메뉴 건너뛰기




Volumn 5, Issue 6, 2004, Pages 513-516

Polymorphisms in the IL-6 receptor (IL-6R) gene: Strong evidence that serum levels of soluble IL-6R are genetically influenced

Author keywords

IL 6 receptor; Japanese; Serum; SNP; Soluble IL 6R

Indexed keywords

ALANINE; ASPARTIC ACID; GLYCINE; INTERLEUKIN 6 RECEPTOR; MESSENGER RNA;

EID: 4644371697     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6364120     Document Type: Article
Times cited : (132)

References (21)
  • 1
    • 0023685762 scopus 로고
    • Cloning and expression of the human Interleukin-6 (BSF-2/IFN-beta) receptor
    • Yamasaki K, Taga T, Hirata Y. Cloning and expression of the human Interleukin-6 (BSF-2/IFN-beta) receptor. Science 1988; 241: 825-828.
    • (1988) Science , vol.241 , pp. 825-828
    • Yamasaki, K.1    Taga, T.2    Hirata, Y.3
  • 2
    • 0025831148 scopus 로고
    • The interleukin-6-dependent DNA-binding protein gene (transcription factor 5: TCF5) maps to human chromosome 20 and rat chromosome 3, the IL-6 receptor locus (IL-6R) to human chromosome 1 and the rat chromosome 2, and the rat IL-6 gene to rat chromosome 4
    • Szpirer J, Szpirer C, Riviere M et al. The interleukin-6-dependent DNA-binding protein gene (transcription factor 5: TCF5) maps to human chromosome 20 and rat chromosome 3, the IL-6 receptor locus (IL-6R) to human chromosome 1 and the rat chromosome 2, and the rat IL-6 gene to rat chromosome 4. Genomics 1991; 10: 539-546.
    • (1991) Genomics , vol.10 , pp. 539-546
    • Szpirer, J.1    Szpirer, C.2    Riviere, M.3
  • 3
    • 0028834169 scopus 로고
    • Cloning and chromosal localization of a pseudogene corresponding to an mRNA for a soluble IL-6R
    • Snyder L, Renauld JC, Szpirer C, Content J. Cloning and chromosal localization of a pseudogene corresponding to an mRNA for a soluble IL-6R. DNA Seq 1995; 5: 311-314.
    • (1995) DNA Seq. , vol.5 , pp. 311-314
    • Snyder, L.1    Renauld, J.C.2    Szpirer, C.3    Content, J.4
  • 4
    • 0027398766 scopus 로고
    • The soluble human interleukin-6 receptor is generated by shedding
    • Müllberg J, Schooltnik H, Stoyan T et al. The soluble human interleukin-6 receptor is generated by shedding. Eur J Immunol 1993; 23: 473-480.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 473-480
    • Müllberg, J.1    Schooltnik, H.2    Stoyan, T.3
  • 5
    • 0031764113 scopus 로고    scopus 로고
    • High-level production of alternatively spliced soluble interleukin-6 receptor in serum of patients with adult T-cell leukaemia/HTLV-I-associated myelopathy
    • Horiuchi S, Ampofo W, Koyanagi Y et al. High-level production of alternatively spliced soluble interleukin-6 receptor in serum of patients with adult T-cell leukaemia/HTLV-I-associated myelopathy. Immunology 1998; 95: 360-369.
    • (1998) Immunology , vol.95 , pp. 360-369
    • Horiuchi, S.1    Ampofo, W.2    Koyanagi, Y.3
  • 6
    • 0026828552 scopus 로고
    • Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor
    • Lust J, Donovan K, Kline M, Greipp P, Kyle R, Maihle N. Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor. Cytokine 1992; 4: 96-100.
    • (1992) Cytokine , vol.4 , pp. 96-100
    • Lust, J.1    Donovan, K.2    Kline, M.3    Greipp, P.4    Kyle, R.5    Maihle, N.6
  • 7
    • 0028270409 scopus 로고
    • The soluble human IL-6 receptor - Mutational characterization of the proteolytic cleavage site
    • Müllberg J, Oberthür W, Lottspeich F et al. The soluble human IL-6 receptor - mutational characterization of the proteolytic cleavage site. J Immunol 1994; 15: 4958-4968.
    • (1994) J. Immunol. , vol.15 , pp. 4958-4968
    • Müllberg, J.1    Oberthür, W.2    Lottspeich, F.3
  • 8
    • 0029795014 scopus 로고    scopus 로고
    • Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide
    • Walev I, Vollmer P, Palmer M, Bhakdi S, Rose-John S. Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide. Proc Natl Acad Sci USA 1996; 93: 7882-7887.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7882-7887
    • Walev, I.1    Vollmer, P.2    Palmer, M.3    Bhakdi, S.4    Rose-John, S.5
  • 9
    • 0031471861 scopus 로고    scopus 로고
    • Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 alpha
    • Modur V, Li Y, Zimmerman GA, Prescott SM, McIntyre TM. Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 alpha. J Clin Invest 1997; 100: 2752-2756.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2752-2756
    • Modur, V.1    Li, Y.2    Zimmerman, G.A.3    Prescott, S.M.4    McIntyre, T.M.5
