Olfactory ensheathing cells conditioned medium prevented apoptosis induced by 6-OHDA in PC12 cells through modulation of intrinsic apoptotic pathways

International Journal of Developmental Neuroscience

Volumn 26, Issue 3-4, 2008, Pages 323-329

  Feng, Lei ^a   Meng, Haiwei ^a   Wu, Fengxia ^a   Cheng, Baohua ^a   He, Xiuquan ^a   Wang, Xiaohong ^a   Li, Zhengping ^a   Liu, Shuwei ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

6 OHDA; Apoptosis; Bax; Bcl 2; Mitochondrial membrane potential; Olfactory ensheathing cells; PC12 cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; HOE 33342; OXIDOPAMINE; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NEWBORN; NONHUMAN; OLFACTORY ENSHEATHING CELL; PRIORITY JOURNAL; RAT; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZIMIDAZOLES; BIOLOGICAL ASSAY; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; INDICATORS AND REAGENTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NERVE DEGENERATION; NERVE GROWTH FACTORS; NEUROGLIA; NEURONS; NEUROTOXINS; OLFACTORY BULB; OXIDOPAMINE; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; TETRAZOLIUM SALTS; THIAZOLES;

RATTUS;

EID: 41649092431     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2008.01.003     Document Type: Article

References (39)

