The inhibition effect of high storage temperature on the recrystallization rate during dissolution of nimodipine-Kollidon VA64 solid dispersions (NM-SD) prepared by hot-melt extrusion

Journal of Pharmaceutical Sciences

Volumn 100, Issue 5, 2011, Pages 1643-1647

  Jijun, Fu ^a   Lishuang, Xu ^a   Xiaoguang, Tao ^a   Min, Su ^a   Mingming, Zhao ^a   Haibing, He ^a   Xing, Tang ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Amorphous; Dissolution; Hot melt extrusion; Nimodipine; Physical stability; Solid dispersions; Solid state stability

Indexed keywords

NIMODIPINE; POVIDONE;

ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; HIGH TEMPERATURE; MOLECULAR INTERACTION; STORAGE TEMPERATURE; X RAY DIFFRACTION;

EID: 79952237025     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22429     Document Type: Article

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