-
2
-
-
1842477303
-
A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length
-
Langbehn, D.R., Brinkman, R.R., Falush, D., Paulsen, J.S. and Hayden, M.R. (2004) A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clin. Genet., 65, 267-277.
-
(2004)
Clin. Genet.
, vol.65
, pp. 267-277
-
-
Langbehn, D.R.1
Brinkman, R.R.2
Falush, D.3
Paulsen, J.S.4
Hayden, M.R.5
-
3
-
-
0019026208
-
Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
-
Embi, N., Rylatt, D.B. and Cohen, P. (1980) Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur. J. Biochem., 107, 519-527.
-
(1980)
Eur. J. Biochem.
, vol.107
, pp. 519-527
-
-
Embi, N.1
Rylatt, D.B.2
Cohen, P.3
-
4
-
-
77958597709
-
Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain
-
Soutar, M.P., Kim, W.Y., Williamson, R., Peggie, M., Hastie, C.J., McLauchlan, H., Snider, W.D., Gordon-Weeks, P.R. and Sutherland, C. (2010) Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain. J. Neurochem., 115, 974-983.
-
(2010)
J. Neurochem.
, vol.115
, pp. 974-983
-
-
Soutar, M.P.1
Kim, W.Y.2
Williamson, R.3
Peggie, M.4
Hastie, C.J.5
McLauchlan, H.6
Snider, W.D.7
Gordon-Weeks, P.R.8
Sutherland, C.9
-
5
-
-
0035413614
-
Glycogen synthase kinase-3: properties, functions, and regulation
-
Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem. Rev., 101, 2527-2540.
-
(2001)
Chem. Rev.
, vol.101
, pp. 2527-2540
-
-
Ali, A.1
Hoeflich, K.P.2
Woodgett, J.R.3
-
6
-
-
79959222357
-
Deconstructing GSK-3: The fine regulation of its activity
-
Medina, M. and Wandosell, F. (2011) Deconstructing GSK-3: The fine regulation of its activity. Int. J. Alzheimers Dis., 2011, 479249.
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 479249
-
-
Medina, M.1
Wandosell, F.2
-
7
-
-
79959233776
-
What are the bona fide GSK3 substrates?
-
Sutherland, C. (2011) What are the bona fide GSK3 substrates? Int. J. Alzheimers Dis., 2011, 505607.
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 505607
-
-
Sutherland, C.1
-
8
-
-
79955385225
-
The role of GSK3 in presynaptic function
-
Smillie, K.J. and Cousin, M.A. (2011) The role of GSK3 in presynaptic function. Int. J. Alzheimers Dis., 2011, 263673.
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 263673
-
-
Smillie, K.J.1
Cousin, M.A.2
-
9
-
-
78751644241
-
Dysregulation of glycogen synthase kinase-3 in skeletal muscle and the etiology of insulin resistance and type 2 diabetes
-
Henriksen, E.J. (2010) Dysregulation of glycogen synthase kinase-3 in skeletal muscle and the etiology of insulin resistance and type 2 diabetes. Curr. Diabetes Rev., 6, 285-293.
-
(2010)
Curr. Diabetes Rev.
, vol.6
, pp. 285-293
-
-
Henriksen, E.J.1
-
10
-
-
57349143530
-
Glycogen synthase kinase 3β (GSK3b) in tumorigenesis and cancer chemotherapy
-
Luo, J. (2009) Glycogen synthase kinase 3β (GSK3b) in tumorigenesis and cancer chemotherapy. Cancer Lett., 273, 194-200.
-
(2009)
Cancer Lett.
, vol.273
, pp. 194-200
-
-
Luo, J.1
-
11
-
-
0026487365
-
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase
-
Hanger, D.P., Hughes, K., Woodgett, J.R., Brion, J.P. and Anderton, B.H. (1992) Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci. Lett., 147, 58-62.
-
(1992)
Neurosci. Lett.
, vol.147
, pp. 58-62
-
-
Hanger, D.P.1
Hughes, K.2
Woodgett, J.R.3
Brion, J.P.4
Anderton, B.H.5
-
12
-
-
79959261693
-
Regulation of cell survival mechanisms in Alzheimer's disease by glycogen synthase kinase-3
-
Mines, M.A., Beurel, E. and Jope, R.S. (2011) Regulation of cell survival mechanisms in Alzheimer's disease by glycogen synthase kinase-3. Int. J. Alzheimers Dis., 2011, 861072.