1. Agrawal A.K., Shukla S., Chaturvedi R.K., Seth K., Srivastava N., Ahmad A., and Seth P.K. Olfactory ensheathing cell transplantation restores functional deficits in rat model of Parkinson's disease: a cotransplantation approach with fetal ventral mesencephalic cells. Neurobiol. Dis. 16 (2004) 516-526
2. Barnett S.C. Olfactory ensheathing cells: unique glial cell types?. J. Neurotrauma 21 (2004) 375-382
3. Barnett S.C., Alexander C.L., Iwashita Y., Gilson J.M., Crowther J., Clark L., Dunn L.T., Papanastassiou V., Kennedy P.G., and Franklin R.J. Identification of a human olfactory ensheathing cell that can effect transplant-mediated remyelination of demyelinated CNS axons. Brain 123 8 (2000) 1581-1588
4. Blum D., Torch S., Nissou M.F., Benabid A.L., and Verna J.M. Extracellular toxicity of 6-hydroxydopamine on PC12 cells. Neurosci. Lett. 283 3 (2000) 193-196
5. Chung R.S., Woodhouse A., Fung S., Dickson T.C., West A.K., Vickers J.C., and Chuah M.I. Olfactory ensheathing cells promote neurite sprouting of injured axons in vitro by direct cellular contact and secretion of soluble factors. Cell Mol. Life Sci. 61 10 (2004) 1238-1245
6. Cory S., and Adams J.M. The Bcl-2 family: regulators of cellular life-or-death switch. Nat. Rev. Cancer 2 9 (2002) 647-656
7. Deumens R., Koopmans G.C., Honig W.M., Hamers F.P., Maquet V., Jérôme R., Steinbusch H.W., and Joosten E.A. Olfactory ensheathing cells, olfactory nerve fibroblasts and biomatrices to promote long-distance axon regrowth and functional recovery in the dorsally hemisected adult rat spinal cord. Exp. Neurol. 200 1 (2006) 89-103
8. Fiskum G., Starkov A., Polster B.M., and Chinopoulos C. Mitochondrial mechanisms of neural cell death and neuroprotective interventions in Parkinson's disease. Ann. N. Y. Acad. Sci. 991 (2003) 111-119
9. Glinka Y., Gassen M., and Youdim M.B. Mechanism of 6-hydroxydopamine neurotoxicity. J. Neural. Transm. Suppl. 50 (1997) 55-66
10. Hammond C., Bergman H., and Brown P. Pathological synchronization in Parkinson's disease: networks, models and treatments. Trends Neurosci. 30 7 (2007) 357-364
11. Hartmann A., Michel P.P., Troadec J.D., Mouatt-Prigent A., Faucheux B.A., Ruberg M., Agid Y., and Hirsch E.C. Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?. J. Neurochem. 76 (2001) 1785-1793
12. Hashimoto Y., Shimada Y., Itami A., Ito T., Kawamura J., Kawabe A., Kaganoi J., Maeda M., Watanabe G., and Imamura M. Growth inhibition through activation of peroxisome proliferator-activated receptor gamma in human oesophageal squamous cell carcinoma. Eur. J. Cancer 39 15 (2003) 2239-2246
13. Herr I., and Debatin K.M. Cellular stress response and apoptosis in cancer therapy. Blood 98 (2001) 2603-2614
14. Johansson S., Lee I.H., Olson L., and Spenger C. Olfactory ensheathing glial co-grafts improve functional recovery in rats with 6-OHDA lesions. Brain 128 12 (2005) 2961-2976
15. Leaver S.G., Harvey A.R., and Plant G.W. Adult olfactory ensheathing glia promote the long-distance growth of adult retinal ganglion cell neurites in vitro. Glia 53 5 (2006) 467-476
16. Lee C.S., Song E.H., Park S.Y., and Han E.S. Combined effect of dopamine and MPP + on membrane permeability in mitochondria and cell viability in PC12 cells. Neurochem. Int. 43 2 (2003) 147-154
17. Lev N., Melamed E., and Offen D. Apoptosis and Parkinson's disease. Prog. Neuropsychopharmacol. Biol. Psychiatry 27 (2003) 245-250
18. Li Y., Field P.M., and Raisman G. Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells. Science 277 5334 (1997) 2000-2002
19. Li Y., Field P.M., and Raisman G. Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells. J. Neurosci. 18 24 (1998) 10514-10524
20. Li Y., Sauve Y., Li D., Lund R.D., and Raisman G. Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons. J. Neurosci. 23 (2003) 7783-7788
21. Lima C., Pratas-Vital J., Escada P., Hasse-Ferreira A., Capucho C., and Peduzzi J.D. Olfactory mucosa autografts in human spinal cord injury: a pilot clinical study. J. Spinal Cord Med. 29 (2006) 191-206
22. Lipson A.C., Widenfalk J., Lindqvist E., Ebendal T., and Olson L. Neurotrophic properties of olfactory ensheathing glia. Exp. Neurol. 180 (2003) 167-171
23. Lopez-Vales R., Fores J., Navarro X., and Verdu E. Chronic transplantation of olfactory ensheathing cells promotes partial recovery after complete spinal cord transection in the rat. Glia 55 (2007) 303-311
24. Lu J., Feron F., Mackay-Sim A., and Waite P.M. Olfactory ensheathing cells promote locomotor recovery after delayed transplantation into transected spinal cord. Brain 125 (2002) 14-21
25. Meng H., Li C., Feng L., Cheng B., Wu F., Wang X., Li Z., and Liu S. Effects of Ginkgolide B on 6-OHDA-induced apoptosis and calcium over load in cultured PC12. Int. J. Dev. Neurosci. 25 (2007) 509-514
26. Mitrovic B., Ignarro L.J., Vinters H.V., Akers M.A., Schmid I., Uittenbogaart C., and Merrill J.E. Nitric oxide induces necrotic but not apoptotic cell death in oligodendrocytes. Neuroscience 65 20 (1995) 531-539
27. Pascual J.I., Gudino-Cabrera G., Insausti R., and Nieto-Sampedro M. Spinal implants of olfactory ensheathing cells promote axon regeneration and bladder activity after bilateral lumbosacral dorsal rhizotomy in the adult rat. J. Urol. 167 (2002) 1522-1526
28. Pellitteri R., Spatuzza M., Russo A., and Stanzani S. Olfactory ensheathing cells exert a trophic effect on the hypothalamic neurons in vitro. Neurosci. Lett. 417 (2007) 24-29
29. Plant G.W., Christensen C.L., Oudega M., and Bunge M.B. Delayed transplantation of olfactory ensheathing glia promotes sparing/regeneration of supraspinal axons in the contused adult rat spinal cord. J. Neurotrauma 20 1 (2003) 1-16
30. Ramon-Cueto A., and Avila J. Olfactory ensheathing cells: properties and function. Brain Res. Bull. 46 (1998) 175-187
31. Ramón-Cueto A., and Nieto-Sampedro M. Regeneration into the spinal cord of transected dorsal root axons is promoted by ensheathing glia transplants. Exp. Neurol. 127 2 (1994) 232-244
32. Reed J.C. Apoptosis-regulating proteins as targets for drug discovery. Trends Mol. Med. 7 7 (2001) 314-319
33. Ruitenberg M.J., Levison D.B., Lee S.V., Verhaagen J., Harvey A.R., and Plant G.W. NT-3 expression from engineered olfactory ensheathing glia promotes spinal sparing and regeneration. Brain 128 (2005) 839-853
34. Sasaki M., Hains B.C., Lankford K.L., Waxman S.G., and Kocsis J.D. Protection of corticospinal tract neurons after dorsal spinal cord transection and engraftment of olfactory ensheathing cells. Glia 53 4 (2006) 352-359
35. 2 neurotoxicity. Neurosci. Lett. 305 (2001) 61-64
36. Wang Y.Z., Meng J.H., Yang H., Luo N., Jiao X.Y., and Ju G. Differentiation-inducing and protective effects of adult rat olfactory ensheathing cell conditioned medium on PC12 cells. Neurosci. Lett. 346 (2003) 9-12
37. Wei H., Kang B., Wei W., Liang G., Meng Q.C., Li Y., and Eckenhoff R.G. Isoflurane and sevoflurane affect cell survival and BCL-2/BAX ratio differently. Brain Res. 1037 (2005) 139-147
38. Woodhall E., West A.K., and Chuah M.I. Cultured olfactory ensheathing cells express nerve growth factor, brain-derived neurotrophic factor, glia cell line-derived neurotrophic factor and their receptors. Brain Res. Mol. Brain Res. 88 1-2 (2001) 203-213
39. Yamaguchi H., Bhalla K., and Wang H.G. Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria. Cancer Res. 63 7 (2003) 1483-1489