Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog (Shh)

Mammalian Genome

Volumn 15, Issue 1, 2004, Pages 23-34

  Sagai, Tomoko ^a   Masuya, Hiroshi ^b   Tamura, Masaru ^a   Shimizu, Kunihiko ^c   Yada, Yukari ^a   Wakana, Shigeharu ^b   Gondo, Yoichi ^b   Noda, Tetsuo ^b   Shiroishi, Toshihiko ^a,b  

^a NATIONAL INSTITUTE OF GENETICS   (Japan)

^b RIKEN YOKOHAMA INSTITUTE   (Japan)

^c NIHON UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; SONIC HEDGEHOG PROTEIN;

ALLELE; AMPHIBIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FINGER; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; GENOME ANALYSIS; INTRON; LIMB; LIMB DEVELOPMENT; LMBR1 GENE; MOLECULAR CLONING; MOUSE; MOUSE MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLARIZATION; PROTEIN EXPRESSION; REPTILE; TELEOST;

ANIMALS; BASE SEQUENCE; CONSERVED SEQUENCE; CROSSES, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REGULATOR; GENETIC MARKERS; GENOME; HEDGEHOG PROTEINS; LIMB BUD; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MINOR HISTOCOMPATIBILITY ANTIGENS; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; MUTATION; PHYLOGENY; POLYDACTYLY; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANS-ACTIVATORS;

AMPHIBIA; ANIMALIA; ERINACEIDAE; PISCES; REPTILIA; TELEOSTEI; TETRAPODA; VERTEBRATA;

EID: 0346040475     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-033-2317-5     Document Type: Article

References (45)

