Yoon Chi ^e   Thiery, Jerome ^a,b   Rajani, Danielle K ^a,b   Deutsch, Aaron ^a,b   Hofmann, Oliver ^d   Ventura, Andrea ^e   Hide, Winston ^d   Lieberman, Judy ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARAF PROTEIN; CYCLIN D3; CYCLIN G2; GROWTH FACTOR; MICRORNA; MICRORNA 34A; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 5; MITOGEN ACTIVATED PROTEIN KINASE; PIK3R2 PROTEIN; POLO LIKE KINASE 1; PROTEIN KINASE B; RAF PROTEIN; RAS PROTEIN; SIGNAL PEPTIDE; SMAD4 PROTEIN; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; MESSENGER RNA; MIRN34 MICRORNA, HUMAN; ONCOPROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE PROGRESSION; CELL DIVISION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; CELL PROLIFERATION; CELL STRAIN HCT116; CELL STRAIN K 562; DNA MICROARRAY; GENE REGULATORY NETWORK; GENETICS; HELA CELL; METABOLISM; PHOSPHORYLATION;

CELL CYCLE PROTEINS; CELL DIVISION; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENES, TUMOR SUPPRESSOR; HCT116 CELLS; HELA CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; K562 CELLS; MAP KINASE SIGNALING SYSTEM; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 81755163085     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002363     Document Type: Article

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