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Volumn 16, Issue 4, 2014, Pages 207-223

Functional analysis of limb transcriptional enhancers in the mouse

Author keywords

[No Author keywords available]

Indexed keywords

BODY SIZE; DATA SET; EMBRYONIC DEVELOPMENT; FUNCTIONAL MORPHOLOGY; GENOME; LIMB; PHENOTYPIC PLASTICITY; PROTEIN; RODENT;

EID: 84903942178     PISSN: 1520541X     EISSN: 1525142X     Source Type: Journal    
DOI: 10.1111/ede.12084     Document Type: Article
Times cited : (19)

References (65)
  • 1
    • 27544443178 scopus 로고    scopus 로고
    • Mapping cis-regulatory domains in the human genome using multi-species conservation of synteny
    • Ahituv, N., Prabhakar, S., Poulin, F., Rubin, E. M., and Couronne, O. 2005, Mapping cis-regulatory domains in the human genome using multi-species conservation of synteny. Hum. Mol. Genet. 14: 3057-3063.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 3057-3063
    • Ahituv, N.1    Prabhakar, S.2    Poulin, F.3    Rubin, E.M.4    Couronne, O.5
  • 2
    • 34548697503 scopus 로고    scopus 로고
    • Deletion of ultraconserved elements yields viable mice
    • Ahituv, N., et al. 2007, Deletion of ultraconserved elements yields viable mice. PLoS Biol. 5: e234.
    • (2007) PLoS Biol. , vol.5
    • Ahituv, N.1
  • 3
    • 84878754528 scopus 로고    scopus 로고
    • A switch between topological domains underlies HoxD genes collinearity in mouse limbs
    • Andrey, G., et al. 2013. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science 340: 1234167.
    • (2013) Science , vol.340 , pp. 1234167
    • Andrey, G.1
  • 4
    • 33845971522 scopus 로고    scopus 로고
    • Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
    • Bandyopadhyay, A., Tsuji, K., Cox, K., Harfe, B. D., Rosen, V., and Tabin, C. J. 2006. Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet. 2: e216.
    • (2006) PLoS Genet. , vol.2
    • Bandyopadhyay, A.1    Tsuji, K.2    Cox, K.3    Harfe, B.D.4    Rosen, V.5    Tabin, C.J.6
  • 5
    • 0019811465 scopus 로고
    • Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences
    • Banerji, J., Rusconi, S., and Schaffner, W. 1981. Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell 27: 299-308.
    • (1981) Cell , vol.27 , pp. 299-308
    • Banerji, J.1    Rusconi, S.2    Schaffner, W.3
  • 6
    • 0028172159 scopus 로고
    • Mullerian-inhibiting substance function during mammalian sexual development
    • Behringer, R. R., Finegold, M. J., and Cate, R. L. 1994. Mullerian-inhibiting substance function during mammalian sexual development. Cell 79: 415-425.
    • (1994) Cell , vol.79 , pp. 415-425
    • Behringer, R.R.1    Finegold, M.J.2    Cate, R.L.3
  • 7
    • 2542542256 scopus 로고    scopus 로고
    • Ultraconserved elements in the human genome
    • Bejerano, G., et al. 2004. Ultraconserved elements in the human genome. Science 304: 1321-1325.
    • (2004) Science , vol.304 , pp. 1321-1325
    • Bejerano, G.1
  • 8
    • 0034916613 scopus 로고    scopus 로고
    • p300/CBP proteins: HATs for transcriptional bridges and scaffolds
    • Chan, H. M., and La Thangue, N. B. 2001. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J. Cell. Sci. 114: 2363-2373.
    • (2001) J. Cell. Sci. , vol.114 , pp. 2363-2373
    • Chan, H.M.1    La Thangue, N.B.2
  • 9
    • 34147205885 scopus 로고    scopus 로고
    • Bmp2 transcription in osteoblast progenitors is regulated by a distant 3′ enhancer located 156.3 kilobases from the promoter
    • Chandler, R. L., Chandler, K. J., McFarland, K. A., and Mortlock, D. P. 2007. Bmp2 transcription in osteoblast progenitors is regulated by a distant 3′ enhancer located 156.3 kilobases from the promoter. Mol. Cell. Biol. 27: 2934-2951.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 2934-2951
    • Chandler, R.L.1    Chandler, K.J.2    McFarland, K.A.3    Mortlock, D.P.4
  • 10
    • 84861911346 scopus 로고    scopus 로고
    • Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb
    • Cotney, J., et al. 2012. Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb. Genome Res. 22: 1069-1080.
