-
1
-
-
0034752311
-
Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease
-
Allison AC, Cacabelos R, Lombardi VR, Alvarez XA, Vigo C. 2001. Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease. Prog Neuropsychopharmacol 25: 1341-1357.
-
(2001)
Prog Neuropsychopharmacol
, vol.25
, pp. 1341-1357
-
-
Allison, A.C.1
Cacabelos, R.2
Lombardi, V.R.3
Alvarez, X.A.4
Vigo, C.5
-
2
-
-
20344387475
-
Autophagy: Dual roles in life and death?
-
Baehrecke EH. 2005. Autophagy: Dual roles in life and death? Nat Rev Mol Cell Biol 6: 505-510.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 505-510
-
-
Baehrecke, E.H.1
-
3
-
-
33847278423
-
Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)
-
Brinker AM, Ma J, Lipsky PE, Raskin I. 2007. Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae). Phytochemistry 68: 732-766.
-
(2007)
Phytochemistry
, vol.68
, pp. 732-766
-
-
Brinker, A.M.1
Ma, J.2
Lipsky, P.E.3
Raskin, I.4
-
4
-
-
33747102122
-
A systematic review of randomised clinical trials of Tripterygium wilfordii for rheumatoid arthritis
-
Canter PH, Lee HS, Ernst E. 2006. A systematic review of randomised clinical trials of Tripterygium wilfordii for rheumatoid arthritis. Phytomedicine 13: 371-377.
-
(2006)
Phytomedicine
, vol.13
, pp. 371-377
-
-
Canter, P.H.1
Lee, H.S.2
Ernst, E.3
-
5
-
-
38349043984
-
Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species
-
Chen YQ, McMillan-Ward E, Kong JM, Israels SJ, Gibson SB. 2007. Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci 120: 4155-4166.
-
(2007)
J Cell Sci
, vol.120
, pp. 4155-4166
-
-
Chen, Y.Q.1
McMillan-Ward, E.2
Kong, J.M.3
Israels, S.J.4
Gibson, S.B.5
-
6
-
-
50649125120
-
Taxol induces caspase-independent cytoplasmic vacuolization and cell death through endoplasmic reticulum (ER) swelling in ASTC-a-1cells
-
Chen TS, Wang XP, Sun L, Wang LX, Xing D, Mok M. 2008a. Taxol induces caspase-independent cytoplasmic vacuolization and cell death through endoplasmic reticulum (ER) swelling in ASTC-a-1cells. Cancer Lett 18: 164-172.
-
(2008)
Cancer Lett
, vol.18
, pp. 164-172
-
-
Chen, T.S.1
Wang, X.P.2
Sun, L.3
Wang, L.X.4
Xing, D.5
Mok, M.6
-
7
-
-
37349067228
-
Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
-
Chen YQ, McMillan-Ward E, Kong JM, Israels SJ, Gibson SB. 2008b. Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death Differ 15: 171-182.
-
(2008)
Cell Death Differ
, vol.15
, pp. 171-182
-
-
Chen, Y.Q.1
McMillan-Ward, E.2
Kong, J.M.3
Israels, S.J.4
Gibson, S.B.5
-
8
-
-
35948986297
-
Absence of Bax switched MG132-induced apoptosis to non-apoptotic cell death that could be suppressed by transcriptional or translational inhibition
-
Ding WX, Ni HM, Yin XM. 2007. Absence of Bax switched MG132-induced apoptosis to non-apoptotic cell death that could be suppressed by transcriptional or translational inhibition. Apoptosis 12: 2233-2244.
-
(2007)
Apoptosis
, vol.12
, pp. 2233-2244
-
-
Ding, W.X.1
Ni, H.M.2
Yin, X.M.3
-
9
-
-
79955674412
-
Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans
-
Erdélyi P, Borsos E, Takács-Vellai K, Kovács T, Kovács AL, Sigmond T, Hargitai B, Pásztor L, Sengupta T, Dengg M, Pécsi I, Tóth J, Nilsen H, Vértessy BG, Vellai T. 2011. Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans. J Cell Sci 124: 1510-1518.
