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Volumn 74, Issue 2, 2014, Pages 172-187

The role of serotonin in the control of locomotor movements and strategies for restoring locomotion after spinal cord injury

Author keywords

5 HT; Intraspinal grafting; Locomotion; Spinal cord injury

Indexed keywords

SEROTONIN;

EID: 84903942442     PISSN: 00651400     EISSN: 16890035     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (46)

References (96)
  • 1
    • 20444461041 scopus 로고    scopus 로고
    • Long-lasting recovery of locomotor function in chronic spinal rat following chronic combined pharmacological stimulation of serotonergic receptors with 8-OHDPAT and quipazine
    • Antri M, Barthe J Y, Mouffle C, Orsal D (2005) Long-lasting recovery of locomotor function in chronic spinal rat following chronic combined pharmacological stimulation of serotonergic receptors with 8-OHDPAT and quipazine. Neurosci Lett 384: 162-167.
    • (2005) Neurosci Lett , vol.384 , pp. 162-167
    • Antri, M.1    Barthe, J.Y.2    Mouffle, C.3    Orsal, D.4
  • 2
    • 0242624534 scopus 로고    scopus 로고
    • 5-HT1A receptors are involved in short- and long-term processes responsible for 5-HT-induced locomotor function recovery in chronic spinal rat
    • Antri M, Mouffle C, Orsal D, Barthe JY (2003) 5-HT1A receptors are involved in short- and long-term processes responsible for 5-HT-induced locomotor function recovery in chronic spinal rat. Eur J Neurosci 18: 1963-1972.
    • (2003) Eur J Neurosci , vol.18 , pp. 1963-1972
    • Antri, M.1    Mouffle, C.2    Orsal, D.3    Barthe, J.Y.4
  • 3
    • 0036460098 scopus 로고    scopus 로고
    • Locomotor recovery in the chronic spinal rat: Effects of long-term treatment with a 5-HT2 agonist
    • Antri M, Orsal D, Barthe JY (2002) Locomotor recovery in the chronic spinal rat: effects of long-term treatment with a 5-HT2 agonist. Eur J Neurosci 16: 467-476.
    • (2002) Eur J Neurosci , vol.16 , pp. 467-476
    • Antri, M.1    Orsal, D.2    Barthe, J.Y.3
  • 4
    • 84855294084 scopus 로고    scopus 로고
    • Projections and interconnections of genetically defined serotonin neurons in mice
    • Bang SJ, Jensen P, Dymecki SM, Commons KG (2012) Projections and interconnections of genetically defined serotonin neurons in mice. Eur J Neurosci 35: 85-96.
    • (2012) Eur J Neurosci , vol.35 , pp. 85-96
    • Bang, S.J.1    Jensen, P.2    Dymecki, S.M.3    Commons, K.G.4
  • 6
    • 0032494712 scopus 로고    scopus 로고
    • Serotonin-induced inhibition of locomotor rhythm of the rat isolated spinal cord is mediated by the 5-HT1 receptor class
    • Beato M, Nistri A (1998) Serotonin-induced inhibition of locomotor rhythm of the rat isolated spinal cord is mediated by the 5-HT1 receptor class. Proc Biol Sci 265: 2073-2080.
    • (1998) Proc Biol Sci , vol.265 , pp. 2073-2080
    • Beato, M.1    Nistri, A.2
  • 7
    • 72549109502 scopus 로고    scopus 로고
    • Strategies to restore motor functions after spinal cord injury
    • Boulenguez P, Vinay L (2009) Strategies to restore motor functions after spinal cord injury. Curr Opin Neurobiol 19: 587-600.
    • (2009) Curr Opin Neurobiol , vol.19 , pp. 587-600
    • Boulenguez, P.1    Vinay, L.2
  • 8
    • 84883716095 scopus 로고    scopus 로고
    • Lhx3-Chx10 reticu-lospinal neurons in locomotor circuits
    • Bretzner F, Brownstone RM (2013) Lhx3-Chx10 reticu-lospinal neurons in locomotor circuits. J Neurosci 33: 14681-14692.
    • (2013) J Neurosci , vol.33 , pp. 14681-14692
    • Bretzner, F.1    Brownstone, R.M.2
  • 10
    • 33644854747 scopus 로고    scopus 로고
    • Cholinergic and sero-tonergic excitation of ascending commissural neurons in the thoraco-lumbar spinal cord of the neonatal mouse
    • Carlin KP, Dai Y, Jordan LM (2006) Cholinergic and sero-tonergic excitation of ascending commissural neurons in the thoraco-lumbar spinal cord of the neonatal mouse. J Neurophysiol 95: 1278-1284.
    • (2006) J Neurophysiol , vol.95 , pp. 1278-1284
    • Carlin, K.P.1    Dai, Y.2    Jordan, L.M.3
  • 11
    • 28644451778 scopus 로고    scopus 로고
    • Molecular genetics of the early development of hindbrain serotonergic neurons
    • Cordes SP (2005) Molecular genetics of the early development of hindbrain serotonergic neurons. Clin Genet 68: 487-494.
    • (2005) Clin Genet , vol.68 , pp. 487-494
    • Cordes, S.P.1
  • 13
    • 19344371531 scopus 로고    scopus 로고
    • Localization of spinal neurons activated during locomotion using the c-fos immunohistochemical method
    • Dai X, Noga BR, Douglas JR, Jordan LM (2005) Localization of spinal neurons activated during locomotion using the c-fos immunohistochemical method. J Neurophysiol 93: 3442-3452.
