An investigation of in vitro cytotoxicity and apoptotic potential of aromatic diselenides

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 15, 2014, Pages 3440-3446

  Rizvi, Masood Ahmad ^a   Guru, Santosh ^b   Naqvi, Tahira ^a   Kumar, Manjeet ^b   Kumbhar, Navanath ^c   Akhoon, Showkat ^a   Banday, Shazia ^a   Singh, Shashank K ^b   Bhushan, Shashi ^b   Mustafa Peerzada, G ^a   Shah, Bhahwal Ali ^b  

^a UNIVERSITY OF KASHMIR   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^c UNIVERSITY OF PUNE   (India)

Author keywords

Anti cancer; Apoptosis; Diselenides; DNA binding; In silico

Indexed keywords

1,2 BIS(2 ETHYLPHENYL)DISELANE; 1,2 BIS(2 HYDROXYPHENYL)DISELANE; 1,2 BIS(2,6 DIMETHYLPHENYL)DISELANE; 1,2 BIS(3,5 DIMETHYLPHENYL)DISELANE; 1,2 BIS(4 HYDXOXYPHENYL)DISELANE; 1,2 BIS(4 METHOXYPHENYL)DISELANE; 1,2 BIS(4 METHYLPHENYL)DISELANE; 1,2 BIS(NAPHTHALEN 1 YL)DISELANE; 1,2 BIS[3,5 BIS(TRIFLUOROMETHYL)PHENYL]DISELANE; 1,2 DI(PYRIDINE 2 YL)DISELANE; 1,2 DIPHENYLSELANE; ANTINEOPLASTIC AGENT; AROMATIC DISELENIDE; UNCLASSIFIED DRUG; [DISELANEDIYLBIS(1,2 PHENYLENE)]DIMETHANOL; [DISELANEDIYLBIS(1,4 PHENYLENE)]DIMETHANOL; (DISELANEDIYLBIS(1,2 PHENYLENE))DIMETHANOL; AROMATIC COMPOUND; DNA; ORGANOSELENIUM DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER CELL LINE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CULTURE; CELL CYCLE; CELL CYCLE S PHASE; CELL GROWTH; CYTOTOXICITY; DNA BINDING; DRUG SYNTHESIS; GROWTH INHIBITION; HCT116 CELL LINE; HL 60 CELL LINE; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR DOCKING; NUCLEAR MICROSCOPY; PHASE CONTRAST MICROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; ANTINEOPLASTIC ACTIVITY; BINDING AFFINITY; CANCER INHIBITION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CHEMICAL PHENOMENA; DNA DAMAGE; HYDROPHOBICITY; IN VITRO STUDY; INTERACTIONS WITH DNA; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; MCF 7 CELL LINE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; MCF-7 CELLS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANOSELENIUM COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84904042653     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.05.075     Document Type: Article

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