Reduction of pancreatic cancer cell viability and induction of apoptosis mediated by siRNA targeting DNMT1 through suppression of total DNA methyltransferase activity

Molecular Medicine Reports

Volumn 3, Issue 4, 2010, Pages 699-704

  Xu, Min ^a   Gao, Jun ^a   Du, Yi Qi ^a   Gao, Dao Jian ^a   Zhang, Yu Qi ^a   Li, Zhao Shen ^a   Zhang, You Li ^b   Gong, Yan Fang ^a   Xu, Ping ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF JIANGSU UNIVERSITY   (China)

Author keywords

DNA methylation; DNA methytransferase 1; Pancreatic cancer; Small interfering RNA

Indexed keywords

DNA METHYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MLH1; PROTEIN P21; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DEMETHYLATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE; UPREGULATION;

EID: 77956661140     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr_00000320     Document Type: Article

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