    • (2005) J Neurophysiol , vol.93 , pp. 3442-3452
    • Dai, X.1    Noga, B.R.2    Douglas, J.R.3    Jordan, L.M.4
  • 14
    • 71949116311 scopus 로고    scopus 로고
    • Electrophysiological and pharmacological properties of locomotor activity-related neurons in cfos-EGFP mice
    • Dai Y, Carlin KP, Li Z, McMahon DG, Brownstone RM, Jordan LM (2009) Electrophysiological and pharmacological properties of locomotor activity-related neurons in cfos-EGFP mice. J Neurophysiol 102: 3365-3383.
    • (2009) J Neurophysiol , vol.102 , pp. 3365-3383
    • Dai, Y.1    Carlin, K.P.2    Li, Z.3    McMahon, D.G.4    Brownstone, R.M.5    Jordan, L.M.6
  • 16
    • 0035003187 scopus 로고    scopus 로고
    • The motor output and behavior produced by rhythmogenic sacrocaudal networks in spinal cords of neonatal rats
    • Delvolve I, Gabbay H, Lev-Tov A (2001) The motor output and behavior produced by rhythmogenic sacrocaudal networks in spinal cords of neonatal rats. J Neurophysiol 85: 2100-2110.
    • (2001) J Neurophysiol , vol.85 , pp. 2100-2110
    • Delvolve, I.1    Gabbay, H.2    Lev-Tov, A.3
  • 19
    • 33845526072 scopus 로고    scopus 로고
    • The evolution of walking-related outcomes over the first 12 weeks of rehabilitation for incomplete traumatic spinal cord injury: The multicenter randomized Spinal Cord Injury Locomotor Trial
    • Dobkin B, Barbeau H, Deforge D, Ditunno J, Elashoff R, Apple D, Basso M, Behrman A, Harkema S, Saulino M, Scott M (2007) The evolution of walking-related outcomes over the first 12 weeks of rehabilitation for incomplete traumatic spinal cord injury: the multicenter randomized Spinal Cord Injury Locomotor Trial. Neurorehabil Neural Repair 21: 25-35.
    • (2007) Neurorehabil Neural Repair , vol.21 , pp. 25-35
    • Dobkin, B.1    Barbeau, H.2    Deforge, D.3    Ditunno, J.4    Elashoff, R.5    Apple, D.6    Basso, M.7    Behrman, A.8    Harkema, S.9    Saulino, M.10    Scott, M.11
  • 20
    • 77954593040 scopus 로고    scopus 로고
    • A chemical-genetic approach for precise spatio-temporal control of cellular signaling
    • Dong S, Allen JA, Farrell M, Roth BL (2010) A chemical-genetic approach for precise spatio-temporal control of cellular signaling. Mol Biosyst 6: 1376-1380.
    • (2010) Mol Biosyst , vol.6 , pp. 1376-1380
    • Dong, S.1    Allen, J.A.2    Farrell, M.3    Roth, B.L.4
  • 21
    • 73549103613 scopus 로고    scopus 로고
    • Endogenous extracellular serotonin modulates the spinal locomotor network of the neonatal mouse
    • Dunbar MJ, Tran MA, Whelan PJ (2010) Endogenous extracellular serotonin modulates the spinal locomotor network of the neonatal mouse. J Physiol 588: 139-156.
    • (2010) J Physiol , vol.588 , pp. 139-156
    • Dunbar, M.J.1    Tran, M.A.2    Whelan, P.J.3
  • 22
    • 84861092003 scopus 로고    scopus 로고
    • Subarachnoid transplant of the human neuronal hNT2.19 serotonergic cell line attenuates behavioral hypersensi-tivity without affecting motor dysfunction after severe contusive spinal cord injury
    • 2011
    • Eaton MJ, Widerstrom-Noga E, Wolfe SQ (2011) Subarachnoid transplant of the human neuronal hNT2.19 serotonergic cell line attenuates behavioral hypersensi-tivity without affecting motor dysfunction after severe contusive spinal cord injury. Neurol Res Int 2011: 891605.
    • (2011) Neurol Res Int , pp. 891605
    • Eaton, M.J.1    Widerstrom-Noga, E.2    Wolfe, S.Q.3
  • 25
    • 78650895143 scopus 로고    scopus 로고
    • Locomotion after spinal cord injury depends on constitutive activity in serotonin receptors
    • Fouad K, Rank MM, Vavrek R, Murray KC, Sanelli L, Bennett DJ (2010) Locomotion after spinal cord injury depends on constitutive activity in serotonin receptors. J Neurophysiol 104: 2975-2984.
    • (2010) J Neurophysiol , vol.104 , pp. 2975-2984
    • Fouad, K.1    Rank, M.M.2    Vavrek, R.3    Murray, K.C.4    Sanelli, L.5    Bennett, D.J.6
  • 26
    • 84903964868 scopus 로고    scopus 로고
    • Grafted embryonic motoneurons contribute to the coordinated functional improvement of denervated hindlimbs after motoneuron loss induced by ventral root avulsion
    • 132.05
    • Gal L, Pajer K, Nógrádi A, Sławińska U (2012) Grafted embryonic motoneurons contribute to the coordinated functional improvement of denervated hindlimbs after motoneuron loss induced by ventral root avulsion. FENS Abstract, Vol. 6, p.132.05
    • (2012) FENS Abstract , vol.6
    • Gal, L.1    Pajer, K.2    Nógrádi, A.3    Sławińska, U.4
  • 27
    • 34247165444 scopus 로고    scopus 로고
    • Functional motoneurons develop from human neural stem cell transplants in adult rats
    • Gao J, Coggeshall RE, Chung JM, Wang J, Wu P (2007) Functional motoneurons develop from human neural stem cell transplants in adult rats. Neuroreport 18: 565-569.
