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Volumn 90, Issue 6, 2012, Pages 1046-1063

Genetic architecture of microRNA expression: Implications for the transcriptome and complex traits

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; MESSENGER RNA; MICRORNA; TRANSCRIPTOME;

EID: 84862114807     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2012.04.023     Document Type: Article
Times cited : (82)

References (71)
  • 2
    • 13444306165 scopus 로고    scopus 로고
    • The landscape of genetic complexity across 5,700 gene expression traits in yeast
    • R.B. Brem, and L. Kruglyak The landscape of genetic complexity across 5,700 gene expression traits in yeast Proc. Natl. Acad. Sci. USA 102 2005 1572 1577
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 1572-1577
    • Brem, R.B.1    Kruglyak, L.2
  • 3
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
    • E. Huntzinger, and E. Izaurralde Gene silencing by microRNAs: Contributions of translational repression and mRNA decay Nat. Rev. Genet. 12 2011 99 110
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 4
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • A.P. Bird CpG-rich islands and the function of DNA methylation Nature 321 1986 209 213
    • (1986) Nature , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 6
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • International HapMap Consortium
    • International HapMap Consortium The International HapMap Project Nature 426 2003 789 796
    • (2003) Nature , vol.426 , pp. 789-796
  • 7
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • 1000 Genomes Project Consortium
    • 1000 Genomes Project Consortium A map of human genome variation from population-scale sequencing Nature 467 2010 1061 1073
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 9
    • 79952194317 scopus 로고    scopus 로고
    • Discovery and genotyping of genome structural polymorphism by sequencing on a population scale
    • R.E. Handsaker, J.M. Korn, J. Nemesh, and S.A. McCarroll Discovery and genotyping of genome structural polymorphism by sequencing on a population scale Nat. Genet. 43 2011 269 276
    • (2011) Nat. Genet. , vol.43 , pp. 269-276
    • Handsaker, R.E.1    Korn, J.M.2    Nemesh, J.3    McCarroll, S.A.4
  • 15
    • 54049083902 scopus 로고    scopus 로고
    • Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans
    • R.S. Huang, S. Duan, E.O. Kistner, C.M. Hartford, and M.E. Dolan Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans Mol. Cancer Ther. 7 2008 3038 3046
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3038-3046
    • Huang, R.S.1    Duan, S.2    Kistner, E.O.3    Hartford, C.M.4    Dolan, M.E.5
  • 18
    • 77957153139 scopus 로고    scopus 로고
    • Small RNAs are on the move
    • D.H. Chitwood, and M.C. Timmermans Small RNAs are on the move Nature 467 2010 415 419
    • (2010) Nature , vol.467 , pp. 415-419
    • Chitwood, D.H.1    Timmermans, M.C.2
  • 19
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression
    • J.G. Doench, and P.A. Sharp Specificity of microRNA target selection in translational repression Genes Dev. 18 2004 504 511
    • (2004) Genes Dev. , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 25
    • 84859185340 scopus 로고    scopus 로고
    • Mixed effects modeling of proliferation rates in cell-based models: Consequence for pharmacogenomics and cancer
    • H.K. Im, E.R. Gamazon, A.L. Stark, R.S. Huang, N.J. Cox, and M.E. Dolan Mixed effects modeling of proliferation rates in cell-based models: Consequence for pharmacogenomics and cancer PLoS Genet. 8 2012 e1002525