    • (2012) Genome Res. , vol.22 , pp. 1069-1080
    • Cotney, J.1
  • 11
    • 84879911829 scopus 로고    scopus 로고
    • The evolution of lineage-specific regulatory activities in the human embryonic limb
    • Cotney, J., et al. 2013. The evolution of lineage-specific regulatory activities in the human embryonic limb. Cell 154: 185-196.
    • (2013) Cell , vol.154 , pp. 185-196
    • Cotney, J.1
  • 13
    • 15544382841 scopus 로고    scopus 로고
    • Embryonic staging system for the short-tailed fruit bat, Carollia perspicillata, a model organism for the mammalian order Chiroptera, based upon timed pregnancies in captive-bred animals
    • Cretekos, C. J., et al. 2005. Embryonic staging system for the short-tailed fruit bat, Carollia perspicillata, a model organism for the mammalian order Chiroptera, based upon timed pregnancies in captive-bred animals. Dev. Dyn. 233: 721-738.
    • (2005) Dev. Dyn. , vol.233 , pp. 721-738
    • Cretekos, C.J.1
  • 14
    • 0029026767 scopus 로고
    • Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11
    • Davis, A. P., Witte, D. P., Hsieh-Li, H. M., Potter, S. S., and Capecchi, M. R. 1995. Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11. Nature 375: 791-795.
    • (1995) Nature , vol.375 , pp. 791-795
    • Davis, A.P.1    Witte, D.P.2    Hsieh-Li, H.M.3    Potter, S.S.4    Capecchi, M.R.5
  • 15
    • 33744912750 scopus 로고    scopus 로고
    • Frontal nasal prominence expression driven by Tcfap2a relies on a conserved binding site for STAT proteins
    • Donner, A. L., and Williams, T. 2006. Frontal nasal prominence expression driven by Tcfap2a relies on a conserved binding site for STAT proteins. Dev. Dyn. 235: 1358-1370.
    • (2006) Dev. Dyn. , vol.235 , pp. 1358-1370
    • Donner, A.L.1    Williams, T.2
  • 16
    • 37549020745 scopus 로고    scopus 로고
    • Identification and analysis of a conserved Tcfap2a intronic enhancer element required for expression in facial and limb bud mesenchyme
    • Feng, W., Huang, J., Zhang, J., and Williams, T. 2008. Identification and analysis of a conserved Tcfap2a intronic enhancer element required for expression in facial and limb bud mesenchyme. Mol. Cell. Biol. 28: 315-325.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 315-325
    • Feng, W.1    Huang, J.2    Zhang, J.3    Williams, T.4
  • 18
    • 58149163279 scopus 로고    scopus 로고
    • Shaping skeletal growth by modular regulatory elements in the Bmp5 gene
    • Guenther, C., Pantalena-Filho, L., and Kingsley, D. M. 2008. Shaping skeletal growth by modular regulatory elements in the Bmp5 gene. PLoS Genet. 4: e1000308.
    • (2008) PLoS Genet. , vol.4
    • Guenther, C.1    Pantalena-Filho, L.2    Kingsley, D.M.3
  • 19
    • 0031770816 scopus 로고    scopus 로고
    • Engineering chromosomes in mice through targeted meiotic recombination (TAMERE)
    • Herault, Y., Rassoulzadegan, M., Cuzin, F., and Duboule, D. 1998. Engineering chromosomes in mice through targeted meiotic recombination (TAMERE). Nat. Genet. 20: 381-384.
    • (1998) Nat. Genet. , vol.20 , pp. 381-384
    • Herault, Y.1    Rassoulzadegan, M.2    Cuzin, F.3    Duboule, D.4
  • 20
    • 51149097760 scopus 로고    scopus 로고
    • Shadow enhancers as a source of evolutionary novelty
    • Hong, J. W., Hendrix, D. A., and Levine, M. S. 2008. Shadow enhancers as a source of evolutionary novelty. Science 321: 1314.