    • (2007) Neuroreport , vol.18 , pp. 565-569
    • Gao, J.1    Coggeshall, R.E.2    Chung, J.M.3    Wang, J.4    Wu, P.5
  • 28
    • 13544273269 scopus 로고    scopus 로고
    • Human neural stem cell-derived cholinergic neurons innervate muscle in motoneuron deficient adult rats
    • Gao J, Coggeshall RE, Tarasenko YI, Wu P (2005) Human neural stem cell-derived cholinergic neurons innervate muscle in motoneuron deficient adult rats. Neuroscience 131: 257-262.
    • (2005) Neuroscience , vol.131 , pp. 257-262
    • Gao, J.1    Coggeshall, R.E.2    Tarasenko, Y.I.3    Wu, P.4
  • 29
    • 38649111042 scopus 로고    scopus 로고
    • Epidural stimulation: Comparison of the spinal circuits that generate and control locomotion in rats, cats and humans
    • Gerasimenko Y, Roy RR, Edgerton VR (2008) Epidural stimulation: comparison of the spinal circuits that generate and control locomotion in rats, cats and humans. Exp Neurol 209: 417-425.
    • (2008) Exp Neurol , vol.209 , pp. 417-425
    • Gerasimenko, Y.1    Roy, R.R.2    Edgerton, V.R.3
  • 30
    • 0034235758 scopus 로고    scopus 로고
    • Activation of locomotion in adult chronic spinal rats is achieved by transplantation of embryonic raphe cells reinnervating a precise lumbar level
    • Gimenez, Ribotta M, Provencher J, Feraboli-Lohnherr D, Rossignol S, Privat A, Orsal D (2000) Activation of locomotion in adult chronic spinal rats is achieved by transplantation of embryonic raphe cells reinnervating a precise lumbar level. J. Neurosci. 20: 5144-5152.
    • (2000) J. Neurosci , vol.20 , pp. 5144-5152
    • Gimenez, R.M.1    Provencher, J.2    Feraboli-Lohnherr, D.3    Rossignol, S.4    Privat, A.5    Orsal, D.6
  • 31
    • 33751527187 scopus 로고    scopus 로고
    • Monoaminergic control of cauda-equina-evoked locomotion in the neonatal mouse spinal cord
    • Gordon IT, Whelan PJ (2006) Monoaminergic control of cauda-equina-evoked locomotion in the neonatal mouse spinal cord. J Neurophysiol 96: 3122-3129.
    • (2006) J Neurophysiol , vol.96 , pp. 3122-3129
    • Gordon, I.T.1    Whelan, P.J.2
  • 32
    • 79954601076 scopus 로고    scopus 로고
    • Effects on locomotion, muscle, bone, and blood induced by a combination therapy eliciting weight-bearing stepping in nonassisted spinal cord-transected mice
    • Guertin PA, Ung RV, Rouleau P, Steuer I (2011) Effects on locomotion, muscle, bone, and blood induced by a combination therapy eliciting weight-bearing stepping in nonassisted spinal cord-transected mice. Neurorehabil Neural Repair 25: 234-242.
    • (2011) Neurorehabil Neural Repair , vol.25 , pp. 234-242
    • Guertin, P.A.1    Ung, R.V.2    Rouleau, P.3    Steuer, I.4
  • 33
    • 75549086090 scopus 로고    scopus 로고
    • Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion
    • Hagglund M, Borgius L, Dougherty KJ, Kiehn O (2010) Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion. Nat Neurosci 13: 246-252.
    • (2010) Nat Neurosci , vol.13 , pp. 246-252
    • Hagglund, M.1    Borgius, L.2    Dougherty, K.J.3    Kiehn, O.4
  • 34
    • 79958092638 scopus 로고    scopus 로고
    • Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: A case study
    • Harkema S, Gerasimenko Y, Hodes J, Burdick J, Angeli C, Chen Y, Ferreira C, Willhite A, Rejc E, Grossman RG, Edgerton VR (2011) Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study. Lancet 377: 1938-1947.
    • (2011) Lancet , vol.377 , pp. 1938-1947
    • Harkema, S.1    Gerasimenko, Y.2    Hodes, J.3    Burdick, J.4    Angeli, C.5    Chen, Y.6    Ferreira, C.7    Willhite, A.8    Rejc, E.9    Grossman, R.G.10    Edgerton, V.R.11
  • 35
    • 79955747773 scopus 로고    scopus 로고
    • The unusual response of sero-tonergic neurons after CNS Injury: Lack of axonal dieback and enhanced sprouting within the inhibitory environment of the glial scar
    • Hawthorne AL, Hu H, Kundu B, Steinmetz MP, Wylie CJ, Deneris ES, Silver J (2011) The unusual response of sero-tonergic neurons after CNS Injury: lack of axonal dieback and enhanced sprouting within the inhibitory environment of the glial scar. J Neurosci 31: 5605-5616.