-
(2011)
J Cell Sci
, vol.124
, pp. 1510-1518
-
-
Erdélyi, P.1
Borsos, E.2
Takács-Vellai, K.3
Kovács, T.4
Kovács, A.L.5
Sigmond, T.6
Hargitai, B.7
Pásztor, L.8
Sengupta, T.9
Dengg, M.10
Pécsi, I.11
Tóth, J.12
Nilsen, H.13
Vértessy, B.G.14
Vellai, T.15
-
10
-
-
43949123587
-
Fenretinide induces autophagic cell death in caspase-defective breast cancer cells
-
Fazi B, Bursch W, Fimia GM, Nardacci R, Piacentini M, Di Sano F, Piredda L. 2008. Fenretinide induces autophagic cell death in caspase-defective breast cancer cells. Autophagy 4: 435-441.
-
(2008)
Autophagy
, vol.4
, pp. 435-441
-
-
Fazi, B.1
Bursch, W.2
Fimia, G.M.3
Nardacci, R.4
Piacentini, M.5
Di Sano, F.6
Piredda, L.7
-
11
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D, Kimchi A. 2004. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23: 2891-2906.
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
12
-
-
77956324704
-
Taxol induces concentration-dependent apoptotic and paraptosis-like cell death in human lung adenocarcinoma (ASTC-a-1) cells
-
Guo WJ, Chen TS, Wang XP, Chen R. 2010. Taxol induces concentration-dependent apoptotic and paraptosis-like cell death in human lung adenocarcinoma (ASTC-a-1) cells. J X-ray Sci Technol 18: 293-308.
-
(2010)
J X-ray Sci Technol
, vol.18
, pp. 293-308
-
-
Guo, W.J.1
Chen, T.S.2
Wang, X.P.3
Chen, R.4
-
13
-
-
67651100666
-
A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells
-
Karl R, Singha PK, Venkatachalam MA, Saikumar P. 2009. A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells. Oncogene 28: 2556-2568.
-
(2009)
Oncogene
, vol.28
, pp. 2556-2568
-
-
Karl, R.1
Singha, P.K.2
Venkatachalam, M.A.3
Saikumar, P.4
-
14
-
-
57649149333
-
Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009
-
Kroemer GL, Galluzzi P, Vandenabeele P, Abram J, Alnemri ES, Baehrecke EH, Blagosklonny MV, El-Deiry WS, Golstein P, Green DR, Hengartner M, Knight RA, Kumar S, Lipton SA, Malorni W, Nunez G, Peter ME, Tschopp J, Yuan J, Piacentini M, Zhivotovsky B, Melino G. 2009. Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 16: 3-11.
-
(2009)
Cell Death Differ
, vol.16
, pp. 3-11
-
-
Kroemer, G.L.1
Galluzzi, P.2
Vandenabeele, P.3
Abram, J.4
Alnemri, E.S.5
Baehrecke, E.H.6
Blagosklonny, M.V.7
El-Deiry, W.S.8
Golstein, P.9
Green, D.R.10
Hengartner, M.11
Knight, R.A.12
Kumar, S.13
Lipton, S.A.14
Malorni, W.15
Nunez, G.16
Peter, M.E.17
Tschopp, J.18
Yuan, J.19
Piacentini, M.20
Zhivotovsky, B.21
Melino, G.22
more..
-
15
-
-
33750008443
-
Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinine methide triterpenoid
-
Lee JH, Koo TH, Yoon H, Jung HS, Jin HZ, Lee K, Hong YS, Lee JJ. 2006. Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinine methide triterpenoid. Biochem Pharmacol 72: 1311-1321.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1311-1321
-
-
Lee, J.H.1
Koo, T.H.2
Yoon, H.3
Jung, H.S.4
Jin, H.Z.5
Lee, K.6
Hong, Y.S.7
Lee, J.J.8
-
16
-
-
66249085237
-
The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib
-
Milani M, Rzymski T, Mellor HR, Pike L, Bottini A, Generali D, Harris AL. 2009. The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib. Cancer Res 69: 4415-4423.