    • (2008) Science , vol.321 , pp. 1314
    • Hong, J.W.1    Hendrix, D.A.2    Levine, M.S.3
  • 21
    • 4143098311 scopus 로고    scopus 로고
    • CBP and p300: HATs for different occasions
    • Kalkhoven, E. 2004. CBP and p300: HATs for different occasions. Biochem. Pharmacol. 68: 1145-1155.
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 1145-1155
    • Kalkhoven, E.1
  • 22
    • 34548406546 scopus 로고    scopus 로고
    • Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms
    • Kolpakova-Hart, E., Jinnin, M., Hou, B., Fukai, N., and Olsen, B. R. 2007. Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms. Dev. Biol. 309: 273-284.
    • (2007) Dev. Biol. , vol.309 , pp. 273-284
    • Kolpakova-Hart, E.1    Jinnin, M.2    Hou, B.3    Fukai, N.4    Olsen, B.R.5
  • 23
    • 0042810698 scopus 로고    scopus 로고
    • A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly
    • Lettice, L. A., et al. 2003. A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Hum. Mol. Genet. 12: 1725-1735.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1725-1735
    • Lettice, L.A.1
  • 24
    • 77956495708 scopus 로고    scopus 로고
    • Transcriptional enhancers in animal development and evolution
    • Levine, M. 2010. Transcriptional enhancers in animal development and evolution. Curr. Biol. 20: R754-R763.
    • (2010) Curr. Biol. , vol.20
    • Levine, M.1
  • 25
    • 0031765409 scopus 로고    scopus 로고
    • Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth
    • Li, Y., and Behringer, R. R. 1998. Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth. Nat. Genet. 20: 309-311.
    • (1998) Nat. Genet. , vol.20 , pp. 309-311
    • Li, Y.1    Behringer, R.R.2
  • 26
    • 84872258810 scopus 로고    scopus 로고
    • Genome-wide analysis reveals the unique stem cell identity of human amniocytes
    • Maguire, C. T., et al. 2013. Genome-wide analysis reveals the unique stem cell identity of human amniocytes. PLoS ONE 8: e53372.
    • (2013) PLoS ONE , vol.8
    • Maguire, C.T.1
  • 27
    • 84875249885 scopus 로고    scopus 로고
    • An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape
    • Marinic, M., Aktas, T., Ruf, S., and Spitz, F. 2013. An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape. Dev. Cell. 24: 530-542.
    • (2013) Dev. Cell. , vol.24 , pp. 530-542
    • Marinic, M.1    Aktas, T.2    Ruf, S.3    Spitz, F.4
  • 28
    • 33846082255 scopus 로고    scopus 로고
    • A series of ENU-induced single-base substitutions in a long-range cis-element altering Sonic hedgehog expression in the developing mouse limb bud
    • Masuya, H., et al. 2007. A series of ENU-induced single-base substitutions in a long-range cis-element altering Sonic hedgehog expression in the developing mouse limb bud. Genomics 89: 207-214.
    • (2007) Genomics , vol.89 , pp. 207-214
    • Masuya, H.1
  • 29
    • 50649114724 scopus 로고    scopus 로고
    • Dual hindlimb control elements in the Tbx4 gene and region-specific control of bone size in vertebrate limbs
    • Menke, D. B., Guenther, C., and Kingsley, D. M. 2008. Dual hindlimb control elements in the Tbx4 gene and region-specific control of bone size in vertebrate limbs. Development 135: 2543-2553.
    • (2008) Development , vol.135 , pp. 2543-2553
    • Menke, D.B.1    Guenther, C.2    Kingsley, D.M.3
  • 30
    • 81855227640 scopus 로고    scopus 로고
    • A regulatory archipelago controls Hox genes transcription in digits
    • Montavon, T., et al. 2011. A regulatory archipelago controls Hox genes transcription in digits. Cell 147: 1132-1145.