    • (2012) PLoS Genet. , vol.8 , pp. 1002525
    • Im, H.K.1    Gamazon, E.R.2    Stark, A.L.3    Huang, R.S.4    Cox, N.J.5    Dolan, M.E.6
  • 26
    • 78649334770 scopus 로고    scopus 로고
    • Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines
    • A.L. Stark, W. Zhang, S. Mi, S. Duan, P.H. O'Donnell, R.S. Huang, and M.E. Dolan Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines Pharmacogenomics J. 10 2010 505 512
    • (2010) Pharmacogenomics J. , vol.10 , pp. 505-512
    • Stark, A.L.1    Zhang, W.2    Mi, S.3    Duan, S.4    O'Donnell, P.H.5    Huang, R.S.6    Dolan, M.E.7
  • 27
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • J.D. Storey, and R. Tibshirani Statistical significance for genomewide studies Proc. Natl. Acad. Sci. USA 100 2003 9440 9445
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 30
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • R.C. Friedman, K.K. Farh, C.B. Burge, and D.P. Bartel Most mammalian mRNAs are conserved targets of microRNAs Genome Res. 19 2009 92 105
    • (2009) Genome Res. , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 32
    • 33846118697 scopus 로고    scopus 로고
    • PolymiRTS Database: Linking polymorphisms in microRNA target sites with complex traits
    • L. Bao, M. Zhou, L. Wu, L. Lu, D. Goldowitz, R.W. Williams, and Y. Cui PolymiRTS Database: Linking polymorphisms in microRNA target sites with complex traits Nucleic Acids Res. 35 Database issue 2007 D51 D54
    • (2007) Nucleic Acids Res. , vol.35 , Issue.DATABASE ISSUE
    • Bao, L.1    Zhou, M.2    Wu, L.3    Lu, L.4    Goldowitz, D.5    Williams, R.W.6    Cui, Y.7
  • 33
    • 75549088251 scopus 로고    scopus 로고
    • Patrocles: A database of polymorphic miRNA-mediated gene regulation in vertebrates
    • S. Hiard, C. Charlier, W. Coppieters, M. Georges, and D. Baurain Patrocles: A database of polymorphic miRNA-mediated gene regulation in vertebrates Nucleic Acids Res. 38 Database issue 2010 D640 D651
    • (2010) Nucleic Acids Res. , vol.38 , Issue.DATABASE ISSUE
    • Hiard, S.1    Charlier, C.2    Coppieters, W.3    Georges, M.4    Baurain, D.5
  • 34
    • 77951439152 scopus 로고    scopus 로고
    • Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
    • D.L. Nicolae, E. Gamazon, W. Zhang, S. Duan, M.E. Dolan, and N.J. Cox Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS PLoS Genet. 6 2010 e1000888
    • (2010) PLoS Genet. , vol.6 , pp. 1000888
    • Nicolae, D.L.1    Gamazon, E.2    Zhang, W.3    Duan, S.4    Dolan, M.E.5    Cox, N.J.6
  • 36
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • W. Huang, B.T. Sherman, and R.A. Lempicki Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat. Protoc. 4 2009 44 57
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 37
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • W. Huang, B.T. Sherman, and R.A. Lempicki Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists Nucleic Acids Res. 37 2009 1 13
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1-13
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 38
    • 77952918274 scopus 로고    scopus 로고
    • Genetic variation in microRNA networks: The implications for cancer research
    • B.M. Ryan, A.I. Robles, and C.C. Harris Genetic variation in microRNA networks: The implications for cancer research Nat. Rev. Cancer 10 2010 389 402
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 389-402
    • Ryan, B.M.1    Robles, A.I.2    Harris, C.C.3
  • 40
    • 84855171610 scopus 로고    scopus 로고
    • The Influence of 3′UTRs on MicroRNA Function Inferred from Human SNP Data
