A propionyloxy derivative of 11-keto-β-boswellic acid induces apoptosis in HL-60 cells mediated through topoisomerase i & II inhibition

Chemico-Biological Interactions

Volumn 189, Issue 1-2, 2011, Pages 60-71

  Chashoo, Gousia ^a   Singh, Shashank K ^a   Sharma, Paraduman R ^a   Mondhe, Dilip M ^a   Hamid, Abid ^a   Saxena, Arpita ^a   Andotra, Samar S ^a   Shah, Bhahwal A ^a   Qazi, Naveed A ^a   Taneja, Subhash C ^a   Saxena, Ajit K ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Boswellia serrata; Caspase; HL 60; Propionyloxy derivative of KBA; Topoisomerase

Indexed keywords

3 ALPHA PROPIONYLOXY 11 KETO BETA BOSWELLIC ACID; CASPASE; CYTOCHROME C; DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); FLUOROURACIL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SODIUM CHLORIDE; TERPENOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL STRAIN HL 60; CELL STRAIN MCF 7; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG SYNTHESIS; EHRLICH ASCITES TUMOR; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEUROBLASTOMA; NONHUMAN; OVARY CANCER; PROMYELOCYTIC LEUKEMIA; PROSTATE CANCER; PROTEIN CLEAVAGE; SARCOMA 180;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; COMET ASSAY; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; FLOW CYTOMETRY; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICROSCOPY, ELECTRON, SCANNING; PROPIONATES; RANDOM ALLOCATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TOPOISOMERASE INHIBITORS; TRITERPENES;

BOSWELLIA SERRATA; CITRUS MACROPHYLLA; MURINAE;

EID: 79251648545     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.10.017     Document Type: Article

References (30)

