5-Aza-2′-deoxycytidine-induced genome rearrangements are mediated by DNMT1

Oncogene

Volumn 31, Issue 50, 2012, Pages 5172-5179

  Maslov, A Y ^a   Lee, M ^a   Gundry, M ^a   Gravina, S ^a   Strogonova, N ^a   Tazearslan, C ^a   Bendebury, A ^a   Suh, Y ^a,b   Vijg, J ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

5 aza 20 deoxycytidine; DNA methylation; DNMT1; genome rearrangements; mutations

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ACTIVATION INDUCED CYTIDINE DEAMINASE; DNA METHYLTRANSFERASE 1;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL PROLIFERATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; COVALENT BOND; DEMETHYLATION; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; EXCISION REPAIR; FIBROBLAST; FLOW CYTOMETRY; GENE FREQUENCY; GENE LOCUS; GENE REARRANGEMENT; GENOTOXICITY; INHIBITION KINETICS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SUBSTITUTION REACTION;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; CELL PROLIFERATION; CELLS, CULTURED; CYTIDINE DEAMINASE; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; DOWN-REGULATION; FIBROBLASTS; GENE REARRANGEMENT; HISTONES; MICE; MICE, TRANSGENIC; MUTAGENESIS; MUTATION;

ANIMALIA;

EID: 84871195942     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.9     Document Type: Article

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