    • (2011) J Neurosci , vol.31 , pp. 5605-5616
    • Hawthorne, A.L.1    Hu, H.2    Kundu, B.3    Steinmetz, M.P.4    Wylie, C.J.5    Deneris, E.S.6    Silver, J.7
  • 37
    • 36849014500 scopus 로고    scopus 로고
    • Shay BL (2001) 5-HT receptors and the neuromodualatory control of spinal cord function
    • (Cope TC, Ed). CRC Press, New York, N Y
    • Hochman S, Garraway SM, Machacek DW, Shay BL (2001) 5-HT receptors and the neuromodualatory control of spinal cord function. In: Motor Neurobiology of the Spinal Cord (Cope TC, Ed). CRC Press, New York, N Y, p. 48-87.
    • Motor Neurobiology of the Spinal Cord , pp. 48-87
    • Hochman, S.1    Garraway, S.M.2    Machacek, D.W.3
  • 38
    • 20444402656 scopus 로고    scopus 로고
    • Hindlimb stepping movements in complete spinal rats induced by epidural spinal cord stimulation
    • Ichiyama RM, Gerasimenko YP, Zhong H, Roy RR, Edgerton VR (2005) Hindlimb stepping movements in complete spinal rats induced by epidural spinal cord stimulation. Neurosci Lett 383: 339-344.
    • (2005) Neurosci Lett , vol.383 , pp. 339-344
    • Ichiyama, R.M.1    Gerasimenko, Y.P.2    Zhong, H.3    Roy, R.R.4    Edgerton, V.R.5
  • 39
    • 0032529351 scopus 로고    scopus 로고
    • Transplanted olfactory ensheathing cells remyelinate and enhance axonal conduction in the demyeli-nated dorsal columns of the rat spinal cord
    • Imaizumi T, Lankford KL, Waxman SG, Greer CA, Kocsis JD (1998) Transplanted olfactory ensheathing cells remyelinate and enhance axonal conduction in the demyeli-nated dorsal columns of the rat spinal cord. J Neurosci 18: 6176-6185.
    • (1998) J Neurosci , vol.18 , pp. 6176-6185
    • Imaizumi, T.1    Lankford, K.L.2    Waxman, S.G.3    Greer, C.A.4    Kocsis, J.D.5
  • 41
    • 36749061303 scopus 로고    scopus 로고
    • Descending command systems for the initiation of locomotion in mammals
    • Jordan LM, Liu J, Hedlund PB, Akay T, Pearson KG (2008) Descending command systems for the initiation of locomotion in mammals. Brain Res Rev 57: 183-191.
    • (2008) Brain Res Rev , vol.57 , pp. 183-191
    • Jordan, L.M.1    Liu, J.2    Hedlund, P.B.3    Akay, T.4    Pearson, K.G.5
  • 43
    • 79951665902 scopus 로고    scopus 로고
    • Chapter 12--modulation of rhythmic movement: Control of coordination
    • Jordan LM, Sławińska U (2011) Chapter 12--modulation of rhythmic movement: control of coordination. Prog Brain Res 188: 181-195.
    • (2011) Prog Brain Res , vol.188 , pp. 181-195
    • Jordan, L.M.1    Sławińska, U.2
  • 44
    • 0036976969 scopus 로고    scopus 로고
    • Electromyographic activity associated with spontaneous functional recovery after spinal cord injury in rats
    • Kaegi S, Schwab ME, Dietz V, Fouad K (2001) Electromyographic activity associated with spontaneous functional recovery after spinal cord injury in rats. Eur J Neurosci 16: 249-258.
    • (2001) Eur J Neurosci , vol.16 , pp. 249-258
    • Kaegi, S.1    Schwab, M.E.2    Dietz, V.3    Fouad, K.4
  • 45
    • 18644384444 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remy-elinate and restore locomotion after spinal cord injury
    • Keirstead HS, Nistor G, Bernal G, Totoiu M, Cloutier F, Sharp K, Steward O (2005) Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remy-elinate and restore locomotion after spinal cord injury. J Neurosci 25: 4694-4705.
    • (2005) J Neurosci , vol.25 , pp. 4694-4705
    • Keirstead, H.S.1    Nistor, G.2    Bernal, G.3    Totoiu, M.4    Cloutier, F.5    Sharp, K.6    Steward, O.7
  • 46
    • 0035109748 scopus 로고    scopus 로고
    • Transplantation of cryopreserved adult human Schwann cells enhances axonal conduction in demyelinated spinal cord
    • Kohama I, Lankford KL, Preiningerova J, White FA, Vollmer TL, Kocsis JD (2001) Transplantation of cryopreserved adult human Schwann cells enhances axonal conduction in demyelinated spinal cord. J Neurosci 21: 944-950.
    • (2001) J Neurosci , vol.21 , pp. 944-950
    • Kohama, I.1    Lankford, K.L.2    Preiningerova, J.3    White, F.A.4    Vollmer, T.L.5    Kocsis, J.D.6
  • 47
    • 77049099987 scopus 로고    scopus 로고
    • Robust upregulation of serotonin 2A receptors after chronic spinal transection of rats: An immunohistochemical study
    • Kong XY, Wienecke J, Hultborn H, Zhang M (2010) Robust upregulation of serotonin 2A receptors after chronic spinal transection of rats: an immunohistochemical study. Brain Res 1320: 60-68.
    • (2010) Brain Res , vol.1320 , pp. 60-68
    • Kong, X.Y.1    Wienecke, J.2    Hultborn, H.3    Zhang, M.4
  • 48
    • 79952003902 scopus 로고    scopus 로고
    • The time course of serotonin 2A receptor expression after spinal transection of rats: An immunohis-tochemical study
    • Kong XY, Wienecke J, Chen M, Hultborn H, Zhang M (2011) The time course of serotonin 2A receptor expression after spinal transection of rats: an immunohis-tochemical study. Neuroscience 177: 114-126.