1. D. Hanahan, and R.A. Weinberg The hallmark of cancer Cell 100 2000 57 70
2. K.M. Debatin Activation of apoptosis pathways by anticancer treatment Toxicol. Lett. 112/113 2000 41 48
3. H. Zou, W.J. Liu, X. Henzel, A. Lutschg, and X. Wang Apaf-1, A human protein homologous to C. elegans CED-4 participates in cytochrome c-dependent activation of caspase-3 Cell 90 1997 405 413
4. N.R. Farnsworth, O. Akerele, A.S. Bingel, D.D. Soejarto, and Z. Guo The value of plants used in traditional medicines for drug discovery Environ. Health Prospect. 63 1985 965 981
5. D.J. Newman, G.M. Cragg, and K.M. Snader Natural products as source of new drugs over the period J. Nat. Prod. 66 2003 1022 1037
6. R. Han Highlight on the studies of anticancer drugs derived from plants in China Stem Cells 12 1994 53 63
7. H. Safayhi, T. Mack, J. Sabieraj, M.I. Anazodo, L.R. Subramanian, and H.P. Ammon Boswellic acids: novel, specific, non-redox inhibitors of 5-lipoxygenase J. Pharmacol. Exp. Ther. 26 1992 1143 1146
8. R.F. Hoernlein, T.H. Orlikowsky, and C. Zehrer Acetyl-11- keto-beta-boswellic acid induce apoptosis in HL-60 and CCRFCEM cells and inhibit topoisomerase-I J Pharmacol. Exp. Ther. 288 1999 613 619
9. B.A. Shah, G.N. Qazi, and S.C. Taneja Boswellic acids: a group of medicinally important compounds Nat. Prod. Rep. 26 2009 72 89
10. S. Kaur, S. Kamboj, J. Singh, A.K. Saxena, and V.A. Dhuna Isolation of a novel N-acetyl-d-lactosamine specific lectin from Alocasia cucullata (Schott.) Biotechnol. Lett. 27 2005 1815 1820
11. M.T. Muller, and R.W. Hoepner Topoisomerase I is the predominant nuclear protein from avian erythrocytes that can be covalently linked to DNA Biochem. J. 226 1985 873 878
12. O.S. Frankfurt, and A. Krishnan Apoptosis based drug screening and detection of selective toxicity to cancer cells Anti Cancer Drugs 14 2003 555 561
13. Shougang Zhuang, and Gabriel Simon Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells Am. J. Physiol. Cell. Physiol. 279 2000 341 351
14. S. Rello, J.C. Stockert, V. Moreno, A. Gámez, M. Pacheco, A. Juarranz, M. Canete, and A. Villanueva Morphological criteria to distinguish cell death induced by apoptotic and necrotic treatments Apoptosis 10 2005 201 208
15. P.R. Sharma, D.M. Mondhe, S. Muthiah, H.C. Pal, A.K. Shahi, A.K. Saxena, and G.N. Qazi Anticancer activity of an essential oil from Cymbopogon flexuosus Chem. Biol. Interact. 179 2009 160 168
16. I. Vernes, C. Haanen, H. Steffen-Nakken, and C. Reutellingsperger A novel assay for apoptosis, Flow cytometric detection of phosphotidylserine expression on early apoptotic cells using fluorescein labeled Annexin V J. Immunol. Methods 184 1995 39 51
17. S. Bhushan, A. Kumar, F. Malik, S.S. Andotra, V.K. Sethi, I.P. Kumar, S.K. Taneja, G.N. Qazi, and J. Singh A tritepenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells Apoptosis 12 2007 1911 1926
18. N.P. Singh, M.T. McCoy, R.R. Tice, and E.L. Schneider A simple technique for quantitation of low levels of DNA damage in individual cells Exp. Cell Res. 175 1988 184 191
19. D.J. Waxman, and P.S. Schwartz Harnessing apoptosis for improved anti-cancer gene therapy Cancer Res. 63 2003 8563 8572
20. S. Desagher, S. Osen, A. Nicholas, R. Eskes, S. Montessuit, S. Lauper, K. Maundrell, B. Antonsson, and J.C. Hartinsu Bid induced conformational change of Bax is responsible for mitochondrial cytochrome C release during apoptosis J. Cell Biol. 144 1999 891 901
21. S. Bhushan, J. Singh, M.J. Rao, A.K. Saxena, and G.N. Qazi A novel lignin composition from cedrus deodara induces apoptosis and early nitric oxide generation in human leukaemia Molt-4 and HL-60 cells Nitric oxide 14 2006 72 88
22. M. Yingchang, S.D. Thomas, X. Xiaohua, L.K. Casson, D.M. Miller, and P.J. Bates Apoptosis in leukemia cell is accompanied by alterations in the level and localization of nucleolin J. Biol. Chem. 278 2003 8572 8579
23. M.D. Seudiero, P. Skehan, R. Shoemaker, K. Paull, D. Vistica, C. Hose, J. Langley, P. Cronise, A. Vaigro-WolV, M. Gray-Goodrich, H. Campbell, J. Mayo, and M. Boyd Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumorcell lines J. Natl. Cancer Inst. 83 1991 757 766
24. M. Loss, M. Van de Craen, L.C. Penning, H. Schenk, M. Western drop, P.A. Baeuerele, W. Droge, P.H. Krammer, W. Fiers, and K. Schulze-Osthoff Requirement of an ICE/CED-3 protease for FAS/APO-1 mediated apoptosis Nature 375 1995 81 83
25. D.A. Burden, and N. Osheroff Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme Biochim. Biophys. Acta 1400 1998 139 154
26. Manon van Engeland, Luc J.W. Nieland, Frans C.S. Ramaekers, B. Schutte, and Chris P.M. Reutelingsperger Annexin V-affinity assay, a review on an apoptosis detection system based on phosphatidylserine exposure Cytometry 31 2008 1 9
27. L. Ahmad, S. Jalali, S.A. Shami, and Z. Akram Sperm preparation, DNA damage by comet assay in normo- and teratozoospermics Syst. Biol. Reprod. Med. 53 2007 325 338
28. M. Chen, and J. Wang Initiator caspases in apoptosis signalling pathways Apoptosis 7 2002 313 319
29. D.R. Green, and J.C. Reed Mitochondria and apoptosis Science 281 1998 1309 1312
30. J. Henry-Mowatt, C. Dive, J.C. Martinou, and D. James Role of mitochondrial membrane permeabilization in apoptosis and cancer Oncogene 23 2004 2850 2860