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 861072
-
-
Mines, M.A.1
Beurel, E.2
Jope, R.S.3
-
13
-
-
84255190041
-
A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health
-
Beaulieu, J.M. (2012) A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health. J. Psychiatry Neurosci., 37, 7-16.
-
(2012)
J. Psychiatry Neurosci.
, vol.37
, pp. 7-16
-
-
Beaulieu, J.M.1
-
14
-
-
84870698291
-
Energy dysfunction in Huntington's disease: insights from PGC-1alpha, AMPK, andCKB.Cell Mol
-
Ju, T.C., Lin, Y.S. and Chern, Y. (2012) Energy dysfunction in Huntington's disease: insights from PGC-1alpha, AMPK, andCKB.Cell Mol. Life Sci., 69, 4107-4120.
-
(2012)
Life Sci.
, vol.69
, pp. 4107-4120
-
-
Ju, T.C.1
Lin, Y.S.2
Chern, Y.3
-
15
-
-
0346749473
-
Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells
-
Gines, S., Ivanova, E., Seong, I.S., Saura, C.A. and MacDonald, M.E. (2003) Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells. J. Biol. Chem., 278, 50514-50522.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50514-50522
-
-
Gines, S.1
Ivanova, E.2
Seong, I.S.3
Saura, C.A.4
MacDonald, M.E.5
-
16
-
-
80054772539
-
Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease
-
Chiu, C.T., Liu, G., Leeds, P. and Chuang, D.M. (2011) Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease. Neuropsychopharmacology, 36, 2406-2421.
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 2406-2421
-
-
Chiu, C.T.1
Liu, G.2
Leeds, P.3
Chuang, D.M.4
-
17
-
-
37849042536
-
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin
-
Sarkar, S., Krishna, G., Imarisio, S., Saiki, S., O'Kane, C.J. and Rubinsztein, D.C. (2008) A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. Hum. Mol. Genet., 17, 170-178.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 170-178
-
-
Sarkar, S.1
Krishna, G.2
Imarisio, S.3
Saiki, S.4
O'Kane, C.J.5
Rubinsztein, D.C.6
-
18
-
-
0034703869
-
Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells
-
Trettel, F., Rigamonti, D., Hilditch-Maguire, P., Wheeler, V.C., Sharp, A.H., Persichetti, F., Cattaneo, E. and MacDonald, M.E. (2000) Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells. Hum. Mol. Genet., 9, 2799-2809.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2799-2809
-
-
Trettel, F.1
Rigamonti, D.2
Hilditch-Maguire, P.3
Wheeler, V.C.4
Sharp, A.H.5
Persichetti, F.6
Cattaneo, E.7
MacDonald, M.E.8
-
19
-
-
33845933438
-
Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences
-
Milakovic, T., Quintanilla, R.A. and Johnson, G.V. (2006) Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences. J. Biol. Chem., 281, 34785-34795.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 34785-34795
-
-
Milakovic, T.1
Quintanilla, R.A.2
Johnson, G.V.3
-
20
-
-
40849147435
-
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking
-
Orr, A.L., Li, S., Wang, C.E., Li, H., Wang, J., Rong, J., Xu, X., Mastroberardino, P.G., Greenamyre, J.T. and Li, X.J. (2008) N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking. J. Neurosci., 28, 2783-2792.
-
(2008)
J. Neurosci.
, vol.28
, pp. 2783-2792
-
-
Orr, A.L.1
Li, S.2
Wang, C.E.3
Li, H.4
Wang, J.5
Rong, J.6
Xu, X.7
Mastroberardino, P.G.8
Greenamyre, J.T.9
Li, X.J.10
-
21
-
-
0036327065
-
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
-
Panov, A.V., Gutekunst, C.A., Leavitt, B.R., Hayden, M.R., Burke, J.R., Strittmatter, W.J. and Greenamyre, J.T. (2002) Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. Nat. Neurosci., 5, 731-736.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 731-736
-
-
Panov, A.V.1
Gutekunst, C.A.2
Leavitt, B.R.3
Hayden, M.R.4
Burke, J.R.5
Strittmatter, W.J.6
Greenamyre, J.T.7
-
22
-
-
79952443408
-
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
-
Song, W., Chen, J., Petrilli, A., Liot, G., Klinglmayr, E., Zhou, Y., Poquiz, P., Tjong, J., Pouladi, M.A., Hayden, M.R. et al. (2011) Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat. Med., 17, 377-382.
