Hydroxypropyl cellulose stabilizes amorphous solid dispersions of the poorly water soluble drug felodipine

Carbohydrate Polymers

Volumn 112, Issue , 2014, Pages 512-519

  Sarode, Ashish L ^a,b   Malekar, Swapnil A ^a   Cote, Catherine ^c   Worthen, David R ^a,b  

^a UNIVERSITY OF RHODE ISLAND   (United States)

^b The University of Rhode Island   (United States)

^c Nisso America Inc   (United States)

Author keywords

Amorphous solid dispersion; Hot melt extrusion; Hydroxypropyl cellulose; Interaction; Stability; Supersaturation

Indexed keywords

AMORPHOUS MATERIALS; BIOCHEMISTRY; CELLULOSE; CONVERGENCE OF NUMERICAL METHODS; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSIONS; DRUG PRODUCTS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROGEN BONDS; MELT SPINNING; PHASE SEPARATION; SOLUBILITY; STABILITY; SUPERSATURATION; X RAY DIFFRACTION;

AMORPHOUS SOLID DISPERSIONS; HOT MELT EXTRUSION; HYDROGEN BONDING INTERACTIONS; HYDROXYPROPYL CELLULOSE; INTERACTION; POORLY WATER-SOLUBLE DRUGS; POWDER X RAY DIFFRACTION; SUPERSATURATED SOLUTIONS;

POLYMERS;

CELLULOSE; FELODIPINE; HYDROXYPROPYLCELLULOSE; POVIDONE; SOLUTION AND SOLUBILITY;

ANALOGS AND DERIVATIVES; CHEMISTRY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG STABILITY; INFRARED SPECTROSCOPY; PROCEDURES; SOLUBILITY; SOLUTION AND SOLUBILITY; TEMPERATURE; X RAY DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; CELLULOSE; CRYSTALLIZATION; DRUG COMPOUNDING; DRUG STABILITY; FELODIPINE; POVIDONE; SOLUBILITY; SOLUTIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE; X-RAY DIFFRACTION;

EID: 84903975644     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2014.06.039     Document Type: Article

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