    • (2011) Neuroscience , vol.177 , pp. 114-126
    • Kong, X.Y.1    Wienecke, J.2    Chen, M.3    Hultborn, H.4    Zhang, M.5
  • 49
    • 33746191363 scopus 로고    scopus 로고
    • Contribution of spinal 5-HT1A and 5-HT7 receptors to locomotor-like movement induced by 8-OH-DPAT in spinal cord-transected mice
    • Landry ES, Lapointe NP, Rouillard C, Levesque D, Hedlund PB, Guertin PA (2006) Contribution of spinal 5-HT1A and 5-HT7 receptors to locomotor-like movement induced by 8-OH-DPAT in spinal cord-transected mice. Eur. J. Neurosci. 24: 535-546.
    • (2006) Eur. J. Neurosci , vol.24 , pp. 535-546
    • Landry, E.S.1    Lapointe, N.P.2    Rouillard, C.3    Levesque, D.4    Hedlund, P.B.5    Guertin, P.A.6
  • 51
    • 0346848761 scopus 로고    scopus 로고
    • Treadmill locomotion in the intact and spinal mouse
    • Leblond H, L'Esperance M, Orsal D, Rossignol S (2003) Treadmill locomotion in the intact and spinal mouse. J Neurosci 23: 11411-11419.
    • (2003) J Neurosci , vol.23 , pp. 11411-11419
    • Leblond, H.1    L'Esperance, M.2    Orsal, D.3    Rossignol, S.4
  • 52
    • 0033973971 scopus 로고    scopus 로고
    • Sacrocaudal affer-ents induce rhythmic efferent bursting in isolated spinal cords of neonatal rats
    • Lev-Tov A, Delvolve I, Kremer E (2000) Sacrocaudal affer-ents induce rhythmic efferent bursting in isolated spinal cords of neonatal rats. J Neurophysiol 83: 888-894.
    • (2000) J Neurophysiol , vol.83 , pp. 888-894
    • Lev-Tov, A.1    Delvolve, I.2    Kremer, E.3
  • 53
    • 23044436270 scopus 로고    scopus 로고
    • Stimulation of the parapyramidal region of the neonatal rat brain stem produces locomotor-like activity involving spinal 5-HT7 and 5-HT2A receptors
    • Liu J, Jordan LM (2005) Stimulation of the parapyramidal region of the neonatal rat brain stem produces locomotor-like activity involving spinal 5-HT7 and 5-HT2A receptors. J Neurophysiol 94: 1392-1404.
    • (2005) J Neurophysiol , vol.94 , pp. 1392-1404
    • Liu, J.1    Jordan, L.M.2
  • 54
    • 67649586245 scopus 로고    scopus 로고
    • Spinal 5-HT7 receptors are critical for alternating activity during locomotion: In vitro neonatal and in vivo adult studies using 5-HT7 receptor knockout mice
    • Liu J, Akay T, Hedlund PB, Pearson KG, Jordan LM (2009) Spinal 5-HT7 receptors are critical for alternating activity during locomotion: in vitro neonatal and in vivo adult studies using 5-HT7 receptor knockout mice. J Neurophysiol 102: 337-348.
    • (2009) J Neurophysiol , vol.102 , pp. 337-348
    • Liu, J.1    Akay, T.2    Hedlund, P.B.3    Pearson, K.G.4    Jordan, L.M.5
  • 55
    • 76249116968 scopus 로고    scopus 로고
    • Exercise-induced motor improvement after complete spinal cord transection and its relation to expression of brain-derived neurotrophic factor and presynaptic markers
    • Macias M, Nowicka D, Czupryn A, Sulejczak D, Skup M, Skangiel-Kramska J, Czarkowska-Bauch J (2009) Exercise-induced motor improvement after complete spinal cord transection and its relation to expression of brain-derived neurotrophic factor and presynaptic markers. BMC Neurosci 10: 144.
    • (2009) BMC Neurosci , vol.10 , pp. 144
    • Macias, M.1    Nowicka, D.2    Czupryn, A.3    Sulejczak, D.4    Skup, M.5    Skangiel-Kramska, J.6    Czarkowska-Bauch, J.7
  • 56
    • 18844408208 scopus 로고    scopus 로고
    • Serotonin-related enhancement of recovery of hind limb motor functions in spinal rats after grafting of embryonic raphe nuclei
    • Majczyński H, Maleszak K, Cabaj A, Sławińska U (2005) Serotonin-related enhancement of recovery of hind limb motor functions in spinal rats after grafting of embryonic raphe nuclei. J. Neurotrauma 22: 590-604.
    • (2005) J. Neurotrauma , vol.22 , pp. 590-604
    • Majczyński, H.1    Maleszak, K.2    Cabaj, A.3    Sławińska, U.4
  • 57
    • 34249913930 scopus 로고    scopus 로고
    • Comparison of two methods for quantitative assessment of unrestrained locomotion in the rat
    • Majczyński H, Maleszak K, Górska T, Sławińska U (2007) Comparison of two methods for quantitative assessment of unrestrained locomotion in the rat. J Neurosci Methods 163: 197-207.
    • (2007) J Neurosci Methods , vol.163 , pp. 197-207
    • Majczyński, H.1    Maleszak, K.2    Górska, T.3    Sławińska, U.4
  • 58
    • 37349002714 scopus 로고    scopus 로고
    • Locomotor recovery after thoracic spinal cord lesions in cats, rats and humans
    • Majczyński H, Sławińska U (2007) Locomotor recovery after thoracic spinal cord lesions in cats, rats and humans. Acta Neurobiol Exp (Wars) 67: 235-257.
