The contribution of the functional IL6R polymorphism rs2228145, eQTLs and other genome-wide SNPs to the heritability of plasma sIL-6R levels

Behavior Genetics

Volumn 44, Issue 4, 2014, Pages 368-382

  Van Dongen, Jenny ^a,b   Jansen, Rick ^b,c   Smit, Dirk ^a,c   Hottenga, Jouke Jan ^a,b   Mbarek, Hamdi ^a,b   Willemsen, Gonneke ^a,b   Kluft, Cornelis ^d   Penninx, Brenda W J ^b,c   Ferreira, Manuel A ^e   Boomsma, Dorret I ^a,b,c   De Geus, Eco J C ^a,b  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Department of Psychiatry VU University Medical Center ^*  (Netherlands)

^d Good Biomarker Sciences   (Netherlands)

^e QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

eQTL; Gene expression; GWAS; Heritability; Inflammation; Soluble interleukin 6 receptor

Indexed keywords

INTERLEUKIN 6 RECEPTOR;

ARTICLE; CHROMOSOME; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC POLYMORPHISM; HERITABILITY; HUMAN; LINKAGE ANALYSIS; MALE; PLASMA; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; TWINS; BLOOD; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; NETHERLANDS;

ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; NETHERLANDS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RECEPTORS, INTERLEUKIN-6;

EID: 84903817603     PISSN: 00018244     EISSN: 15733297     Source Type: Journal    
DOI: 10.1007/s10519-014-9656-8     Document Type: Article

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