    • Z. Hu, and A.E. Bruno The Influence of 3′UTRs on MicroRNA Function Inferred from Human SNP Data Comp. Funct. Genomics 2011 2011 910769
    • (2011) Comp. Funct. Genomics , vol.2011 , pp. 910769
    • Hu, Z.1    Bruno, A.E.2
  • 41
    • 80053901650 scopus 로고    scopus 로고
    • A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS
    • K. Richardson, C.-Q. Lai, L.D. Parnell, Y.-C. Lee, and J.M. Ordovas A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS BMC Genomics 12 2011 504
    • (2011) BMC Genomics , vol.12 , pp. 504
    • Richardson, K.1    Lai, C.-Q.2    Parnell, L.D.3    Lee, Y.-C.4    Ordovas, J.M.5
  • 42
    • 80052476453 scopus 로고    scopus 로고
    • Inferring causative variants in microRNA target sites
    • L.F. Thomas, T. Saito, and P. Sætrom Inferring causative variants in microRNA target sites Nucleic Acids Res. 39 2011 e109
    • (2011) Nucleic Acids Res. , vol.39 , pp. 109
    • Thomas, L.F.1    Saito, T.2    Sætrom, P.3
  • 44
    • 0034265993 scopus 로고    scopus 로고
    • Mapping of the human genes (SLC23A2 and SLC23A1) coding for vitamin C transporters 1 and 2 (SVCT1 and SVCT2) to 5q23 and 20p12, respectively
    • C.A. Stratakis, S.E. Taymans, R. Daruwala, J. Song, and M. Levine Mapping of the human genes (SLC23A2 and SLC23A1) coding for vitamin C transporters 1 and 2 (SVCT1 and SVCT2) to 5q23 and 20p12, respectively J. Med. Genet. 37 2000 E20
    • (2000) J. Med. Genet. , vol.37 , pp. 20
    • Stratakis, C.A.1    Taymans, S.E.2    Daruwala, R.3    Song, J.4    Levine, M.5
  • 47
    • 51849117309 scopus 로고    scopus 로고
    • Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma
    • H.C. Erichsen, U. Peters, P. Eck, R. Welch, R.E. Schoen, M. Yeager, M. Levine, R.B. Hayes, and S. Chanock Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma Nutr. Cancer 60 2008 652 659
    • (2008) Nutr. Cancer , vol.60 , pp. 652-659
    • Erichsen, H.C.1    Peters, U.2    Eck, P.3    Welch, R.4    Schoen, R.E.5    Yeager, M.6    Levine, M.7    Hayes, R.B.8    Chanock, S.9
  • 50
    • 84857691987 scopus 로고    scopus 로고
    • Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis
    • Published online November 23, 2011
    • J. Gong, Y. Tong, H.M. Zhang, K. Wang, T. Hu, G. Shan, J. Sun, and A.Y. Guo Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis Hum. Mutat. 33 2012 254 263 Published online November 23, 2011
    • (2012) Hum. Mutat. , vol.33 , pp. 254-263
    • Gong, J.1    Tong, Y.2    Zhang, H.M.3    Wang, K.4    Hu, T.5    Shan, G.6    Sun, J.7    Guo, A.Y.8
  • 52
    • 18244408825 scopus 로고    scopus 로고
    • A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia
    • H.C. Kuo, C.F. Cheng, R.B. Clark, J.J. Lin, J.L. Lin, M. Hoshijima, V.T. Nguyêñ-Trân, Y. Gu, Y. Ikeda, and P.H. Chu A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia Cell 107 2001 801 813
    • (2001) Cell , vol.107 , pp. 801-813
    • Kuo, H.C.1    Cheng, C.F.2    Clark, R.B.3    Lin, J.J.4    Lin, J.L.5    Hoshijima, M.6    Nguyêñ-Trân, V.T.7    Gu, Y.8    Ikeda, Y.9    Chu, P.H.10
  • 53
    • 74049096307 scopus 로고    scopus 로고
    • MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts
    • S.J. Matkovich, W. Wang, Y. Tu, W.H. Eschenbacher, L.E. Dorn, G. Condorelli, A. Diwan, J.M. Nerbonne, and G.W. Dorn 2nd MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts Circ. Res. 106 2010 166 175
    • (2010) Circ. Res. , vol.106 , pp. 166-175
    • Matkovich, S.J.1    Wang, W.2    Tu, Y.3    Eschenbacher, W.H.4    Dorn, L.E.5    Condorelli, G.6    Diwan, A.7    Nerbonne, J.M.8    Dorn II, G.W.9
  • 54
    • 33847038668 scopus 로고    scopus 로고
