Multifunctional Disulfide-based cationic dextran conjugates for intravenous gene delivery targeting ovarian cancer cells

Molecular Pharmaceutics

Volumn 11, Issue 7, 2014, Pages 2250-2261

  Song, Yanyan ^a,b   Lou, Bo ^a,b   Zhao, Peng ^a   Lin, Chao ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b TONGJI UNIVERSITY   (China)

Author keywords

dextran; disulfide; ovarian cancer cells; systemic gene delivery; targeting

Indexed keywords

1,4 BIS(3 AMINOPROPYL)PIPERAZINE; 2 CARBOXYETHYL 2 PYRIDYL DISULFIDE; AMINE; ANTINEOPLASTIC AGENT; BETA GALACTOSIDASE; BIS(P NITROPHENYL) 3,3' DITHIODIPROPANOATE; DEXTRAN DERIVATIVE; DIMETHYL SULFOXIDE; DISULFIDE; FOLIC ACID; LIPOFECTAMINE; P NITROPHENYL CHLOROFORMATE; PIPERAZINE DERIVATIVE; PLASMID DNA; POLYAMIDE; POLYETHYLENEIMINE; UNCLASSIFIED DRUG; 1,4-BIS(3-AMINOPROPYL)PIPERAZINE; CATION; DEXTRAN; DNA; LIPID; NYLON; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; CANCER CELL; CONCENTRATION (PARAMETERS); CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA BINDING; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IC 50; IN VITRO GENE TRANSFER; IN VITRO STUDY; IN VIVO STUDY; MALE; MCF 7 CELL LINE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OVARY CANCER; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; TUMOR XENOGRAFT; ZETA POTENTIAL; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; NUDE MOUSE; OVARIAN NEOPLASMS; PROCEDURES; TUMOR CELL LINE;

ANIMALS; CATIONS; CELL LINE, TUMOR; DEXTRANS; DISULFIDES; DNA; FEMALE; FOLIC ACID; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; LIPIDS; MALE; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; NYLONS; OVARIAN NEOPLASMS; PIPERAZINES; POLYETHYLENEIMINE; POLYMERS; TRANSFECTION;

EID: 84903991609     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp4006672     Document Type: Article

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