    • (2007) Acta Neurobiol Exp (Wars) , vol.67 , pp. 235-257
    • Majczyński, H.1    Sławińska, U.2
  • 59
    • 0020075834 scopus 로고
    • Induction of hindlimb stepping movements in rats spinally transected as adults or as neo-nates
    • Meisel RL, Rakerd B (1982) Induction of hindlimb stepping movements in rats spinally transected as adults or as neo-nates. Brain Res 240: 353-356.
    • (1982) Brain Res , vol.240 , pp. 353-356
    • Meisel, R.L.1    Rakerd, B.2
  • 60
    • 0034267376 scopus 로고    scopus 로고
    • Mini-review: Assessment of behavioural recovery following spinal cord injury in rats
    • Muir GD, Webb AA (2000) Mini-review: assessment of behavioural recovery following spinal cord injury in rats. Eur J Neurosci 12: 3079-3086.
    • (2000) Eur J Neurosci , vol.12 , pp. 3079-3086
    • Muir, G.D.1    Webb, A.A.2
  • 64
    • 84855188602 scopus 로고    scopus 로고
    • Alterations of serotonin 2C and 2A receptors in response to T10 spinal cord transection in rats
    • Navarrett S, Collier L, Cardozo C, Dracheva S (2012) Alterations of serotonin 2C and 2A receptors in response to T10 spinal cord transection in rats. Neurosci Lett 506: 74-78.
    • (2012) Neurosci Lett , vol.506 , pp. 74-78
    • Navarrett, S.1    Collier, L.2    Cardozo, C.3    Dracheva, S.4
  • 65
    • 13544264789 scopus 로고    scopus 로고
    • Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation
    • Nistor GI, Totoiu MO, Haque N, Carpenter MK, Keirstead HS (2005) Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation. Glia 49: 385-396.
    • (2005) Glia , vol.49 , pp. 385-396
    • Nistor, G.I.1    Totoiu, M.O.2    Haque, N.3    Carpenter, M.K.4    Keirstead, H.S.5
  • 66
    • 70349292169 scopus 로고    scopus 로고
    • Locomotor-activated neurons of the cat. I. Serotonergic innervation and co-localization of 5-HT7, 5-HT2A, and 5-HT1A receptors in the thoraco-lumbar spinal cord
    • Noga BR, Johnson DM, Riesgo MI, Pinzon A (2009) Locomotor-activated neurons of the cat. I. Serotonergic innervation and co-localization of 5-HT7, 5-HT2A, and 5-HT1A receptors in the thoraco-lumbar spinal cord. J Neurophysiol 102: 1560-1576.
    • (2009) J Neurophysiol , vol.102 , pp. 1560-1576
    • Noga, B.R.1    Johnson, D.M.2    Riesgo, M.I.3    Pinzon, A.4
  • 67
    • 0029957402 scopus 로고    scopus 로고
    • Improved motor function of denervated rat hindlimb muscles induced by embryonic spinal cord grafts
    • Nógrádi A, Vrbová G (1996) Improved motor function of denervated rat hindlimb muscles induced by embryonic spinal cord grafts. Eur J Neurosci 8: 2198-2203.
    • (1996) Eur J Neurosci , vol.8 , pp. 2198-2203
    • Nógrádi, A.1    Vrbová, G.2
  • 68
    • 0037336703 scopus 로고    scopus 로고
    • Reversible disorganization of the locomotor pattern after neonatal spinal cord transection in the rat
    • Norreel JC, Pflieger JF, Pearlstein E, Simeoni-Alias J, Clarac F, Vinay L (2003) Reversible disorganization of the locomotor pattern after neonatal spinal cord transection in the rat. J Neurosci 23: 1924-1932.
    • (2003) J Neurosci , vol.23 , pp. 1924-1932
    • Norreel, J.C.1    Pflieger, J.F.2    Pearlstein, E.3    Simeoni-Alias, J.4    Clarac, F.5    Vinay, L.6
  • 69
    • 0017626093 scopus 로고
    • Mnoaminergic rein-nervation of the transected spinal cord by homologous fetal brain grafts
    • Nygren LG, Olson L, Seiger A (1977) Mnoaminergic rein-nervation of the transected spinal cord by homologous fetal brain grafts. Brain Res 129: 227-235.
    • (1977) Brain Res , vol.129 , pp. 227-235
    • Nygren, L.G.1    Olson, L.2    Seiger, A.3
  • 71
    • 17144410680 scopus 로고    scopus 로고
    • Serotonin refines the locomotor-related alternations in the in vitro neonatal rat spinal cord
    • Pearlstein E, Ben Mabrouk F, Pflieger JF, Vinay L (2005) Serotonin refines the locomotor-related alternations in the in vitro neonatal rat spinal cord. Eur J Neurosci 21: 1338-1346.
    • (2005) Eur J Neurosci , vol.21 , pp. 1338-1346
    • Pearlstein, E.1    Ben Mabrouk, F.2    Pflieger, J.F.3    Vinay, L.4
  • 72
    • 79955945392 scopus 로고    scopus 로고
    • Contribution of 5-HT to locomotion - the paradox of Pet-1(-/-) mice
    • Pearlstein E, Bras H, Deneris ES, Vinay L (2011) Contribution of 5-HT to locomotion - the paradox of Pet-1(-/-) mice. Eur J. Neurosci 33: 1812-1822.
