RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis

Oncogene

Volumn 33, Issue 27, 2014, Pages 3604-3611

  Huang, J ^a   Stewart, A ^a   Maity, B ^a   Hagen, J ^a   Fagan, R L ^a   Yang, J ^a   Quelle, D E ^a   Brenner, C ^a   Fisher, R A ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

apoptosis; cellular transformation; Dnmt1; Ras; RGS protein; Tip60

Indexed keywords

CASPASE 3; DNA METHYLTRANSFERASE 1; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; RAS PROTEIN; RGS PROTEIN; RGS6 PROTEIN; TIP60 PROTEIN; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME DEGRADATION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION;

MUS;

ANIMALS; APOPTOSIS; CELL LINE; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; HISTONE ACETYLTRANSFERASES; HUMANS; MICE; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS P21(RAS); RGS PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 84903880930     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.324     Document Type: Article

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