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Volumn 9, Issue 6, 2014, Pages 895-912

The effects of carbon nanotubes on lung and dermal cellular behaviors

Author keywords

angiogenesis; carbon nanotubes; carcinogenicity; cellular behavior; cytotoxicity; dermal exposure; genotoxicity; inflammation; lung fibrosis; pulmonary exposure

Indexed keywords

CARBON NANOTUBE; MULTI WALLED NANOTUBE; SINGLE WALLED NANOTUBE; CARCINOGEN; MUTAGENIC AGENT;

EID: 84903775463     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.14.42     Document Type: Review
Times cited : (59)

References (101)
  • 1
    • 59849113938 scopus 로고    scopus 로고
    • Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of janus?
    • Shvedova AA, Kisin ER, Porter D et al. Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: two faces of janus? Pharmacol. Ther. 121(2), 192-204 (2009).
    • (2009) Pharmacol Ther , vol.121 , Issue.2 , pp. 192-204
    • Shvedova, A.A.1    Kisin, E.R.2    Porter, D.3
  • 2
    • 34848828552 scopus 로고    scopus 로고
    • Reviewing the environmental and human health knowledge base of carbon nanotubes
    • DOI 10.1289/ehp.9652
    • Helland A, Wick P, Koehler A, Schmid K, Som, C. Reviewing the environmental and human health knowledge base of carbon nanotubes. Environ. Health Perspect. 115(8), 1125-1131 (2007). (Pubitemid 351816702)
    • (2007) Environmental Health Perspectives , vol.115 , Issue.8 , pp. 1125-1131
    • Helland, A.1    Wick, P.2    Koehler, A.3    Schmid, K.4    Som, C.5
  • 3
    • 36549077052 scopus 로고    scopus 로고
    • Carbon nanotubes by the metric ton: Anticipating new commercial applications, producers increase capacity
    • Thayer AM. Carbon nanotubes by the metric ton: anticipating new commercial applications, producers increase capacity. Chem. Eng. News 85(46), 29-35 (2007).
    • (2007) Chem. Eng. News , vol.85 , Issue.46 , pp. 29-35
    • Thayer, A.M.1
  • 5
    • 84873808704 scopus 로고    scopus 로고
    • Carbon nanotubes: Present and future commercial applications
    • De Volder MFL, Tawfick SH, Baughman RH, Hart AJ. Carbon nanotubes: present and future commercial applications. Science 339(6119), 535-539 (2013).
    • (2013) Science , vol.339 , Issue.6119 , pp. 535-539
    • De Volder Mfl1    Tawfick, S.H.2    Baughman, R.H.3    Hart, A.J.4
  • 7
    • 33745597580 scopus 로고    scopus 로고
    • Carbon nanotubes: A review of their properties in relation to pulmonary toxicology and workplace safety
    • DOI 10.1093/toxsci/kfj130
    • Donaldson K, Aitken R, Tran L, Stone V, Duffin R, Forrest G, Alexander A. Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol. Sci. 92(1), 5-22 (2006). (Pubitemid 43985785)
    • (2006) Toxicological Sciences , vol.92 , Issue.1 , pp. 5-22
    • Donaldson, K.1    Aitken, R.2    Tran, L.3    Stone, V.4    Duffin, R.5    Forrest, G.6    Alexander, A.7
  • 8
    • 77957131539 scopus 로고    scopus 로고
    • Review of carbon nanotubes toxicity and exposure - Appraisal of human health risk assessment based on open literature
    • Aschberger K, Johnston HJ, Stone V et al. Review of carbon nanotubes toxicity and exposure - appraisal of human health risk assessment based on open literature. Crit. Rev. Toxicol. 40(9), 759-790 (2010).
    • (2010) Crit. Rev. Toxicol , vol.40 , Issue.9 , pp. 759-790
    • Aschberger, K.1    Johnston, H.J.2    Stone, V.3
  • 10
    • 0043026989 scopus 로고    scopus 로고
    • Surface modification of multiwalled carbon nanotubes: Toward the tailoring of the interface in polymer composites
    • Eitan A, Jiang K, Dukes D, Andrews R, Schadler LS. Surface modification of multiwalled carbon nanotubes: toward the tailoring of the interface in polymer composites. Chem. Mater. 15(16), 3198-3201 (2013).
    • (2013) Chem. Mater , vol.15 , Issue.16 , pp. 3198-3201
    • Eitan, A.1    Jiang, K.2    Dukes, D.3    Andrews, R.4    Schadler, L.S.5
  • 11
    • 77952829224 scopus 로고    scopus 로고
    • A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics
    • Johnston HJ, Hutchison GR, Christensen FM et al. A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: the contribution of physico-chemical characteristics. Nanotoxicology 4(2), 207-246 (2010).
    • (2010) Nanotoxicology , vol.4 , Issue.2 , pp. 207-246