    • (2011) Eur J. Neurosci , vol.33 , pp. 1812-1822
    • Pearlstein, E.1    Bras, H.2    Deneris, E.S.3    Vinay, L.4
  • 73
    • 33646572511 scopus 로고    scopus 로고
    • Designing cell- and gene-based regeneration strategies to repair the injured spinal cord
    • Pearse DD, Bunge MB (2006) Designing cell- and gene-based regeneration strategies to repair the injured spinal cord. J Neurotrauma 23: 438-452.
    • (2006) J Neurotrauma , vol.23 , pp. 438-452
    • Pearse, D.D.1    Bunge, M.B.2
  • 75
    • 0026763068 scopus 로고
    • Fate of B1-B2 and B3 rhombencephalic cells transplanted into the transected spinal cord of adult rats: Light and electron microscopic studies
    • Rajaofetra N, Konig N, Poulat P, Marlier L, Sandillon F, Drian MJ, Geffard M, Privat A (1992) Fate of B1-B2 and B3 rhombencephalic cells transplanted into the transected spinal cord of adult rats: light and electron microscopic studies. Exp Neurol 117: 59-70.
    • (1992) Exp Neurol , vol.117 , pp. 59-70
    • Rajaofetra, N.1    Konig, N.2    Poulat, P.3    Marlier, L.4    Sandillon, F.5    Drian, M.J.6    Geffard, M.7    Privat, A.8
  • 76
    • 70449807650 scopus 로고    scopus 로고
    • Stem cells and spinal cord regeneration
    • Rossi SL, Keirstead HS (2009) Stem cells and spinal cord regeneration. Curr Opin Biotechnol 20: 552-562.
    • (2009) Curr Opin Biotechnol , vol.20 , pp. 552-562
    • Rossi, S.L.1    Keirstead, H.S.2
  • 77
    • 79959865503 scopus 로고    scopus 로고
    • Recovery of locomotion after spinal cord injury: Some facts and mechanisms
    • Rossignol S, Frigon A (2011) Recovery of locomotion after spinal cord injury: some facts and mechanisms. Annu Rev Neurosci 34: 413-440.
    • (2011) Annu Rev Neurosci , vol.34 , pp. 413-440
    • Rossignol, S.1    Frigon, A.2
  • 78
    • 0034668699 scopus 로고    scopus 로고
    • The role of serotonin in reflex modulation and locomotor rhythm production in the mammalian spinal cord
    • Schmidt BJ, Jordan LM (2000) The role of serotonin in reflex modulation and locomotor rhythm production in the mammalian spinal cord. Brain Res Bull 53: 689-710.
    • (2000) Brain Res Bull , vol.53 , pp. 689-710
    • Schmidt, B.J.1    Jordan, L.M.2
  • 81
    • 84859237934 scopus 로고    scopus 로고
    • The upright posture improves plantar stepping and alters responses to serotonergic drugs in spinal rats
    • Sławińska U, Majczyński H, Dai Y, Jordan LM (2012b) The upright posture improves plantar stepping and alters responses to serotonergic drugs in spinal rats. J Physiol (Lond.) 590: 1721-1736.
    • (2012) J Physiol (Lond.) , vol.590 , pp. 1721-1736
    • Sławińska, U.1    Majczyński, H.2    Dai, Y.3    Jordan, L.M.4
  • 82
    • 0033994465 scopus 로고    scopus 로고
    • Recovery of hindlimb motor functions after spinal cord transection is enhanced by grafts of the embryonic raphe nuclei
    • Sławińska U, Majczyński H, Djavadian R (2000) Recovery of hindlimb motor functions after spinal cord transection is enhanced by grafts of the embryonic raphe nuclei. Exp Brain Res 132: 27-38.
    • (2000) Exp Brain Res , vol.132 , pp. 27-38
    • Sławińska, U.1    Majczyński, H.2    Djavadian, R.3
  • 83
    • 84881376812 scopus 로고    scopus 로고
    • Grafting of fetal brainstem 5-HT neurons into the sublesional spinal cord of paraplegic rats restores coordinated hindlimb locomotion
    • Sławińska U, Miazga K, Cabaj AM, Leszczyńska AN, Majczyński H, Nagy JI, Jordan LM (2013) Grafting of fetal brainstem 5-HT neurons into the sublesional spinal cord of paraplegic rats restores coordinated hindlimb locomotion. Exp Neurol 247: 572-581.
    • (2013) Exp Neurol , vol.247 , pp. 572-581
    • Sławińska, U.1    Miazga, K.2    Cabaj, A.M.3    Leszczyńska, A.N.4    Majczyński, H.5    Nagy, J.I.6    Jordan, L.M.7
  • 84
    • 84867630215 scopus 로고    scopus 로고
    • Comment on Restoring voluntary control of locomotion after paralyzing spinal cord injury
    • [author reply
    • Sławińska U, Rossignol S, Bennett DJ, Schmidt BJ, Frigon A, Fouad K, Jordan LM (2012c) Comment on "Restoring voluntary control of locomotion after paralyzing spinal cord injury". Science 338: 328. [author reply p. 328]
    • (2012) Science , vol.338 , Issue.328 , pp. 328
    • Sławińska, U.1    Rossignol, S.2    Bennett, D.J.3    Schmidt, B.J.4    Frigon, A.5    Fouad, K.6    Jordan, L.M.7
  • 85
    • 0023921214 scopus 로고
    • Neural mechanisms generating locomotion studied in mammalian brain stem-spinal cord in vitro
    • Smith JC, Feldman JL, Schmidt BJ (1988) Neural mechanisms generating locomotion studied in mammalian brain stem-spinal cord in vitro. Faseb J 2: 2283-2288.