-
(2011)
Nat. Med.
, vol.17
, pp. 377-382
-
-
Song, W.1
Chen, J.2
Petrilli, A.3
Liot, G.4
Klinglmayr, E.5
Zhou, Y.6
Poquiz, P.7
Tjong, J.8
Pouladi, M.A.9
Hayden, M.R.10
-
23
-
-
58949099388
-
Effects of overexpression of huntingtin proteins on mitochondrial integrity
-
Wang, H., Lim, P.J., Karbowski, M. and Monteiro, M.J. (2009) Effects of overexpression of huntingtin proteins on mitochondrial integrity. Hum. Mol. Genet., 18, 737-752.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 737-752
-
-
Wang, H.1
Lim, P.J.2
Karbowski, M.3
Monteiro, M.J.4
-
24
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini, L., Sathasivam, K., Seller, M., Cozens, B., Harper, A., Hetherington, C., Lawton, M., Trottier, Y., Lehrach, H., Davies, S.W. et al. (1996) Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell, 87, 493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
-
25
-
-
0029885802
-
Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation
-
Delaney, S.M. and Geiger, J.D. (1996) Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation. J. Neurosci. Methods, 64, 151-156.
-
(1996)
J. Neurosci. Methods
, vol.64
, pp. 151-156
-
-
Delaney, S.M.1
Geiger, J.D.2
-
26
-
-
84855481293
-
Early alterations of brain cellular energy homeostasis in Huntington disease models
-
Mochel, F., Durant, B., Meng, X., O'Callaghan, J., Yu, H., Brouillet, E., Wheeler, V.C., Humbert, S., Schiffmann, R. and Durr, A. (2012) Early alterations of brain cellular energy homeostasis in Huntington disease models. J. Biol. Chem., 287, 1361-1370.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 1361-1370
-
-
Mochel, F.1
Durant, B.2
Meng, X.3
O'Callaghan, J.4
Yu, H.5
Brouillet, E.6
Wheeler, V.C.7
Humbert, S.8
Schiffmann, R.9
Durr, A.10
-
27
-
-
62149136286
-
Functional imaging in Huntington's disease
-
Paulsen, J.S. (2009) Functional imaging in Huntington's disease. Exp. Neurol., 216, 272-277.
-
(2009)
Exp. Neurol.
, vol.216
, pp. 272-277
-
-
Paulsen, J.S.1
-
28
-
-
0022641113
-
Positron emission tomography in the early diagnosis of Huntington's disease
-
Hayden, M.R., Martin, W.R., Stoessl, A.J., Clark, C., Hollenberg, S., Adam, M.J., Ammann, W., Harrop, R., Rogers, J., Ruth, T. et al. (1986) Positron emission tomography in the early diagnosis of Huntington's disease. Neurology, 36, 888-894.
-
(1986)
Neurology
, vol.36
, pp. 888-894
-
-
Hayden, M.R.1
Martin, W.R.2
Stoessl, A.J.3
Clark, C.4
Hollenberg, S.5
Adam, M.J.6
Ammann, W.7
Harrop, R.8
Rogers, J.9
Ruth, T.10
-
29
-
-
0023147905
-
Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease
-
Mazziotta, J.C., Phelps, M.E., Pahl, J.J., Huang, S.C., Baxter, L.R., Riege, W.H., Hoffman, J.M., Kuhl, D.E., Lanto, A.B., Wapenski, J.A. et al. (1987) Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease. N. Engl. J. Med., 316, 357-362.
-
(1987)
N. Engl. J. Med.
, vol.316
, pp. 357-362
-
-
Mazziotta, J.C.1
Phelps, M.E.2
Pahl, J.J.3
Huang, S.C.4
Baxter, L.R.5
Riege, W.H.6
Hoffman, J.M.7
Kuhl, D.E.8
Lanto, A.B.9
Wapenski, J.A.10
-
30
-
-
84862658038
-
18F-FDG PET uptake in the pre-Huntington disease caudate affects the time-to-onset independently of CAG expansion size
-
Ciarmiello, A., Giovacchini, G., Orobello, S., Bruselli, L., Elifani, F. and Squitieri, F. (2012) 18F-FDG PET uptake in the pre-Huntington disease caudate affects the time-to-onset independently of CAG expansion size. Eur. J. Nucl. Med. Mol. Imaging, 39, 1030-1036.
