메뉴 건너뛰기




Volumn 38, Issue 1, 2006, Pages 63-71

Shear stress stimulates phosphorylation of protein kinase A substrate proteins including endothelial nitric oxide synthase in endothelial cells

Author keywords

Cyclic AMP responsive element binding protein; Endothelial cells; Nitric oxide synthase type III; Protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOPROTEIN; PROTEIN P135; PROTEIN P50; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 33644793037     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2006.8     Document Type: Article
Times cited : (9)

References (41)
  • 3
    • 0042388672 scopus 로고    scopus 로고
    • Flow-dependent regulation of endothelial nitric oxide synthase: Role of protein kinases
    • Boo YC, Jo H. Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases. Am J Physiol Cell Physiol 2003;285:C499-508
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Boo, Y.C.1    Jo, H.2
  • 4
    • 0036479305 scopus 로고    scopus 로고
    • Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: Role of protein kinase A
    • Boo YC, Sorescu G, Boyd N, Shiojima I, Walsh K, Du J, Jo H. Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A. J Biol Chem 2002b;277:3388-96
    • (2002) J Biol Chem , vol.277 , pp. 3388-3396
    • Boo, Y.C.1    Sorescu, G.2    Boyd, N.3    Shiojima, I.4    Walsh, K.5    Du, J.6    Jo, H.7
  • 6
    • 0030769381 scopus 로고    scopus 로고
    • PKA isoforms, neural pathways, and behaviour: Making the connection
    • Brandon EP, Idzerda RL, McKnight GS. PKA isoforms, neural pathways, and behaviour: making the connection. Curr Opin Neurobiol 1997;7:397-403
    • (1997) Curr Opin Neurobiol , vol.7 , pp. 397-403
    • Brandon, E.P.1    Idzerda, R.L.2    McKnight, G.S.3
  • 7
    • 0034681455 scopus 로고    scopus 로고
    • Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-ependent protein kinases
    • Butt E, Bernhardt M, Smolenski A, Kotsonis P, Frohlich LG, Sickmann A, Meyer HE, Lohmann SM, Schmidt HH. Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-ependent protein kinases. J Biol Chem 2000;275:5179-87
    • (2000) J Biol Chem , vol.275 , pp. 5179-5187
    • Butt, E.1    Bernhardt, M.2    Smolenski, A.3    Kotsonis, P.4    Frohlich, L.G.5    Sickmann, A.6    Meyer, H.E.7    Lohmann, S.M.8    Schmidt, H.H.9
  • 8
    • 0034724923 scopus 로고    scopus 로고
    • Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer
    • Chen PF, Wu KK. Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer. J Biol Chem 2000;275:13155-63
    • (2000) J Biol Chem , vol.275 , pp. 13155-13163
    • Chen, P.F.1    Wu, K.K.2
  • 9
    • 0032544011 scopus 로고    scopus 로고
    • Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase
    • USA
    • Cheng X, Ma Y, Moore M, Hemmings BA, Taylor SS. Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proc Natl Acad Sci USA 1998;95:9849-54
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 9849-9854
    • Cheng, X.1    Ma, Y.2    Moore, M.3    Hemmings, B.A.4    Taylor, S.S.5
  • 10
    • 12344306644 scopus 로고    scopus 로고
    • The role of shear stress in the pathogenesis of atherosclerosis
    • Cunningham KS, Gotlieb AI. The role of shear stress in the pathogenesis of atherosclerosis. Lab Invest 2005;85:942
    • (2005) Lab Invest , vol.85 , pp. 942
    • Cunningham, K.S.1    Gotlieb, A.I.2
  • 12
    • 0036846410 scopus 로고    scopus 로고
    • Multiple signaling pathways in flow-mediated endothelial mechanotransduction: PYK-ing the right location
    • Davies PF. Multiple signaling pathways in flow-mediated endothelial mechanotransduction: PYK-ing the right location. Arterioscler Thromb Vasc Biol 2002;22:1755-7
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1755-1757
    • Davies, P.F.1
  • 13
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 1999;399:601-5
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 14
    • 0035877750 scopus 로고    scopus 로고
    • Cyclic AMP-independent activation of protein kinase A by vasoactive peptides
    • Dulin NO, Niu J, Browning DD, Ye RD, Voyno-Yasenetskaya T. Cyclic AMP-independent activation of protein kinase A by vasoactive peptides. J Biol Chem 2001;276:20827-30
