The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1

Journal of Biological Chemistry

Volumn 286, Issue 17, 2011, Pages 15344-15351

  Syeda, Farisa ^a   Fagan, Rebecca L ^b   Wean, Matthew ^b   Avvakumov, George V ^a   Walker, John R ^a   Xue, Sheng ^a   Dhe Paganon, Sirano ^a   Brenner, Charles ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ACTIVITIES; BINDING PROTEINS; CATALYTIC DOMAINS; CATALYTIC FUNCTIONS; DINUCLEOTIDES; DNA BINDING; DNA METHYLTRANSFERASES; DNA SUBSTRATES; ENZYMATIC ACTIVITIES; FLUOROGENICS; KINETIC ANALYSIS; MAMMALIAN GENOMES; N-TERMINALS; NAKED DNA; PROTEIN ASSOCIATIONS; REPLICATION FOCI; SUBCELLULAR LOCALIZATIONS;

CRYSTAL STRUCTURE; GENE TRANSFER; MAMMALS; NUCLEIC ACIDS;

DNA;

BINDING PROTEIN; DNA METHYLTRANSFERASE 1; NAKED DNA; REPLICATION FOCUS TARGETING SEQUENCE DOMAIN PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHICKEN; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ERYTHROCYTE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CHICKENS; CRYSTALLOGRAPHY, X-RAY; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA REPLICATION; DNA-BINDING PROTEINS; HUMANS; KINETICS; NUCLEOSOMES; PROTEIN STRUCTURE, TERTIARY;

MAMMALIA;

EID: 79955370122     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.209882     Document Type: Article

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