In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia

Journal of Experimental Medicine

Volumn 196, Issue 10, 2002, Pages 1373-1380

  Guillemin, Marie Claude ^a   Raffoux, Emmanuel ^b   Vitoux, Dominique ^a   Kogan, Scott ^g   Soilihi, Hassane ^a   Lallemand Breitenbach, Valarie ^a   Zhu, Jun ^a   Janin, Anne ^c   Daniel, Marie Thérèse ^d   Gourmel, Bernard ^e   Degos, Laurent ^b   Dombret, Hervé ^b   Lanotte, Michel ^f   De Thé, Hugues ^a,e  

^a CNRS   (France)

^b Serv Clinique des Maladies du Sang   (France)

^c ERM 0220   (France)

^d Serv d'Hematologie Biologique   (France)

^e AP HP   (France)

^f SAINT LOUIS HOSPITAL   (France)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Arsenic; Clinical trial; Retinoic acid; Theophylline; Transgenic mice

Indexed keywords

8 CHLOROADENOSINE 3',5' PHOSPHATE; CYCLIC AMP;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CANCER INHIBITION; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMATIN STRUCTURE; CHROMOSOME TRANSLOCATION; HEMATOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; RISK BENEFIT ANALYSIS; TRANSCRIPTION REGULATION; TUMOR GROWTH;

ANIMALS; ARSENICALS; CELL DIFFERENTIATION; CELL DIVISION; CYCLIC AMP; LEUKEMIA, PROMYELOCYTIC, ACUTE; MICE; MICE, TRANSGENIC; OXIDES; SIGNAL TRANSDUCTION; THEOPHYLLINE; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0037131973     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021129     Document Type: Article

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