    • (2001) J Biol Chem , vol.276 , pp. 20827-20830
    • Dulin, N.O.1    Niu, J.2    Browning, D.D.3    Ye, R.D.4    Voyno-Yasenetskaya, T.5
  • 16
    • 27144465277 scopus 로고    scopus 로고
    • Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells
    • Fleming I, Fisslthaler B, Dixit M, Busse R. Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells. J Cell Sci 2005;118:4103-11
    • (2005) J Cell Sci , vol.118 , pp. 4103-4111
    • Fleming, I.1    Fisslthaler, B.2    Dixit, M.3    Busse, R.4
  • 17
    • 0033522927 scopus 로고    scopus 로고
    • Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
    • Fujio Y, Walsh K. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J Biol Chem 1999;274:16349-54
    • (1999) J Biol Chem , vol.274 , pp. 16349-16354
    • Fujio, Y.1    Walsh, K.2
  • 18
    • 3142705856 scopus 로고    scopus 로고
    • Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release
    • Fulton D, Babbitt R, Zoellner S, Fontana J, Acevedo L, McCabe TJ, Iwakiri Y, Sessa WC. Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release. J Biol Chem 2004;279:30349-57
    • (2004) J Biol Chem , vol.279 , pp. 30349-30357
    • Fulton, D.1    Babbitt, R.2    Zoellner, S.3    Fontana, J.4    Acevedo, L.5    McCabe, T.J.6    Iwakiri, Y.7    Sessa, W.C.8
  • 20
    • 0037131346 scopus 로고    scopus 로고
    • Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase
    • Gonzalez E, Kou R, Lin AJ, Golan DE, Michel T. Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase. J Biol Chem 2002;277:39554-60
    • (2002) J Biol Chem , vol.277 , pp. 39554-39560
    • Gonzalez, E.1    Kou, R.2    Lin, A.J.3    Golan, D.E.4    Michel, T.5
  • 21
    • 0037081823 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase activity is linked to its presence at cell-cell contacts
    • Govers R, Bevers L, de Bree P, Rabelink TJ. Endothelial nitric oxide synthase activity is linked to its presence at cell-cell contacts. Biochem J 2002;361:193-201
    • (2002) Biochem J , vol.361 , pp. 193-201
    • Govers, R.1    Bevers, L.2    De Bree, P.3    Rabelink, T.J.4
  • 22
    • 5444231175 scopus 로고    scopus 로고
    • Colocalization of eNOS and the catalytic subunit of PKA in endothelial cell junctions: A clue for regulated NO production
    • Heijnen HF, Waaijenborg S, Crapo JD, Bowler RP, Akkerman JW, Slot JW. Colocalization of eNOS and the catalytic subunit of PKA in endothelial cell junctions: a clue for regulated NO production. J Histochem Cytochem 2004;52:1277-85
    • (2004) J Histochem Cytochem , vol.52 , pp. 1277-1285
    • Heijnen, H.F.1    Waaijenborg, S.2    Crapo, J.D.3    Bowler, R.P.4    Akkerman, J.W.5    Slot, J.W.6
  • 23
    • 0042266790 scopus 로고    scopus 로고
    • Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression
    • Illi B, Nanni S, Scopece A, Farsetti A, Biglioli P, Capogrossi MC, Gaetano C. Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression. Circ Res 2003;93:155-61
    • (2003) Circ Res , vol.93 , pp. 155-161
    • Illi, B.1    Nanni, S.2    Scopece, A.3    Farsetti, A.4    Biglioli, P.5    Capogrossi, M.C.6    Gaetano, C.7
  • 24
    • 0028361984 scopus 로고
    • Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase
    • Liu J, Sessa WC. Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase. J Biol Chem 1994;269:11691-4
    • (1994) J Biol Chem , vol.269 , pp. 11691-11694
    • Liu, J.1    Sessa, W.C.2
  • 25
    • 0027163936 scopus 로고
    • Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP
    • USA
    • Malek AM, Greene AL, Izumo S. Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP. Proc Natl Acad Sci USA 1993;90:5999-6003
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 5999-6003
    • Malek, A.M.1    Greene, A.L.2    Izumo, S.3
  • 26
  • 27
    • 9344231936 scopus 로고    scopus 로고
    • Protein kinase A mediates microglial activation induced by plasminogen and gangliosides
    • Min KJ, Yang MS, Jou I, Joe EH. Protein kinase A mediates microglial activation induced by plasminogen and gangliosides. Exp Mol Med 2004;36:461-7
    • (2004) Exp Mol Med , vol.36 , pp. 461-467
    • Min, K.J.1    Yang, M.S.2    Jou, I.3    Joe, E.H.4
  • 29
    • 0008632745 scopus 로고    scopus 로고