    • (2011) Cell , vol.147 , pp. 1132-1145
    • Montavon, T.1
  • 32
    • 84904003576 scopus 로고    scopus 로고
    • Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • Nagy, A., Gertsenstein, M., Vintersten, K., Behringer, R. (eds.). (2003). Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (2003)
    • Nagy, A.1    Gertsenstein, M.2    Vintersten, K.3    Behringer, R.4
  • 33
    • 0027436330 scopus 로고
    • FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb
    • Niswander, L., Tickle, C., Vogel, A., Booth, I., and Martin, G. R. 1993. FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75: 579-587.
    • (1993) Cell , vol.75 , pp. 579-587
    • Niswander, L.1    Tickle, C.2    Vogel, A.3    Booth, I.4    Martin, G.R.5
  • 34
    • 0142084743 scopus 로고    scopus 로고
    • Scanning human gene deserts for long-range enhancers
    • Nobrega, M. A., Ovcharenko, I., Afzal, V., and Rubin, E. M. 2003. Scanning human gene deserts for long-range enhancers. Science 302: 413.
    • (2003) Science , vol.302 , pp. 413
    • Nobrega, M.A.1    Ovcharenko, I.2    Afzal, V.3    Rubin, E.M.4
  • 35
    • 0031443874 scopus 로고    scopus 로고
    • Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells
    • O'Gorman, S., Dagenais, N. A., Qian, M., and Marchuk, Y. 1997. Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. Proc. Natl. Acad. Sci. USA 94: 14602-14607.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14602-14607
    • O'Gorman, S.1    Dagenais, N.A.2    Qian, M.3    Marchuk, Y.4
  • 36
    • 73649105501 scopus 로고    scopus 로고
    • Promoting developmental transcription
    • Ohler, U., and Wassarman, D. A. 2010. Promoting developmental transcription. Development 137: 15-26.
    • (2010) Development , vol.137 , pp. 15-26
    • Ohler, U.1    Wassarman, D.A.2
  • 37
    • 33751316959 scopus 로고    scopus 로고
    • In vivo enhancer analysis of human conserved non-coding sequences
    • Pennacchio, L. A., et al. 2006. In vivo enhancer analysis of human conserved non-coding sequences. Nature 444: 499-502.
    • (2006) Nature , vol.444 , pp. 499-502
    • Pennacchio, L.A.1
  • 38
    • 84884507478 scopus 로고    scopus 로고
    • CoCiter: an efficient tool to infer gene function by assessing the significance of literature co-citation
    • Qiao, N., Huang, Y., Naveed, H., Green, C. D., and Han, J. J. 2013. CoCiter: an efficient tool to infer gene function by assessing the significance of literature co-citation. PLoS ONE 8: e74074.
    • (2013) PLoS ONE , vol.8
    • Qiao, N.1    Huang, Y.2    Naveed, H.3    Green, C.D.4    Han, J.J.5
  • 39
    • 84864050183 scopus 로고    scopus 로고
    • Integration of the transcriptional networks regulating limb morphogenesis
    • Rabinowitz, A. H., and Vokes, S. A. 2012. Integration of the transcriptional networks regulating limb morphogenesis. Dev. Biol. 368: 165-180.
    • (2012) Dev. Biol. , vol.368 , pp. 165-180
    • Rabinowitz, A.H.1    Vokes, S.A.2
  • 41
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle, R. D., Johnson, R. L., Laufer, E., and Tabin, C. 1993. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75: 1401-1416.
    • (1993) Cell , vol.75 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4
  • 42
    • 10744220883 scopus 로고    scopus 로고
    • Cited1 is required in trophoblasts for placental development and for embryo growth and survival
    • Rodriguez, T. A., et al. 2004. Cited1 is required in trophoblasts for placental development and for embryo growth and survival. Mol. Cell. Biol. 24: 228-244.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 228-244
    • Rodriguez, T.A.1
  • 43
    • 79953176250 scopus 로고    scopus 로고
    • Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor
    • Ruf, S., et al. 2011. Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat. Genet. 43: 379-386.
    • (2011) Nat. Genet. , vol.43 , pp. 379-386
    • Ruf, S.1
  • 44
    • 36448949026 scopus 로고    scopus 로고
    • Multivalent engagement of chromatin modifications by linked binding modules
    • Ruthenburg, A. J., Li, H., Patel, D. J., and Allis, C. D. 2007. Multivalent engagement of chromatin modifications by linked binding modules. Nat. Rev. Mol. Cell. Biol. 8: 983-994.