-
(2012)
Eur. J. Nucl. Med. Mol. Imaging
, vol.39
, pp. 1030-1036
-
-
Ciarmiello, A.1
Giovacchini, G.2
Orobello, S.3
Bruselli, L.4
Elifani, F.5
Squitieri, F.6
-
31
-
-
84887845775
-
Decreased metabolism in the cerebral cortex in early-stage Huntington's disease: A possible biomarker of disease progression? J
-
Shin, H., Kim, M.H., Lee, S.J., Lee, K.H., Kim, M.J., Kim, J.S. and Cho, J.W. (2013) Decreased metabolism in the cerebral cortex in early-stage Huntington's disease: A possible biomarker of disease progression? J. Clin. Neurol., 9, 21-25.
-
(2013)
Clin. Neurol.
, vol.9
, pp. 21-25
-
-
Shin, H.1
Kim, M.H.2
Lee, S.J.3
Lee, K.H.4
Kim, M.J.5
Kim, J.S.6
Cho, J.W.7
-
32
-
-
0025153344
-
Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease
-
Kuwert, T., Lange, H.W., Langen, K.J., Herzog, H., Aulich, A. and Feinendegen, L.E. (1990) Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease. Brain, 113, 1405-1423.
-
(1990)
Brain
, vol.113
, pp. 1405-1423
-
-
Kuwert, T.1
Lange, H.W.2
Langen, K.J.3
Herzog, H.4
Aulich, A.5
Feinendegen, L.E.6
-
33
-
-
84859904873
-
Shaping the role of mitochondria in the pathogenesis of Huntington's disease
-
Costa, V. and Scorrano, L. (2012) Shaping the role of mitochondria in the pathogenesis of Huntington's disease. EMBO J., 31, 1853-1864.
-
(2012)
EMBO J.
, vol.31
, pp. 1853-1864
-
-
Costa, V.1
Scorrano, L.2
-
34
-
-
84855165944
-
Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease
-
Reddy, P.H. and Shirendeb, U.P. (2012) Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease. Biochim. Biophys. Acta, 1822, 101-110.
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 101-110
-
-
Reddy, P.H.1
Shirendeb, U.P.2
-
35
-
-
3543141113
-
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release
-
Choo, Y.S., Johnson, G.V., MacDonald, M., Detloff, P.J. and Lesort, M. (2004) Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release. Hum. Mol. Genet., 13, 1407-1420.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1407-1420
-
-
Choo, Y.S.1
Johnson, G.V.2
MacDonald, M.3
Detloff, P.J.4
Lesort, M.5
-
36
-
-
84888792149
-
A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin
-
Damiano, M., Diguet, E., Malgorn, C., D'Aurelio, M., Galvan, L., Petit, F., Benhaim, L., Guillermier, M., Houitte, D., Dufour, N. et al. (2013) A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin. Hum. Mol. Genet., 22, 3869-3882.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 3869-3882
-
-
Damiano, M.1
Diguet, E.2
Malgorn, C.3
D'Aurelio, M.4
Galvan, L.5
Petit, F.6
Benhaim, L.7
Guillermier, M.8
Houitte, D.9
Dufour, N.10
-
37
-
-
84855395163
-
Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease
-
Shirendeb, U.P., Calkins, M.J., Manczak, M., Anekonda, V., Dufour, B., McBride, J.L., Mao, P. and Reddy, P.H. (2012) Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease. Hum. Mol. Genet., 21, 406-420.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 406-420
-
-
Shirendeb, U.P.1
Calkins, M.J.2
Manczak, M.3
Anekonda, V.4
Dufour, B.5
McBride, J.L.6
Mao, P.7
Reddy, P.H.8
-
38
-
-
33749042331
-
Transcriptional repression of PGC-1a by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
-
Cui, L., Jeong, H., Borovecki, F., Parkhurst, C.N., Tanese, N. and Krainc, D. (2006) Transcriptional repression of PGC-1a by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell, 127, 59-69.
