Haploinsufficiency of an RB-E2F1-Condensin II Complex Leads to Aberrant Replication and Aneuploidy

Cancer Discovery

Volumn 4, Issue 7, 2014, Pages 840-853

  Coschi, Courtney H ^a   Ishak, Charles A ^a   Gallo, David ^b,c   Marshall, Aren ^a   Talluri, Srikanth ^a   Wang, Jianxin ^d   Cecchini, Matthew J ^a   Martens, Alison L ^a   Percy, Vanessa ^a   Welch, Ian ^a   Boutros, Paul C ^b,d   Brown, Grant W ^b,c   Dick, Frederick A ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b Western University ^*  (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CONDENSIN; RETINOBLASTOMA PROTEIN; SATELLITE DNA; TRANSCRIPTION FACTOR E2F1; ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; MULTIPROTEIN COMPLEX;

AMINO ACID SUBSTITUTION; ANEUPLOIDY; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER INCIDENCE; CARCINOGENESIS; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME ABERRATION; CHROMOSOME SEGREGATION; CHROMOSOME STRUCTURE; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA DAMAGE; DNA REPLICATION; GENE; GENE DOSAGE; GENOMIC INSTABILITY; HAPLOINSUFFICIENCY; HUMAN; HUMAN CELL; MITOSIS; MOUSE; NONHUMAN; PERICENTROMERE; PHENOTYPE; PHOSPHORYLATION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CENTROMERE; FIBROBLAST; GENETICS; METABOLISM; NEOPLASM; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATASES; ANEUPLOIDY; ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; CENTROMERE; DNA COPY NUMBER VARIATIONS; DNA REPLICATION; DNA-BINDING PROTEINS; E2F1 TRANSCRIPTION FACTOR; EMBRYO, MAMMALIAN; FIBROBLASTS; HAPLOINSUFFICIENCY; HUMANS; MICE; MULTIPROTEIN COMPLEXES; NEOPLASMS; RETINOBLASTOMA PROTEIN;

EID: 84904044770     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-14-0215     Document Type: Article

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