Celastrol isolated from Tripterygium regelii induces apoptosis through both caspase-dependent and -independent pathways in human breast cancer cells

Food and Chemical Toxicology

Volumn 49, Issue 2, 2011, Pages 527-532

  Yang, Hee Sun ^a   Kim, Jae Yong ^a   Lee, Ju Hye ^a   Lee, Byong Won ^b   Park, Ki Hun ^b   Shim, Ki Hwan ^b   Lee, Mi Kyung ^a   Seo, Kwon Il ^a  

^a Sunchon National University   (South Korea)

^b Gyeongsang National University   (South Korea)

Author keywords

Apoptosis; Celastrol; MCF 7; Tripterygium regelii

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 7; CASPASE 8; CASPASE 9; CELASTROL; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID;

APOPTOSIS; ARTICLE; BARK; CANCER CELL; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG STRUCTURE; ENZYME ACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRION; PROTEIN EXPRESSION; TRIPTERYGIUM; TRIPTERYGIUM REGELII;

ACTINS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BREAST NEOPLASMS; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR STRUCTURE; TRIPTERYGIUM; TRITERPENES;

TRIPTERYGIUM REGELII;

EID: 78951492587     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.11.044     Document Type: Article

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