-
(2009)
Cancer Res
, vol.69
, pp. 4415-4423
-
-
Milani, M.1
Rzymski, T.2
Mellor, H.R.3
Pike, L.4
Bottini, A.5
Generali, D.6
Harris, A.L.7
-
17
-
-
33749352630
-
Endoplasmic reticulum vacuolization and valosin-containing protein relocalization result from simultaneous hsp90 inhibition by geldanamycin and proteasome inhibition by velcade
-
Mimnaugh EG, Xu W, Vos M, Yuan X, Neckers L. 2006. Endoplasmic reticulum vacuolization and valosin-containing protein relocalization result from simultaneous hsp90 inhibition by geldanamycin and proteasome inhibition by velcade. Mol Cancer Res 4: 667-681.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 667-681
-
-
Mimnaugh, E.G.1
Xu, W.2
Vos, M.3
Yuan, X.4
Neckers, L.5
-
18
-
-
2842616065
-
Apoptosis induction in HL-60cells and inhibition of topoisomerase II by triterpene celastrol
-
Nagase M, Oto J, Sugiyama S, Yube K, Takaishi Y, Sakato N. 2003. Apoptosis induction in HL-60cells and inhibition of topoisomerase II by triterpene celastrol. Biosci Biotechnol Biochem 67: 1883-1887.
-
(2003)
Biosci Biotechnol Biochem
, vol.67
, pp. 1883-1887
-
-
Nagase, M.1
Oto, J.2
Sugiyama, S.3
Yube, K.4
Takaishi, Y.5
Sakato, N.6
-
19
-
-
79955676537
-
Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics
-
O'Donovan TR, O'Sullivan GC, McKenna S. 2011. Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 7: 509-524.
-
(2011)
Autophagy
, vol.7
, pp. 509-524
-
-
O'Donovan, T.R.1
O'Sullivan, G.C.2
McKenna, S.3
-
21
-
-
0034687754
-
An alternative, nonapoptotic form of programmed cell death
-
Sperandio S, de Belle I, Bredesen DE. 2000. An alternative, nonapoptotic form of programmed cell death. Proc Natl Acad Sci 97: 14376-14381.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 14376-14381
-
-
Sperandio, S.1
de Belle, I.2
Bredesen, D.E.3
-
22
-
-
5044249067
-
Paraptosis: Mediation by MAP kinases and inhibition by AIP-1/Alix
-
Sperandio S, Poksay K, de Belle I, Lafuente MJ, Liu B, Nasir J, Bredesen DE. 2004. Paraptosis: Mediation by MAP kinases and inhibition by AIP-1/Alix. Cell Death Differ 11: 1066-1075.
-
(2004)
Cell Death Differ
, vol.11
, pp. 1066-1075
-
-
Sperandio, S.1
Poksay, K.2
de Belle, I.3
Lafuente, M.J.4
Liu, B.5
Nasir, J.6
Bredesen, D.E.7
-
23
-
-
78649793951
-
Identification of new modulators and protein alterations in non-apoptotic programmed cell death
-
Sperandio S, Poksay KS, Schilling B, Crippen D, Gibson BW, Bredesen DE. 2010. Identification of new modulators and protein alterations in non-apoptotic programmed cell death. J Cell Biochem 111: 1401-1412.
-
(2010)
J Cell Biochem
, vol.111
, pp. 1401-1412
-
-
Sperandio, S.1
Poksay, K.S.2
Schilling, B.3
Crippen, D.4
Gibson, B.W.5
Bredesen, D.E.6
-
24
-
-
70349921403
-
Molecular mechanism of inhibition of the human protein complex Hsp90-Cdc37, a kinome chaperone-cochaperone, by triterpene celastrol
-
Sreeramulu S, Gande SL, Gobel M, Schwalbe H. 2009. Molecular mechanism of inhibition of the human protein complex Hsp90-Cdc37, a kinome chaperone-cochaperone, by triterpene celastrol. Angew Chem Int Ed 48: 5853-5855.