  • 10
    • 18244419398 scopus 로고    scopus 로고
    • Extramedullary expansion of hematopoietic progenitor cells in IL-6/sIL-6R double transgenic mice
    • Peters M, Schirmacher P, Goldschmitt J et al. Extramedullary expansion of hematopoietic progenitor cells in IL-6/sIL-6R double transgenic mice. J Exp Med 1997; 185: 755-766.
    • (1997) J. Exp. Med. , vol.185 , pp. 755-766
    • Peters, M.1    Schirmacher, P.2    Goldschmitt, J.3
  • 11
    • 0030891228 scopus 로고    scopus 로고
    • Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment
    • Romano M, Sironi M, Toniatti C et al. Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity 1997; 6: 315-325.
    • (1997) Immunity , vol.6 , pp. 315-325
    • Romano, M.1    Sironi, M.2    Toniatti, C.3
  • 12
    • 10244227926 scopus 로고    scopus 로고
    • Analysis of interleukin-6 receptor and gp130 expressions and proliferative capability of human CD34+ cells
    • Tajima S, Tsuji K, Ebihara Y et al. Analysis of interleukin-6 receptor and gp130 expressions and proliferative capability of human CD34+ cells. J Exp Med 1996; 184: 1357-1364.
    • (1996) J. Exp. Med. , vol.184 , pp. 1357-1364
    • Tajima, S.1    Tsuji, K.2    Ebihara, Y.3
  • 13
    • 0031446516 scopus 로고    scopus 로고
    • Major role of the interleukin-6/interleukin-6 receptor complex for the proliferation of interleukin-6-dependent human myeloma cell lines
    • Gaillard JP, Liautard J, Klein B, Brochier J. Major role of the interleukin-6/interleukin-6 receptor complex for the proliferation of interleukin-6-dependent human myeloma cell lines. Eur J Immunol 1997; 27: 3332-3340.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3332-3340
    • Gaillard, J.P.1    Liautard, J.2    Klein, B.3    Brochier, J.4
  • 14
    • 0028796711 scopus 로고
    • Soluble interleukin-6 receptors in inflammatory bowel disease: Relation to circulating interleukin-6
    • Mitsuyama K, Toyonaga A, Sasaki E et al. Soluble interleukin-6 receptors in inflammatory bowel disease: relation to circulating interleukin-6. Gut 1995; 36: 45-49.
    • (1995) Gut , vol.36 , pp. 45-49
    • Mitsuyama, K.1    Toyonaga, A.2    Sasaki, E.3
  • 15
    • 0028883640 scopus 로고
    • Detection of membrane and soluble interleukin-6 receptor in lymphoid malignancies
    • Lavabre-Bertrand T, Exbrayar C, Lautard J et al. Detection of membrane and soluble interleukin-6 receptor in lymphoid malignancies. Br J Haematol 1995; 91: 871-877.
    • (1995) Br. J. Haematol. , vol.91 , pp. 871-877
    • Lavabre-Bertrand, T.1    Exbrayar, C.2    Lautard, J.3
  • 16
    • 0023942493 scopus 로고
    • Interleukin-6 in synovial fluid and serum in patients with rheumatoid arthritis and other inflammatory arthritis
    • Hossaim F, Devogelaer J, van Damme J, Deuxchaines C, van Snick J. Interleukin-6 in synovial fluid and serum in patients with rheumatoid arthritis and other inflammatory arthritis. Art Rheum 1988; 31: 784-788.
    • (1988) Art. Rheum. , vol.31 , pp. 784-788
    • Hossaim, F.1    Devogelaer, J.2    van Damme, J.3    Deuxchaines, C.4    van Snick, J.5
  • 18
    • 0037387714 scopus 로고    scopus 로고
    • Identification of novel SNPs in the Interleukin 6 Receptor Gene
    • Kim HL, Lee HS, Kim YJ et al. Identification of novel SNPs in the Interleukin 6 Receptor Gene. Hum Mutat 2003; 21: 450-451.
    • (2003) Hum. Mutat. , vol.21 , pp. 450-451
    • Kim, H.L.1    Lee, H.S.2    Kim, Y.J.3
  • 19
    • 0030028959 scopus 로고    scopus 로고
    • Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
    • Chua S, Chung N, Wu-Peng S et al. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 1996; 271: 994-996.
    • (1996) Science , vol.271 , pp. 994-996
    • Chua, S.1    Chung, N.2    Wu-Peng, S.3
  • 20
    • 0033861080 scopus 로고    scopus 로고
    • Soluble leptin receptor in serum of subjects with complete resistance to leptin. Relation to fat mass
    • Lahlou N, Clement K, Carel JC et al. Soluble leptin receptor in serum of subjects with complete resistance to leptin. Relation to fat mass. Diabetes 2000; 49: 1347-1352.
    • (2000) Diabetes , vol.49 , pp. 1347-1352
    • Lahlou, N.1    Clement, K.2    Carel, J.C.3
  • 21
    • 0034673970 scopus 로고    scopus 로고
    • Roles of the NFI/CTF gene family in transcription and development
    • Gronostajski R. Roles of the NFI/CTF gene family in transcription and development. Gene 2000; 249: 31-45.
    • (2000) Gene , vol.249 , pp. 31-45
    • Gronostajski, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.