Structure-activity relationship (SAR) of parthenin analogues with pro-apoptotic activity: Development of novel anti-cancer leads

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 15, 2009, Pages 4394-4398

  Shah, Bhahwal Ali ^a   Kaur, Rajbir ^a   Gupta, Pankaj ^a   Kumar, Ajay ^a   Sethi, Vijay Kumar ^a   Andotra, Samar Singh ^a   Singh, Jaswant ^a   Saxena, Ajit Kumar ^a   Taneja, Subhash Chandra ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Apoptosis; Cytotoxicity; Parthenin; SAR; Telomerase; Topoisomerase II

Indexed keywords

ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); PARTHENIN; PARTHENIN DERIVATIVE; TELOMERASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HELA CELLS; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; NEOPLASMS; PLASMIDS; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP; TELOMERASE; TOPOISOMERASE II INHIBITORS;

EID: 67649990522     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.05.089     Document Type: Article

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