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Volumn 4, Issue , 2014, Pages

Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule

Author keywords

[No Author keywords available]

Indexed keywords

ANILINE DERIVATIVE; ANTINEOPLASTIC AGENT; CG500354; CREB1 PROTEIN, HUMAN; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN P53; THIAZOLE DERIVATIVE; TP53 PROTEIN, HUMAN;

EID: 84903974202     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep05546     Document Type: Article
Times cited : (37)

References (51)
  • 2
    • 33845671339 scopus 로고    scopus 로고
    • Analysis of gene expression and chemoresistance of CD1331cancer stem cells in glioblastoma
    • Liu, G. et al. Analysis of gene expression and chemoresistance of CD1331cancer stem cells in glioblastoma. Mol Cancer 5, 67 (2006).
    • (2006) Mol Cancer , vol.5 , pp. 67
    • Liu, G.1
  • 3
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp, R. et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10, 459-466 (2009).
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1
  • 4
    • 84884558125 scopus 로고    scopus 로고
    • Unravelling cancer stem cell potential
    • Beck, B. & Blanpain, C. Unravelling cancer stem cell potential. Nat Rev Cancer 13, 727-738 (2013).
    • (2013) Nat Rev Cancer , vol.13 , pp. 727-738
    • Beck, B.1    Blanpain, C.2
  • 5
    • 62549142705 scopus 로고    scopus 로고
    • CD133 expression by neural progenitors derived from human embryonic stem cells and its use for their prospective isolation
    • Peh, G. S., Lang, R. J., Pera, M. F. & Hawes, S. M. CD133 expression by neural progenitors derived from human embryonic stem cells and its use for their prospective isolation. Stem Cells Dev 18, 269-282 (2009).
    • (2009) Stem Cells Dev , vol.18 , pp. 269-282
    • Peh, G.S.1    Lang, R.J.2    Pera, M.F.3    Hawes, S.M.4
  • 6
    • 61649114744 scopus 로고    scopus 로고
    • CD1331adult human retinal cells remain undifferentiated in Leukaemia Inhibitory Factor (LIF)
    • Carter, D. A., Dick, A. D. Mayer, E. J. CD1331adult human retinal cells remain undifferentiated in Leukaemia Inhibitory Factor (LIF). BMC Ophthalmol 9, 1 (2009).
    • (2009) BMC Ophthalmol , vol.9 , pp. 1
    • Carter, D.A.1    Dick, A.D.2    Mayer, E.J.3
  • 9
    • 33846485093 scopus 로고    scopus 로고
    • Brain tumor stem cells: Identification and concepts
    • DOI 10.1016/j.nec.2006.10.014, PII S1042368006001306, Neural Stem Cells
    • Singh, S. & Dirks, P. B. Brain tumor stem cells: identification and concepts. Neurosurg Clin N Am 18, 31-38, viii (2007). (Pubitemid 46161197)
    • (2007) Neurosurgery Clinics of North America , vol.18 , Issue.1 , pp. 31-38
    • Singh, S.1    Dirks, P.B.2
  • 11
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • DOI 10.1158/0008-5472.CAN-05-2018
    • Collins, A. T., Berry, P. A., Hyde, C., Stower, M. J. & Maitland, N. J. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65, 10946-10951 (2005). (Pubitemid 41713363)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 12
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • DOI 10.1038/35102167
    • Reya, T., Morrison, S. J., Clarke, M. F. & Weissman, I. L. Stem cells, cancer, and cancer stem cells. Nature 414, 105-111 (2001). (Pubitemid 33041634)
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 16
    • 77956245743 scopus 로고    scopus 로고
    • Integrin alpha 6 regulates glioblastoma stem cells
    • Lathia, J. D. et al. Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell 6, 421-432 (2010).
    • (2010) Cell Stem Cell , vol.6 , pp. 421-432
    • Lathia, J.D.1
  • 18
    • 77958510339 scopus 로고    scopus 로고
    • Acute promyelocytic leukaemia: Novel insights into the mechanisms of cure
    • de The, H. & Chen, Z. Acute promyelocytic leukaemia: novel insights into the mechanisms of cure. Nat Rev Cancer 10, 775-783 (2010).
    • (2010) Nat Rev Cancer , vol.10 , pp. 775-783
    • De The, H.1    Chen, Z.2
  • 19
    • 57349152259 scopus 로고    scopus 로고
    • Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation
    • Nasr, R. et al. Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation. Nat Med 14, 1333-1342 (2008).
    • (2008) Nat Med , vol.14 , pp. 1333-1342
    • Nasr, R.1
  • 20
    • 0037131973 scopus 로고    scopus 로고
    • In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia
    • Guillemin, M. C. et al. In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia. J Exp Med 196, 1373-1380 (2002).
    • (2002) J Exp Med , vol.196 , pp. 1373-1380
    • Guillemin, M.C.1
  • 21
    • 59449107942 scopus 로고    scopus 로고
    • Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression
    • Goldhoff, P. et al. Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression. Clin Cancer Res 14, 7717-7725 (2008).
    • (2008) Clin Cancer Res , vol.14 , pp. 7717-7725
    • Goldhoff, P.1
  • 22
    • 33846670549 scopus 로고    scopus 로고
    • Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo
    • DOI 10.1158/0008-5472.CAN-06-2762
    • Yang, L., Jackson, E., Woerner, B. M., Perry, A., Piwnica-Worms, D. & Rubin, J. B. Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo. Cancer Res 67, 651-658 (2007). (Pubitemid 46192204)
    • (2007) Cancer Research , vol.67 , Issue.2 , pp. 651-658
    • Yang, L.1    Jackson, E.2    Woerner, B.M.3    Perry, A.4    Piwnica-Worms, D.5    Rubin, J.B.6
  • 23
    • 33646531617 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells
    • Moreno, M. J., Ball, M., Andrade, M. F., McDermid, A. & Stanimirovic, D. B. Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells. Glia 53, 845-857 (2006).
    • (2006) Glia , vol.53 , pp. 845-857
    • Moreno, M.J.1    Ball, M.2    Andrade, M.F.3    McDermid, A.4    Stanimirovic, D.B.5
  • 24
    • 0035845567 scopus 로고    scopus 로고
    • Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB
    • DOI 10.1073/pnas.191152098
    • Mayr, B. M., Canettieri, G. & Montminy, M. R. Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB. Proc Natl Acad SciUS A98, 10936-10941 (2001). (Pubitemid 32878722)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.19 , pp. 10936-10941
    • Mayr, B.M.1    Canettieri, G.2    Montminy, M.R.3
  • 25
    • 0035430282 scopus 로고    scopus 로고
    • Transcriptional regulation by the phosphorylation-dependent factor creb
    • DOI 10.1038/35085068
    • Mayr, B. & Montminy, M. Transcriptional regulation by the phosphorylationdependent factor CREB. Nat Rev Mol Cell Biol 2, 599-609 (2001). (Pubitemid 33674011)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.8 , pp. 599-609
    • Mayr, B.1    Montminy, M.2
  • 29
    • 79958752730 scopus 로고    scopus 로고
    • 8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanisms
    • Lucchi, S., Calebiro, D., de Filippis, T., Grassi, E. S., Borghi, M. O. & Persani, L. 8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanisms. PLoS One 6, e20785 (2011).
    • (2011) PLoS One , vol.6
    • Lucchi, S.1    Calebiro, D.2    De Filippis, T.3    Grassi, E.S.4    Borghi, M.O.5    Persani, L.6
  • 30
    • 0024404145 scopus 로고
    • GTPase inhibiting mutations activate the α chain of G(s) and stimulate adenylyl cyclase in human pituitary tumours
    • DOI 10.1038/340692a0
    • Landis, C. A., Masters, S. B., Spada, A., Pace, A. M., Bourne, H. R. & Vallar, L. GTPase inhibitingmutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 340, 692-696 (1989). (Pubitemid 19214389)
    • (1989) Nature , vol.340 , Issue.6236 , pp. 692-696
    • Landis, C.A.1    Masters, S.B.2    Spada, A.3    Pace, A.M.4    Bourne, H.R.5    Vallar, L.6
  • 31
    • 0033812849 scopus 로고    scopus 로고
    • Mutations of the gene encoding the protein kinase A type Ialpha regulatory subunit in patients with the Carney complex
    • Kirschner, L. S. et al. Mutations of the gene encoding the protein kinase A type Ialpha regulatory subunit in patients with the Carney complex. Nat Genet 26, 89-92 (2000).
    • (2000) Nat Genet , vol.26 , pp. 89-92
    • Kirschner, L.S.1
  • 35
    • 0029984437 scopus 로고    scopus 로고
    • Acute administration of a permeant analog of cAMP and a phosphodiesterase inhibitor improve long-term habituation in the crab Chasmagnathus
    • DOI 10.1016/0166-4328(96)00179-9
    • Romano, A., Delorenzi, A., Pedreira, M. E., Tomsic, D. & Maldonado, H. Acute administration of a permeant analog of cAMP and a phosphodiesterase inhibitor improve long-term habituation in the crab Chasmagnathus. Behav Brain Res 75, 119-125 (1996). (Pubitemid 26076747)
    • (1996) Behavioural Brain Research , vol.75 , Issue.1-2 , pp. 119-125
    • Romano, A.1    Delorenzi, A.2    Pedreira, M.E.3    Tomsic, D.4    Maldonado, H.5
  • 36
    • 0021326159 scopus 로고
    • Brain cAMP response to phosphodiesterase inhibitors in rats killed by microwave irradiation or decapitation
    • DOI 10.1016/0006-2952(84)90295-8
    • Schneider, H. H. Brain cAMP response to phosphodiesterase inhibitors in rats killed by microwave irradiation or decapitation. Biochem Pharmacol 33, 1690-1693 (1984). (Pubitemid 14147798)
    • (1984) Biochemical Pharmacology , vol.33 , Issue.10 , pp. 1690-1693
    • Schneider, H.H.1
  • 37
    • 84863011114 scopus 로고    scopus 로고
    • Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting CAMP phosphodiesterases
    • Park, S. J. et al. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell 148, 421-433 (2012).
    • (2012) Cell , vol.148 , pp. 421-433
    • Park, S.J.1
  • 38
    • 78650891913 scopus 로고    scopus 로고
    • Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling
    • Li, Y. F. et al. Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling. J Neurosci 31, 172-183 (2011).
    • (2011) J Neurosci , vol.31 , pp. 172-183
    • Li, Y.F.1
  • 39
    • 0032803362 scopus 로고    scopus 로고
    • Induction of gap junctional intercellular communication, connexin43 expression, and subsequent differentiation in human fetal neuronal cells by stimulation of the cyclic AMP pathway
    • Dowling-Warriner, C. V. & Trosko, J. E. Induction of gap junctional intercellular communication, connexin43 expression, and subsequent differentiation in human fetal neuronal cells by stimulation of the cyclic AMP pathway. Neuroscience 95, 859-868 (2000).
    • (2000) Neuroscience , vol.95 , pp. 859-868
    • Dowling-Warriner, C.V.1    Trosko, J.E.2
  • 40
    • 0037443097 scopus 로고    scopus 로고
    • PDE4 cAMP phosphodiesterases: Modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization
    • DOI 10.1042/BJ20021698
    • Houslay, M. D. & Adams, D. R. PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. Biochem J 370, 1-18 (2003). (Pubitemid 36259414)
    • (2003) Biochemical Journal , vol.370 , Issue.1 , pp. 1-18
    • Houslay, M.D.1    Adams, D.R.2
  • 41
    • 0033783798 scopus 로고    scopus 로고
    • Cyclic 39, 59-nucleotide phosphodiesterases: Potential targets for anticancer therapy
    • Marko, D., Pahlke, G., Merz, K. H. & Eisenbrand, G. Cyclic 39, 59-nucleotide phosphodiesterases: potential targets for anticancer therapy. Chem Res Toxicol 13, 944-948 (2000).
    • (2000) Chem Res Toxicol , vol.13 , pp. 944-948
    • Marko, D.1    Pahlke, G.2    Merz, K.H.3    Eisenbrand, G.4
  • 43
    • 42449114966 scopus 로고    scopus 로고
    • Transcriptional control of human p53-regulated genes
    • DOI 10.1038/nrm2395, PII NRM2395
    • Riley, T., Sontag, E., Chen, P. & Levine, A. Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol 9, 402-412 (2008). (Pubitemid 351574202)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.5 , pp. 402-412
    • Riley, T.1    Sontag, E.2    Chen, P.3    Levine, A.4
  • 44
    • 78650153633 scopus 로고    scopus 로고
    • Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
    • Ricci-Vitiani, L. et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 468, 824-828 (2010).
    • (2010) Nature , vol.468 , pp. 824-828
    • Ricci-Vitiani, L.1
  • 45
    • 84863221153 scopus 로고    scopus 로고
    • Neoplastic cells are a rare component in human glioblastoma micro vasculature
    • Rodriguez, F. J., Orr, B. A., Ligon, K. L. & Eberhart, C. G. Neoplastic cells are a rare component in human glioblastoma microvasculature. Oncotarget 3, 98-106 (2012).
    • (2012) Oncotarget , vol.3 , pp. 98-106
    • Rodriguez, F.J.1    Orr, B.A.2    Ligon, K.L.3    Eberhart, C.G.4
  • 46
    • 54549095950 scopus 로고    scopus 로고
    • P53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
    • Zheng, H. et al. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature 455, 1129-1133 (2008).
    • (2008) Nature , vol.455 , pp. 1129-1133
    • Zheng, H.1
  • 47
    • 79952509861 scopus 로고    scopus 로고
    • Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain
    • Chow, L. M. et al. Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain. Cancer Cell 19, 305-316 (2011).
    • (2011) Cancer Cell , vol.19 , pp. 305-316
    • Chow, L.M.1
  • 48
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak, R. G. et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17, 98-110 (2010).
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1
  • 49
    • 0028322193 scopus 로고
    • Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors
    • DOI 10.1016/0955-0674(94)90035-3
    • Karin, M. Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors. Curr Opin Cell Biol 6, 415-424 (1994). (Pubitemid 24170014)
    • (1994) Current Opinion in Cell Biology , vol.6 , Issue.3 , pp. 415-424
    • Karin, M.1
  • 50
    • 79953191123 scopus 로고    scopus 로고
    • Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation
    • Copsel, S. et al. Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation. J Biol Chem 286, 6979-6988 (2011).
    • (2011) J Biol Chem , vol.286 , pp. 6979-6988
    • Copsel, S.1


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