    • (2007) Nat. Rev. Mol. Cell. Biol. , vol.8 , pp. 983-994
    • Ruthenburg, A.J.1    Li, H.2    Patel, D.J.3    Allis, C.D.4
  • 45
    • 14844341770 scopus 로고    scopus 로고
    • Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb
    • Sagai, T., Hosoya, M., Mizushina, Y., Tamura, M., and Shiroishi, T. 2005. Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb. Development 132: 797-803.
    • (2005) Development , vol.132 , pp. 797-803
    • Sagai, T.1    Hosoya, M.2    Mizushina, Y.3    Tamura, M.4    Shiroishi, T.5
  • 46
    • 0346040475 scopus 로고    scopus 로고
    • Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog (Shh)
    • Sagai, T., et al. 2004. Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog (Shh). Mamm. Genome 15: 23-34.
    • (2004) Mamm. Genome , vol.15 , pp. 23-34
    • Sagai, T.1
  • 47
    • 33646254416 scopus 로고    scopus 로고
    • Development of bat flight: morphologic and molecular evolution of bat wing digits
    • Sears, K. E., Behringer, R. R., Rasweiler, J. J., and Niswander, L. A. 2006. Development of bat flight: morphologic and molecular evolution of bat wing digits. Proc. Natl. Acad. Sci. USA 103: 6581-6586.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 6581-6586
    • Sears, K.E.1    Behringer, R.R.2    Rasweiler, J.J.3    Niswander, L.A.4
  • 48
    • 0030878664 scopus 로고    scopus 로고
    • Fossils, genes and the evolution of animal limbs
    • Shubin, N., Tabin, C., and Carroll, S. 1997. Fossils, genes and the evolution of animal limbs. Nature 388: 639-648.
    • (1997) Nature , vol.388 , pp. 639-648
    • Shubin, N.1    Tabin, C.2    Carroll, S.3
  • 49
    • 60149092301 scopus 로고    scopus 로고
    • Deep homology and the origins of evolutionary novelty
    • Shubin, N., Tabin, C., and Carroll, S. 2009. Deep homology and the origins of evolutionary novelty. Nature 457: 818-823.
    • (2009) Nature , vol.457 , pp. 818-823
    • Shubin, N.1    Tabin, C.2    Carroll, S.3
  • 50
    • 33645745783 scopus 로고    scopus 로고
    • The pectoral fin of Tiktaalik roseae and the origin of the tetrapod limb
    • Shubin, N. H., Daeschler, E. B., and Jenkins, F. A. Jr., 2006. The pectoral fin of Tiktaalik roseae and the origin of the tetrapod limb. Nature 440: 764-771.
    • (2006) Nature , vol.440 , pp. 764-771
    • Shubin, N.H.1    Daeschler, E.B.2    Jenkins Jr., F.A.3
  • 51
    • 23044477774 scopus 로고    scopus 로고
    • Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes
    • Spitz, F., Herkenne, C., Morris, M. A., and Duboule, D. 2005. Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat. Genet. 37: 889-893.
    • (2005) Nat. Genet. , vol.37 , pp. 889-893
    • Spitz, F.1    Herkenne, C.2    Morris, M.A.3    Duboule, D.4
  • 52
    • 84868587480 scopus 로고    scopus 로고
    • A fast and sensitive alternative for beta-galactosidase detection in mouse embryos
    • Sundararajan, S., Wakamiya, M., Behringer, R. R., and Rivera-Perez, J. A. 2012. A fast and sensitive alternative for beta-galactosidase detection in mouse embryos. Development 139: 4484-4490.
    • (2012) Development , vol.139 , pp. 4484-4490
    • Sundararajan, S.1    Wakamiya, M.2    Behringer, R.R.3    Rivera-Perez, J.A.4
  • 53
    • 79959887501 scopus 로고    scopus 로고
    • Genome-wide identification of conserved regulatory function in diverged sequences
    • Taher, L., et al. 2011. Genome-wide identification of conserved regulatory function in diverged sequences. Genome Res. 21: 1139-1149.
    • (2011) Genome Res. , vol.21 , pp. 1139-1149
    • Taher, L.1
  • 54
    • 29744447562 scopus 로고    scopus 로고
    • Control of Hoxd genes' collinearity during early limb development
    • Tarchini, B., and Duboule, D. 2006. Control of Hoxd genes' collinearity during early limb development. Dev. Cell. 10: 93-103.