    • MicroRNAs play an essential role in the development of cardiac hypertrophy
    • D. Sayed, C. Hong, I.Y. Chen, J. Lypowy, and M. Abdellatif MicroRNAs play an essential role in the development of cardiac hypertrophy Circ. Res. 100 2007 416 424
    • (2007) Circ. Res. , vol.100 , pp. 416-424
    • Sayed, D.1    Hong, C.2    Chen, I.Y.3    Lypowy, J.4    Abdellatif, M.5
  • 55
    • 79957626588 scopus 로고    scopus 로고
    • MicroRNA-378 targets the myogenic repressor MyoR during myoblast differentiation
    • J. Gagan, B.K. Dey, R. Layer, Z. Yan, and A. Dutta MicroRNA-378 targets the myogenic repressor MyoR during myoblast differentiation J. Biol. Chem. 286 2011 19431 19438
    • (2011) J. Biol. Chem. , vol.286 , pp. 19431-19438
    • Gagan, J.1    Dey, B.K.2    Layer, R.3    Yan, Z.4    Dutta, A.5
  • 56
    • 20444480933 scopus 로고    scopus 로고
    • Modulation of cholinephosphotransferase activity in breast cancer cell lines by Ro5-4864, a peripheral benzodiazepine receptor agonist
    • J. Akech, S. Sinha Roy, and S.K. Das Modulation of cholinephosphotransferase activity in breast cancer cell lines by Ro5-4864, a peripheral benzodiazepine receptor agonist Biochem. Biophys. Res. Commun. 333 2005 35 41
    • (2005) Biochem. Biophys. Res. Commun. , vol.333 , pp. 35-41
    • Akech, J.1    Sinha Roy, S.2    Das, S.K.3
  • 61
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines
    • B.D. Adams, H. Furneaux, and B.A. White The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines Mol. Endocrinol. 21 2007 1132 1147
    • (2007) Mol. Endocrinol. , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 62
    • 77951964981 scopus 로고    scopus 로고
    • Posttranscriptional regulation of microRNA biogenesis in animals
    • H. Siomi, and M.C. Siomi Posttranscriptional regulation of microRNA biogenesis in animals Mol. Cell 38 2010 323 332
    • (2010) Mol. Cell , vol.38 , pp. 323-332
    • Siomi, H.1    Siomi, M.C.2
  • 63
    • 66449123316 scopus 로고    scopus 로고
    • The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins
    • D. Lazzaretti, I. Tournier, and E. Izaurralde The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins RNA 15 2009 1059 1066
    • (2009) RNA , vol.15 , pp. 1059-1066
    • Lazzaretti, D.1    Tournier, I.2    Izaurralde, E.3
  • 64
    • 70349771038 scopus 로고    scopus 로고
    • Genomewide association study for onset age in Parkinson disease
    • PROGENI Investigators, Coordinators and Molecular Genetic Laboratories GenePD Investigators, Coordinators and Molecular Genetic Laboratories
    • J.C. Latourelle, N. Pankratz, A. Dumitriu, J.B. Wilk, S. Goldwurm, G. Pezzoli, C.B. Mariani, A.L. DeStefano, C. Halter, J.F. Gusella PROGENI Investigators, Coordinators and Molecular Genetic Laboratories GenePD Investigators, Coordinators and Molecular Genetic Laboratories Genomewide association study for onset age in Parkinson disease BMC Med. Genet. 10 2009 98
    • (2009) BMC Med. Genet. , vol.10 , pp. 98
    • Latourelle, J.C.1    Pankratz, N.2    Dumitriu, A.3    Wilk, J.B.4    Goldwurm, S.5    Pezzoli, G.6    Mariani, C.B.7    Destefano, A.L.8    Halter, C.9    Gusella, J.F.10
  • 69
    • 79953124177 scopus 로고    scopus 로고
    • The effects of EBV transformation on gene expression levels and methylation profiles
    • M. Çalşkan, D.A. Cusanovich, C. Ober, and Y. Gilad The effects of EBV transformation on gene expression levels and methylation profiles Hum. Mol. Genet. 20 2011 1643 1652
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 1643-1652
    • Çalşkan, M.1    Cusanovich, D.A.2    Ober, C.3    Gilad, Y.4


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