    • (1988) Faseb J , vol.2 , pp. 2283-2288
    • Smith, J.C.1    Feldman, J.L.2    Schmidt, B.J.3
  • 86
    • 0004010456 scopus 로고    scopus 로고
    • Lippincott, Williams, and Wilkins, Philadelphia, PA
    • Stedman's Medical Dictionary (2000) Lippincott, Williams, and Wilkins, Philadelphia, PA.
    • (2000) Stedman's Medical Dictionary
  • 87
    • 84867753885 scopus 로고    scopus 로고
    • Spinal cord stimulation: Therapeutic benefits and movement generation after spinal cord injury
    • Tator CH, Minassian K, Mushahwar VK (2012) Spinal cord stimulation: therapeutic benefits and movement generation after spinal cord injury. Handb Clin Neurol 109: 283-296.
    • (2012) Handb Clin Neurol , vol.109 , pp. 283-296
    • Tator, C.H.1    Minassian, K.2    Mushahwar, V.K.3
  • 88
    • 0025652414 scopus 로고
    • Anatomy of the serotonergic system
    • discussion 34-35
    • Tork I (1990) Anatomy of the serotonergic system. Ann N Y Acad Sci 600: 9-34; discussion 34-35.
    • (1990) Ann N Y Acad Sci , vol.600 , pp. 9-34
    • Tork, I.1
  • 89
    • 2342611969 scopus 로고    scopus 로고
    • Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis
    • Totoiu MO, Nistor GI, Lane TE, Keirstead HS (2004) Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis. Exp Neurol 187: 254-265.
    • (2004) Exp Neurol , vol.187 , pp. 254-265
    • Totoiu, M.O.1    Nistor, G.I.2    Lane, T.E.3    Keirstead, H.S.4
  • 90
    • 56749170806 scopus 로고    scopus 로고
    • Role of spinal 5-HT2 receptor subtypes in quipazine-induced hindlimb movements after a low-thoracic spinal cord transection
    • Ung RV, Landry ES, Rouleau P, Lapointe NP, Rouillard C, Guertin PA (2008) Role of spinal 5-HT2 receptor subtypes in quipazine-induced hindlimb movements after a low-thoracic spinal cord transection. Eur J Neurosci 28: 2231-2242.
    • (2008) Eur J Neurosci , vol.28 , pp. 2231-2242
    • Ung, R.V.1    Landry, E.S.2    Rouleau, P.3    Lapointe, N.P.4    Rouillard, C.5    Guertin, P.A.6
  • 92
    • 84903964871 scopus 로고    scopus 로고
    • Summary of strategies used to repair the injured spinal cord
    • Dimitrijevic MR, Kakulas BA, McKay WB, Vrbová G, Eds). Oxford University Press, Oxford, UK
    • Vrbová G, Sławińska U (2012) Summary of strategies used to repair the injured spinal cord. In: Restorative Neurology of Spinal Cord Injury (Dimitrijevic MR, Kakulas BA, McKay WB, Vrbová G, Eds). Oxford University Press, Oxford, UK.
    • (2012) Restorative Neurology of Spinal Cord Injury
    • Vrbová, G.1    Sławińska, U.2
  • 93
    • 0033638778 scopus 로고    scopus 로고
    • Properties of rhythmic activity generated by the isolated spinal cord of the neonatal mouse
    • Whelan P, Bonnot A, O'Donovan MJ (2000) Properties of rhythmic activity generated by the isolated spinal cord of the neonatal mouse. J Neurophysiol 84: 2821-2833.
    • (2000) J Neurophysiol , vol.84 , pp. 2821-2833
    • Whelan, P.1    Bonnot, A.2    O'Donovan, M.J.3
  • 94
    • 84870152106 scopus 로고    scopus 로고
    • Schwann cell transplantation: A repair strategy for spinal cord injury?
    • Wiliams RR, Bunge MB (2012) Schwann cell transplantation: a repair strategy for spinal cord injury? Prog Brain Res 201: 295-312.
    • (2012) Prog Brain Res , vol.201 , pp. 295-312
    • Wiliams, R.R.1    Bunge, M.B.2
  • 95
    • 77249114658 scopus 로고    scopus 로고
    • Tail nerve electrical stimulation induces body weight-supported stepping in rats with spinal cord injury
    • Zhang SX, Huang F, Gates M, White J, Holmberg EG (2010) Tail nerve electrical stimulation induces body weight-supported stepping in rats with spinal cord injury. J Neurosci Methods 187: 183-189.
    • (2010) J Neurosci Methods , vol.187 , pp. 183-189
    • Zhang, S.X.1    Huang, F.2    Gates, M.3    White, J.4    Holmberg, E.G.5
  • 96
    • 33645528869 scopus 로고    scopus 로고
    • Serotonin modulates the properties of ascending commissural interneurons in the neonatal mouse spinal cord
    • Zhong G, Diaz-Rios M, Harris-Warrick RM (2006) Serotonin modulates the properties of ascending commissural interneurons in the neonatal mouse spinal cord. J Neurophysiol 95: 1545-1555.
    • (2006) J Neurophysiol , vol.95 , pp. 1545-1555
    • Zhong, G.1    Diaz-Rios, M.2    Harris-Warrick, R.M.3


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