-
(2006)
Cell
, vol.127
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
39
-
-
77957727491
-
Modulation of energy deficiency inHuntington's disease via activation of the peroxisome proliferator-activated receptor gamma
-
Chiang, M.C., Chen, C.M., Lee, M.R., Chen, H.W., Chen, H.M., Wu, Y.S., Hung, C.H., Kang, J.J., Chang, C.P., Chang, C. et al. (2010) Modulation of energy deficiency inHuntington's disease via activation of the peroxisome proliferator-activated receptor gamma. Hum. Mol. Genet., 19, 4043-4058.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4043-4058
-
-
Chiang, M.C.1
Chen, C.M.2
Lee, M.R.3
Chen, H.W.4
Chen, H.M.5
Wu, Y.S.6
Hung, C.H.7
Kang, J.J.8
Chang, C.P.9
Chang, C.10
-
40
-
-
0037072807
-
Glycogen synthase kinase-3β inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation
-
Carmichael, J., Sugars, K.L., Bao, Y.P. and Rubinsztein, D.C. (2002) Glycogen synthase kinase-3β inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation. J. Biol. Chem., 277, 33791-33798.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33791-33798
-
-
Carmichael, J.1
Sugars, K.L.2
Bao, Y.P.3
Rubinsztein, D.C.4
-
41
-
-
73949155373
-
Mutant huntingtin and glycogen synthase kinase 3-β accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease
-
Valencia, A., Reeves, P.B., Sapp, E., Li, X., Alexander, J., Kegel, K.B., Chase, K., Aronin, N. and DiFiglia, M. (2010) Mutant huntingtin and glycogen synthase kinase 3-β accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease. J. Neurosci. Res., 88, 179-190.
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 179-190
-
-
Valencia, A.1
Reeves, P.B.2
Sapp, E.3
Li, X.4
Alexander, J.5
Kegel, K.B.6
Chase, K.7
Aronin, N.8
DiFiglia, M.9
-
42
-
-
79959781166
-
Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs
-
van Eyk, C.L., O'Keefe, L.V., Lawlor, K.T., Samaraweera, S.E., McLeod, C.J., Price, G.R., Venter, D.J. and Richards, R.I. (2011) Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs. Hum. Mol. Genet., 20, 2783-2794.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2783-2794
-
-
van Eyk, C.L.1
O'Keefe, L.V.2
Lawlor, K.T.3
Samaraweera, S.E.4
McLeod, C.J.5
Price, G.R.6
Venter, D.J.7
Richards, R.I.8
-
43
-
-
0034888287
-
Applications of theMorriswatermaze in the study of learning and memory
-
D'Hooge, R. and DeDeyn, P.P. (2001) Applications of theMorriswatermaze in the study of learning and memory. Brain Res. Brain Res. Rev., 36, 60-90.
-
(2001)
Brain Res. Brain Res. Rev.
, vol.36
, pp. 60-90
-
-
D'Hooge, R.1
DeDeyn, P.P.2
-
44
-
-
77954886545
-
Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease
-
Godin, J.D., Poizat, G., Hickey, M.A., Maschat, F. and Humbert, S. (2010) Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease. EMBO J., 29, 2433-2445.
-
(2010)
EMBO J.
, vol.29
, pp. 2433-2445
-
-
Godin, J.D.1
Poizat, G.2
Hickey, M.A.3
Maschat, F.4
Humbert, S.5
-
45
-
-
0032473355
-
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
-
Ikeda, S., Kishida, S., Yamamoto, H., Murai, H., Koyama, S. and Kikuchi, A. (1998) Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin. EMBO J., 17, 1371-1384.
-
(1998)
EMBO J.
, vol.17
, pp. 1371-1384
-
-
Ikeda, S.1
Kishida, S.2
Yamamoto, H.3
Murai, H.4
Koyama, S.5
Kikuchi, A.6
-
46
-
-
80054120586
-
The dynamic role of β-catenin in synaptic plasticity
-
Maguschak, K.A. and Ressler, K.J. (2012) The dynamic role of β-catenin in synaptic plasticity. Neuropharmacology, 62, 78-88.
-
(2012)
Neuropharmacology
, vol.62
, pp. 78-88
-
-
Maguschak, K.A.1
Ressler, K.J.2
-
47
-
-
11844297771
-
GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity
-
Yoshimura, T., Kawano, Y., Arimura, N., Kawabata, S., Kikuchi, A. and Kaibuchi, K. (2005) GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity. Cell, 120, 137-149.