    • (2006) Dev. Cell. , vol.10 , pp. 93-103
    • Tarchini, B.1    Duboule, D.2
  • 55
    • 33847277297 scopus 로고    scopus 로고
    • Enhancer identification through comparative genomics
    • Visel, A., Bristow, J., and Pennacchio, L. A. 2007a. Enhancer identification through comparative genomics. Semin. Cell. Dev. Biol. 18: 140-152.
    • (2007) Semin. Cell. Dev. Biol. , vol.18 , pp. 140-152
    • Visel, A.1    Bristow, J.2    Pennacchio, L.A.3
  • 56
    • 70249088327 scopus 로고    scopus 로고
    • Genomic views of distant-acting enhancers
    • Visel, A., Rubin, E. M., and Pennacchio, L. A. 2009a. Genomic views of distant-acting enhancers. Nature 461: 199-205.
    • (2009) Nature , vol.461 , pp. 199-205
    • Visel, A.1    Rubin, E.M.2    Pennacchio, L.A.3
  • 57
  • 58
    • 38649123306 scopus 로고    scopus 로고
    • Ultraconservation identifies a small subset of extremely constrained developmental enhancers
    • Visel, A., et al. 2008. Ultraconservation identifies a small subset of extremely constrained developmental enhancers. Nat. Genet. 40: 158-160.
    • (2008) Nat. Genet. , vol.40 , pp. 158-160
    • Visel, A.1
  • 59
    • 60149091656 scopus 로고    scopus 로고
    • ChIP-seq accurately predicts tissue-specific activity of enhancers
    • Visel, A., et al. 2009b. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457: 854-858.
    • (2009) Nature , vol.457 , pp. 854-858
    • Visel, A.1
  • 60
    • 53549125545 scopus 로고    scopus 로고
    • A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb
    • Vokes, S. A., Ji, H., Wong, W. H., and McMahon, A. P. 2008. A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb. Genes Dev. 22: 2651-2663.
    • (2008) Genes Dev. , vol.22 , pp. 2651-2663
    • Vokes, S.A.1    Ji, H.2    Wong, W.H.3    McMahon, A.P.4
  • 61
    • 77951907509 scopus 로고    scopus 로고
    • The origin of digits: expression patterns versus regulatory mechanisms
    • Woltering, J. M., and Duboule, D. 2010. The origin of digits: expression patterns versus regulatory mechanisms. Dev. Cell. 18: 526-532.
    • (2010) Dev. Cell. , vol.18 , pp. 526-532
    • Woltering, J.M.1    Duboule, D.2
  • 62
    • 69949136621 scopus 로고    scopus 로고
    • Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis
    • Wong, S. Y., et al. 2009. Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat. Med. 15: 1055-1061.
    • (2009) Nat. Med. , vol.15 , pp. 1055-1061
    • Wong, S.Y.1
  • 63
    • 70449805406 scopus 로고    scopus 로고
    • Vertebrate limb bud development: moving towards integrative analysis of organogenesis
    • Zeller, R., Lopez-Rios, J., and Zuniga, A. 2009. Vertebrate limb bud development: moving towards integrative analysis of organogenesis. Nat. Rev. Genet. 10: 845-858.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 845-858
    • Zeller, R.1    Lopez-Rios, J.2    Zuniga, A.3
  • 64
    • 0141816679 scopus 로고    scopus 로고
    • Identification and regulation of tissue-specific cis-acting elements associated with the human AP-2alpha gene
    • Zhang, J., and Williams, T. 2003. Identification and regulation of tissue-specific cis-acting elements associated with the human AP-2alpha gene. Dev. Dyn. 228: 194-207.
    • (2003) Dev. Dyn. , vol.228 , pp. 194-207
    • Zhang, J.1    Williams, T.2
  • 65
    • 3042696502 scopus 로고    scopus 로고
    • Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression
    • Zuniga, A., et al. 2004. Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. Genes Dev. 18: 1553-1564.
    • (2004) Genes Dev. , vol.18 , pp. 1553-1564
    • Zuniga, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.