Rb1 haploinsufficiency promotes telomere attrition and radiation-induced genomic instability

Cancer Research

Volumn 73, Issue 14, 2013, Pages 4247-4255

  Gonzalez Vasconcellos, Iria ^a   Anastasov, Natasa ^a   Sanli Bonazzi, Bahar ^a   Klymenko, Olena ^a   Atkinson, Michael J ^a,b   Rosemann, Michael ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOBLASTOMA PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL CYCLE ARREST; CELL LINEAGE; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; GENE FUNCTION; GENE IDENTIFICATION; GENETIC SUSCEPTIBILITY; GENOMIC INSTABILITY; GERMLINE MICRONUCLEUS; HAPLOINSUFFICIENCY; MOUSE; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; RADIATION EXPOSURE; RADIATION INDUCED NEOPLASM; RB1 GENE; TELOMERE; TELOMERE ATTRITION; TELOMERE HOMEOSTASIS;

ANIMALS; BONE NEOPLASMS; CELL CYCLE CHECKPOINTS; CELLS, CULTURED; GENES, RETINOBLASTOMA; GENETIC PREDISPOSITION TO DISEASE; GENOMIC INSTABILITY; HAPLOINSUFFICIENCY; MICE; OSTEOSARCOMA; RADIATION; RETINOBLASTOMA PROTEIN; TELOMERE;

EID: 84880914664     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3117     Document Type: Article

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