Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation

International Immunopharmacology

Volumn 22, Issue 1, 2014, Pages 151-159

  Ma, Bo ^a   Meng, Xiangbao ^a   Wang, Jing ^a   Sun, Jing ^a   Ren, Xiaoyu ^a,b   Qin, Meng ^a   Sun, Jie ^a   Sun, Guibo ^a   Sun, Xiaobo ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b EASTERN LIAONING UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid ; Apoptosis; MAPK; Notoginsenoside R1; PC12

Indexed keywords

AMYLOID BETA PROTEIN; FREE RADICAL; MITOGEN ACTIVATED PROTEIN KINASE; NOTOGINSENOSIDE R1; PANAX NOTOGINSENG EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; GINSENOSIDE; NEUROPROTECTIVE AGENT;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL VIABILITY; DEGENERATIVE DISEASE; ENZYME ACTIVATION; INCUBATION TIME; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PANAX NOTOGINSENG; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; HUMAN; METABOLISM; NECROSIS; NERVE CELL; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; GINSENOSIDES; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOGEN-ACTIVATED PROTEIN KINASES; NECROSIS; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PANAX NOTOGINSENG; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84903997103     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.06.018     Document Type: Article

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