A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects

Genes and Immunity

Volumn 8, Issue 7, 2007, Pages 552-559

  Rafiq, S ^a   Frayling, T M ^a   Murray, A ^a   Hurst, A ^a   Stevens, K ^a   Weedon, M N ^a   Henley, W ^b   Ferrucci, L ^c   Bandinelli, S ^d   Corsi, A M ^e   Guralnik, J M ^f   Melzer, D ^a  

^a PENINSULA MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY OF PLYMOUTH   (United Kingdom)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d CNR   (Italy)

^e UNIVERSITY OF FLORENCE   (Italy)

^f NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALANINE; ALPHA 2 MACROGLOBULIN; ASPARTIC ACID; GAMMA INTERFERON; GLUCOSE; GLYCOPROTEIN GP 130; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ALLELE; ARTICLE; ASTHMA; CARDIOVASCULAR DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; COXITIS; CYTOKINE PRODUCTION; DIABETES MELLITUS; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HAPLOTYPE MAP; HOMOZYGOSITY; HUMAN; INFLAMMATION; ITALY; KNEE ARTHRITIS; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REGRESSION ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; WAIST HIP RATIO;

AGED; ALLELES; CYTOKINE RECEPTOR GP130; CYTOKINES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFLAMMATION; INTERLEUKIN-6; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, INTERLEUKIN-6;

EID: 35548974357     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/sj.gene.6364414     Document Type: Article

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