-
(2005)
Cell
, vol.120
, pp. 137-149
-
-
Yoshimura, T.1
Kawano, Y.2
Arimura, N.3
Kawabata, S.4
Kikuchi, A.5
Kaibuchi, K.6
-
48
-
-
0346120150
-
Role of CRMP-2 in neuronal polarity
-
Arimura, N., Menager, C., Fukata, Y. and Kaibuchi, K. (2004) Role of CRMP-2 in neuronal polarity. J. Neurobiol., 58, 34-47.
-
(2004)
J. Neurobiol.
, vol.58
, pp. 34-47
-
-
Arimura, N.1
Menager, C.2
Fukata, Y.3
Kaibuchi, K.4
-
49
-
-
84862691413
-
Collapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status
-
Yamashita, N. and Goshima, Y. (2012) Collapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status. Mol. Neurobiol., 45, 234-246.
-
(2012)
Mol. Neurobiol.
, vol.45
, pp. 234-246
-
-
Yamashita, N.1
Goshima, Y.2
-
50
-
-
0642308228
-
Collapsin response mediator proteins (CRMPs): involvement in nervous system development and adult neurodegenerative disorders
-
Charrier, E., Reibel, S., Rogemond, V., Aguera, M., Thomasset, N. and Honnorat, J. (2003) Collapsin response mediator proteins (CRMPs): involvement in nervous system development and adult neurodegenerative disorders. Mol. Neurobiol., 28, 51-64.
-
(2003)
Mol. Neurobiol.
, vol.28
, pp. 51-64
-
-
Charrier, E.1
Reibel, S.2
Rogemond, V.3
Aguera, M.4
Thomasset, N.5
Honnorat, J.6
-
51
-
-
67149093780
-
Increased CRMP2 phosphorylation is observed in Alzheimer's disease; does this tell us anything about disease development? Curr
-
Soutar, M.P., Thornhill, P., Cole, A.R. and Sutherland, C. (2009) Increased CRMP2 phosphorylation is observed in Alzheimer's disease; does this tell us anything about disease development? Curr. Alzheimer Res., 6, 269-278.
-
(2009)
Alzheimer Res.
, vol.6
, pp. 269-278
-
-
Soutar, M.P.1
Thornhill, P.2
Cole, A.R.3
Sutherland, C.4
-
52
-
-
80053174893
-
Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders
-
Crews, L., Ruf, R., Patrick, C., Dumaop, W., Trejo-Morales, M., Achim, C.L., Rockenstein, E. and Masliah, E. (2011) Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders. Mol. Neurodegener., 6, 67.
-
(2011)
Mol. Neurodegener.
, vol.6
, pp. 67
-
-
Crews, L.1
Ruf, R.2
Patrick, C.3
Dumaop, W.4
Trejo-Morales, M.5
Achim, C.L.6
Rockenstein, E.7
Masliah, E.8
-
53
-
-
70849088180
-
An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels
-
Brittain, J.M., Piekarz, A.D., Wang, Y., Kondo, T., Cummins, T.R. and Khanna, R. (2009) An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels. J. Biol. Chem., 284, 31375-31390.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 31375-31390
-
-
Brittain, J.M.1
Piekarz, A.D.2
Wang, Y.3
Kondo, T.4
Cummins, T.R.5
Khanna, R.6
-
54
-
-
84868092963
-
Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2
-
Brittain, J.M., Wang, Y., Eruvwetere, O. and Khanna, R. (2012) Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2. FEBS Lett., 586, 3813-3818.
-
(2012)
FEBS Lett.
, vol.586
, pp. 3813-3818
-
-
Brittain, J.M.1
Wang, Y.2
Eruvwetere, O.3
Khanna, R.4
-
55
-
-
84887471411
-
II(atsm) in the SOD1G37R mouse model of amyotrophic lateral sclerosis
-
II(atsm) in the SOD1G37R mouse model of amyotrophic lateral sclerosis. Amyotroph. Lateral Scler. Fontotemporal Degener., 14, 586-590.
-
(2013)
Amyotroph. Lateral Scler. Fontotemporal Degener.
, vol.14
, pp. 586-590
-
-
McAllum, E.J.1
Lim, N.K.H.2
Hickey, J.L.3
Paterson, B.M.4
Donnelly, P.S.5
Li, Q.X.6
Barnham, K.J.7
White, A.R.8
Crouch, P.J.9
|