-
(2009)
Angew Chem Int Ed
, vol.48
, pp. 5853-5855
-
-
Sreeramulu, S.1
Gande, S.L.2
Gobel, M.3
Schwalbe, H.4
-
25
-
-
69949155034
-
The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells
-
Tardito S, Isella C, Medico E, Marchio L, Bevilacqua E, Hatzoglou M, Bussolati O, Franchi-Gazzola R. 2009. The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells. J Boil Chem 284: 24306-24319.
-
(2009)
J Boil Chem
, vol.284
, pp. 24306-24319
-
-
Tardito, S.1
Isella, C.2
Medico, E.3
Marchio, L.4
Bevilacqua, E.5
Hatzoglou, M.6
Bussolati, O.7
Franchi-Gazzola, R.8
-
26
-
-
48349087467
-
Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells
-
Wu WK, Wu YC, Yu L, Li ZJ, Sung JJ, Cho CH. 2008. Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells. Biochem Bioph Res Co 374: 258-263.
-
(2008)
Biochem Bioph Res Co
, vol.374
, pp. 258-263
-
-
Wu, W.K.1
Wu, Y.C.2
Yu, L.3
Li, Z.J.4
Sung, J.J.5
Cho, C.H.6
-
27
-
-
77951217000
-
Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase
-
Wu YT, Tan HL, Shui GH, Bauvy C, Huang Q, Wenk RM, Ong CN, Codogno P, Shen HM. 2010. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem 285: 10850-10861.
-
(2010)
J Biol Chem
, vol.285
, pp. 10850-10861
-
-
Wu, Y.T.1
Tan, H.L.2
Shui, G.H.3
Bauvy, C.4
Huang, Q.5
Wenk, R.M.6
Ong, C.N.7
Codogno, P.8
Shen, H.M.9
-
28
-
-
79952234227
-
Autophagy inhibition enhances etoposide-induced cell death in human hepatoma G2cells
-
Xie BS, Zhao HC, Yao SK, Zhuo DX, Jin B, Lv DC, Wu CL, Ma DL, Gao C, Shu XM, Ai ZL. 2011. Autophagy inhibition enhances etoposide-induced cell death in human hepatoma G2cells. Int J Mol Med 27: 599-606.
-
(2011)
Int J Mol Med
, vol.27
, pp. 599-606
-
-
Xie, B.S.1
Zhao, H.C.2
Yao, S.K.3
Zhuo, D.X.4
Jin, B.5
Lv, D.C.6
Wu, C.L.7
Ma, D.L.8
Gao, C.9
Shu, X.M.10
Ai, Z.L.11
-
29
-
-
33646406554
-
Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine" is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice
-
Yang H, Chen D, Cui QC, Yuan X, Dou QP. 2006. Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine" is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. Cancer Res 66: 4758-4765.
-
(2006)
Cancer Res
, vol.66
, pp. 4758-4765
-
-
Yang, H.1
Chen, D.2
Cui, Q.C.3
Yuan, X.4
Dou, Q.P.5
-
30
-
-
75149124278
-
Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells
-
Yoon MJ, Kim EH, Lim JH, Kwon TK, Choi KS. 2010. Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells. Free Radic Biol Med 48: 713-726.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 713-726
-
-
Yoon, M.J.1
Kim, E.H.2
Lim, J.H.3
Kwon, T.K.4
Choi, K.S.5
-
31
-
-
43849085358
-
Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network
-
Yue QX, Cao ZW, Guan SH, Liu XH, Tao L, Wu WY, Li YX, Yang PY, Liu X, Guo DA. 2008. Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network. Mol Cell Proteomics 7: 949-961.
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 949-961
-
-
Yue, Q.X.1
Cao, Z.W.2
Guan, S.H.3
Liu, X.H.4
Tao, L.5
Wu, W.Y.6
Li, Y.X.7
Yang, P.Y.8
Liu, X.9
Guo, D.A.10
-
32
-
-
75149175502
-
Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells
-
Zhu K, Dunner K, McConkey DJ. 2010. Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells. Oncogene 29: 451-462.
-
(2010)
Oncogene
, vol.29
, pp. 451-462
-
-
Zhu, K.1
Dunner, K.2
McConkey, D.J.3
|