Squalene mono-oxygenase, a key enzyme in cholesterol synthesis, is stabilized by unsaturated fatty acids

Biochemical Journal

Volumn 461, Issue 3, 2014, Pages 435-442

  Stevenson, Julian ^a   Luu, Winnie ^a   Kristiana, Ika ^a   Brown, Andrew J ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Cholesterol; Lipid homoeostasis; MARCH6; Squalene mono oxygenase; Ubiquitination; Unsaturated fatty acids

Indexed keywords

OLEIC ACID; PALMITIC ACID; PHOSPHATIDYLCHOLINE; PROTEIN SM; SQUALENE; SQUALENE MONOOXYGENASE; STEARIC ACID; TRIACYLGLYCEROL; UBIQUITIN PROTEIN LIGASE E3;

ANIMAL CELL; ARTICLE; CHO CELL LINE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DRUG MECHANISM; HEK293 CELL LINE; LIPOGENESIS; NONHUMAN; PRIORITY JOURNAL; TURNOVER TIME; UBIQUITINATION;

ACYL COENZYME A; ANIMALS; CHO CELLS; CRICETULUS; ENZYME STABILITY; FATTY ACIDS, NONESTERIFIED; FATTY ACIDS, UNSATURATED; GENE SILENCING; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; KINETICS; MEMBRANE PROTEINS; OLEIC ACID; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SQUALENE MONOOXYGENASE; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84904095534     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20131404     Document Type: Article

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