1. Bejder L, Hall BK (2002) Limbs in whales and limbless in other vertebrates: mechanisms of evolutionary and developmental transformation and loss. Evol Dev 4, 445-458
2. Blanc I, Bach A, Robert B (2002) Unusual patter of Sonic hedgegog expression in the polydactylous mouse mutant hemimelic extra-toes. Int J Dev Biol 46, 969-974
3. Carroll R (1988) Vertebrate Paleontology and Evolution. (New York: Freeman)
4. Charite J, MacFadden DG, Olson EN (2000) The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development. Development 127, 2461-2470
5. Clack JA (2002) Gaining Ground: The Origin and Evolution of Tetrapods. (Bloomington, Ind: Indiana University Press)
6. Clark RM, Marker PC, Kingsley DM (2000) A novel candidate gene for mouse and human preaxial polydactyly with altered expression in limbs of Hemimelic extra-toes mutant mice. Genomics 67, 19-27
7. Coghill EL, Hugill A, Parkinson N, Davison, D, Glenister P et al. (2002) A gene-driven approach to the identification of ENU mutants in the mouse. Nat Genet 30, 255-256
8. Cohn MJ, Tickle C (1999) Developmental basis of limblessness and axial patterning in snakes. Nature 399, 474-479
9. Drossopoulou F, Lewis KE, Sanz-Ezquerro JJ, Nikbakht N, McMahon AP et al. (2000) A model for anteroposterior patterning of the vertebrate limb based on sequential long-and short-range Shh signaling anf Bmp signaling. Development 127, 1337-1348
10. Echelard Y, Epstein DJ, ST-Jacques B, Shen L, Mohler J et al. (1993) Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430
11. Endo T, Yokoyama H, Tamura K, Ide H (1997) Shh expression in developing and regenerating limb buds of Xenopus laevis. Dev Dyn 209, 227-232
12. Heus HC, Hing A, van Baren MJ, Joose M, Breedveld GJ et al. (1999) A physical and transcriptional map of the preaxial polydactyly locus on chromosome 7q36. Genomics 57, 342-351
13. Heutink P, Zguricas J, Oosterhout Lv, Breedveld GJ, Testers L et al. (1994) The gene for triphalangeal thumb maps to the subtelomellic region of chromosome 7q. Nat Genet 6, 287-292
14. Hui CC, Joyner AL (1993) A mouse model of Greig cephalopolysyndactyly syndrome: the extra-toes J mutation contains an intragenic deletion of the Gli3 gene. Nat Genet 3, 241-245
15. Ianakiev P, van Baren MJ, Daly MJ, Toledo SP, Cavalcanti MG et al. (2001) Acheiropodia is caused by a genomic deletion in C7orf2, the human orthologue of the Lmbr1 gene. Am J Hum Genet 68, 38-45
16. Johnson RL, Tabin CJ (1997) Molecular models for vertebrate limb development. Cell 90, 979-990
17. x). J Embryol Exp Morphol 65 (Suppl), 289-307
18. Koide T, Moriwaki K, Uchida K, Mita A, Sagai T et al. (1998) A new inbred strain JF1 established from Japanese fancy mouse carrying the classic piebald allele. Mamm Genome 9, 15-19
19. Krauss S, Concordet JP, Ingham PW (1993) A functionally conserved homolog of the Drosophila segment polarity gene hedgehog is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75, 1431-1444
20. Lettice LA, Horikoshi T, Heaney SJ, Baren MJ, van der Linde HC, et al. (2002) Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly. Proc Natl Acad Sci USA 99, 7543-7553
21. Lettice LA, Heaney SJ, Purdie LA, Li L, De Beer P, et al. (2003) A long-range Shh enhancer regulates expression in the developing limb and fin is associated with preaxial polydactyly. Hum Mol Genet 12, 1725-1735
22. Litingtung Y, Dahn RD, Li Y, Fallon JF, Chiang C (2002) Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity. Nature 418, 979-983
23. Martin GR, Richman M, Reinsert S, Nadeau JH, Joyner A (1990) Mapping of the two mouse engrailed-like genes: close linkage of En-1 to dominant hemimelia (Dh) on chromosome 1 and of En-2 to hemimelic extra-toes (Hx) on chromosome 5. Genomics 6, 302-308
24. Masuya H, Sagai T, Wakana S, Moriwaki K, Shiroishi T (1995) A duplicated zone of polarizing activity in polydactylous mouse mutants. Genes Dev 9, 1645-1653
25. Masuya H, Sagai T, Moriwaki K, Shiroishi T (1997) Multigenic crontrol of the localization of the zone of polarizing activity in limb morphogenesis in the mouse. Dev Biol 182, 42-51
26. Niswander L, Martin GR (1992) Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768
27. Qu S, Niswander KD, Ji Q, ven der Meer R, Keeney D, Magnuson MA, Wisdom R (1997) Polydactyly and ectopic ZPA formation in Alx-4 mutant mice. Development 124, 3999-4008
28. Riddle RD, Johnson RL, Laufer E, Tabin C (1993) Sonic hedgehog mediates the polarizing activity of ZPA. Cell 75, 1401-1416
29. Sasaki H (1995) cDNA selection by in-solution hybridization. Jikken Igaku 13, 87-93
30. Saunders JW, Gasseling MT (1968) Ectodermal-mesenchymal interactions in the origin of limb symmetry. In: Fleischmajor R, Billingham RE (eds) Epithelial-Mesenxhymal Interactions. (Baltimore: Williams and Wilkins), pp 78-97
31. Sharpe J, Lettice L, Hecksher-Sorensen J, Fox M, Hill R, Krumlauf R (1999) Identification of sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch. Curr Biol 9, 97-100
32. Shimamura M, Yasue H, Ohshima K, Abe H, Kato H, et al. (1997) Molecular evidence from retroposons that whales form a clade within even-toed ungulates. Nature 388, 666-670
33. Sivastava D, Cserjesi P, Olson EN (1995) A subclass of bHLH proteins required for cardiac morphogenesis. Science 270, 1995-1999
34. Tabin CJ (1992) Why we have (only) five fingers per hand: hox genes and the evolution of paired limbs. Development 116, 289-296
35. Tanaka M, Munsterberg A, Anderson, WG, Prescott AR, Hazon N et al. (2002) Fin development in a cartilaginous fish and the origin of vertebrate limbs. Nature 416, 527-531
36. te Welsher P, Fernandez-Teran M, Ros MA, Zeller R (2002a) Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling. Genes Dev 16, 421-426
37. te Welscher P, Zuniga A, Kuijper S, Drenth T, Goedemans HJ, et al. (2002b) Progression of vertebrate limb development through SHH-mediated counteraction of GLI3. Science 298, 827-830
38. Thacher J (1877) Median and paired fins, a contribution to the history of vertebrate limbs. Trans Conn Acad 3, 281-310
39. Torok MA, Gardner DM, Izpisua-Belmonte JC, Bryant SV (1999) Sonic hedgehog (shh) expression in developing and regenerating axolotl limbs. J Exp Zool 284, 197-206
40. Tsukurov O, Boehmer A, Flynn J, Nicolai JP, Hamel BC, et al. (1994) A complex bilateral polysyndactyly disease locus maps to chromosome 7q36. Nat Genet 6, 282-286
41. Wallin J, Wilting J, Koseki H, Fritsch R, Christ B, Balling R (1994) The role of Pax-1 in axial skeleton development. Development 120, 1109-1121
42. Wang B, Fallon JF, Beachy PA (2000) Hedgehog-regulated processing of Gli3 produces an anterior/posterior represser gradient in the developing vertebrate limb. Cell 100, 423-434
43. Wilkinson DG (1992) In Situ Hybridization: A Practical Approach. (Oxford, UK: Oxford University Press)
44. Yang Y, Drossopoulou G, Chuang PT, Duprez D, Marti E, et al. (1997) Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb. Development 124, 4393-4404
45. Zhu M, Yu X (2002) A primitive fish close to the common ancestor of tetrapods and lungfish. Nature 418, 767-770