    • Autoinhibition of endothelial nitric-oxide synthase. Identification of an electron transfer control element
    • Nishida CR, Ortiz de Montellano PR. Autoinhibition of endothelial nitric-oxide synthase. Identification of an electron transfer control element. J Biol Chem 1999;274:14692-8
    • (1999) J Biol Chem , vol.274 , pp. 14692-14698
    • Nishida, C.R.1    Ortiz De Montellano, P.R.2
  • 30
    • 0035975936 scopus 로고    scopus 로고
    • Interaction of heterotrimeric G13 protein with an A-kinase-anchoring protein 110 (AKAP110) mediates cAMP-independent PKA activation
    • Niu J, Vaiskunaite R, Suzuki N, Kozasa T, Carr DW, Dulin N, Voyno-Yasenetskaya TA. Interaction of heterotrimeric G13 protein with an A-kinase-anchoring protein 110 (AKAP110) mediates cAMP-independent PKA activation. Curr Biol 2001;11:1686-90
    • (2001) Curr Biol , vol.11 , pp. 1686-1690
    • Niu, J.1    Vaiskunaite, R.2    Suzuki, N.3    Kozasa, T.4    Carr, D.W.5    Dulin, N.6    Voyno-Yasenetskaya, T.A.7
  • 31
    • 0026590175 scopus 로고
    • Mutations in the catalytic subunit of cAMP-dependent protein kinase result in unregulated biological activity
    • USA
    • Orellana SA, McKnight GS. Mutations in the catalytic subunit of cAMP-dependent protein kinase result in unregulated biological activity. Proc Natl Acad Sci USA 1992;89:4726-30
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 4726-4730
    • Orellana, S.A.1    McKnight, G.S.2
  • 32
  • 33
    • 0033543699 scopus 로고    scopus 로고
    • Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A
    • Razani B, Rubin CS, Lisanti MP. Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A. J Biol Chem 1999;274:26353-60
    • (1999) J Biol Chem , vol.274 , pp. 26353-26360
    • Razani, B.1    Rubin, C.S.2    Lisanti, M.P.3
  • 34
    • 0025359865 scopus 로고
    • Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production
    • Reich KM, Gay CV, Frangos JA. Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production. J Cell Physiol 1990;143:100-4
    • (1990) J Cell Physiol , vol.143 , pp. 100-104
    • Reich, K.M.1    Gay, C.V.2    Frangos, J.A.3
  • 37
    • 0027394599 scopus 로고
    • Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytosolic protein
    • Sessa WC, Barber CM, Lynch KR. Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytosolic protein. Circ Res 1993;72:921-4
    • (1993) Circ Res , vol.72 , pp. 921-924
    • Sessa, W.C.1    Barber, C.M.2    Lynch, K.R.3
  • 38
    • 0025807509 scopus 로고
    • CREB: A Ca (2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases
    • Sheng M, Thompson MA, Greenberg ME. CREB: a Ca (2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 1991;252:1427-30
    • (1991) Science , vol.252 , pp. 1427-1430
    • Sheng, M.1    Thompson, M.A.2    Greenberg, M.E.3
  • 39
    • 0031833126 scopus 로고    scopus 로고
    • Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force
    • Traub O, Berk BC. Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol 1998;18:677-85
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 677-685
    • Traub, O.1    Berk, B.C.2
  • 40
    • 0037269575 scopus 로고    scopus 로고
    • Changes of vasodilator-stimulated phosphoprotein (VASP) and its phosphorylation in endothelial cells exposed to laminar flow
    • Wei L, Muller S, Ouyang J, Stoltz JF, Wang X. Changes of vasodilator-stimulated phosphoprotein (VASP) and its phosphorylation in endothelial cells exposed to laminar flow. Clin Hemorheol Microcirc 2003;28:113-20
    • (2003) Clin Hemorheol Microcirc , vol.28 , pp. 113-120
    • Wei, L.1    Muller, S.2    Ouyang, J.3    Stoltz, J.F.4    Wang, X.5
  • 41
    • 0035025773 scopus 로고    scopus 로고
    • cAMP signal transduction cascade, a novel pathway for the regulation of endothelial nitric oxide production in coronary blood vessels
    • Zhang X, Hintze TH. cAMP signal transduction cascade, a novel pathway for the regulation of endothelial nitric oxide production in coronary blood vessels. Arterioscler Thromb Vasc Biol 2001;21:797-803
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 797-803
    • Zhang, X.1    Hintze, T.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.