    • Johnston, H.J.1    Hutchison, G.R.2    Christensen, F.M.3
  • 12
    • 84879583118 scopus 로고    scopus 로고
    • Pulmonary toxicity and fibrogenic response of carbon nanotubes
    • Manke A, Wang L, Rojanasakul Y. Pulmonary toxicity and fibrogenic response of carbon nanotubes. Toxicol. Mech. Methods 23(3), 196-206 (2013).
    • (2013) Toxicol. Mech. Methods , vol.23 , Issue.3 , pp. 196-206
    • Manke, A.1    Wang, L.2    Rojanasakul, Y.3
  • 13
    • 84875305657 scopus 로고    scopus 로고
    • Understanding the toxicity of carbon nanotubes
    • Liu Y, Zhao Y, Sun B, Chen C. Understanding the toxicity of carbon nanotubes. Acc. Chem. Res. 46(3), 702-713 (2013).
    • (2013) Acc. Chem. Res , vol.46 , Issue.3 , pp. 702-713
    • Liu, Y.1    Zhao, Y.2    Sun, B.3    Chen, C.4
  • 14
    • 83755178438 scopus 로고    scopus 로고
    • Diameter and rigidity of multi-walled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis
    • Nagai H, Okazaki Y, Chew S et al. Diameter and rigidity of multi-walled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis. Proc. Natl Acad. Sci. USA. 108(49), E1330-E1338 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.49
    • Nagai, H.1    Okazaki, Y.2    Chew, S.3
  • 15
    • 77956186492 scopus 로고    scopus 로고
    • Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape
    • Yamashita K, Yoshioka Y, Higashisaka K et al. Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape. Inflammation 33(4), 276-280 (2010).
    • (2010) Inflammation , vol.33 , Issue.4 , pp. 276-280
    • Yamashita, K.1    Yoshioka, Y.2    Higashisaka, K.3
  • 16
    • 84864006786 scopus 로고    scopus 로고
    • Different cellular response mechanisms contribute to the length-dependent cytotoxicity of multi-walled carbon nanotubes
    • Liu D, Wang L, Wang Z, Cuschieri A. Different cellular response mechanisms contribute to the length-dependent cytotoxicity of multi-walled carbon nanotubes. Nanoscale Res. Lett. 7(1), 361 (2012).
    • (2012) Nanoscale Res. Lett , vol.7 , Issue.1 , pp. 361
    • Liu, D.1    Wang, L.2    Wang, Z.3    Cuschieri, A.4
  • 17
    • 84859195390 scopus 로고    scopus 로고
    • The mechanism of pleural inflammation by long carbon nanotubes: Interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells
    • Murphy FA, Schinwald A, Poland CA, Donaldson K. The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells. Part. Fibre Toxicol. 9, 8 (2012).
    • (2012) Part. Fibre Toxicol , vol.9 , Issue.8
    • Murphy, F.A.1    Schinwald, A.2    Poland, C.A.3    Donaldson, K.4
  • 18
    • 80053320089 scopus 로고    scopus 로고
    • Long, needle-like carbon nanotubes and asbestos activate the NRLP3 inflammasome through a similar mechanism
    • Palomaki J, Valimaki E, Sund J et al. Long, needle-like carbon nanotubes and asbestos activate the NRLP3 inflammasome through a similar mechanism. ACS Nano 5(9), 6861-6870 (2011).
    • (2011) ACS Nano , vol.5 , Issue.9 , pp. 6861-6870
    • Palomaki, J.1    Valimaki, E.2    Sund, J.3
  • 19
    • 80055109585 scopus 로고    scopus 로고
    • The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways
    • Li Y, Liu Y, Fu Y et al. The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways. Biomaterials 33(2), 402-411 (2012).
    • (2012) Biomaterials , vol.33 , Issue.2 , pp. 402-411
    • Li, Y.1    Liu, Y.2    Fu, Y.3
  • 20
    • 77349083887 scopus 로고    scopus 로고
    • Vitro evaluation of cytotoxicity of engineered carbon nanotubes in selected human cell lines
    • Hu X, Cook S, Wang P, Hwang HM, Liu X, Williams QL. In vitro evaluation of cytotoxicity of engineered carbon nanotubes in selected human cell lines. Sci. Totol Environ. 408(8), 1812-1817 (2010).
    • (2010) Sci. Totol Environ , vol.408 , Issue.8 , pp. 1812-1817
    • Hu, X.1    Cook, S.2    Wang, P.3    Hwang, H.M.4    Liu, X.5    Williams, Q.L.6
  • 22
    • 84875658915 scopus 로고    scopus 로고
    • Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity
    • Li R, Wang X, Ji Z et al. Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity. ACS Nano 7(3), 2352-2368 (2013).
    • (2013) ACS Nano , vol.7 , Issue.3 , pp. 2352-2368
    • Li, R.1    Wang, X.2    Ji, Z.3
  • 23
    • 84887826693 scopus 로고    scopus 로고
    • Effect of multi-walled carbon nanotube surface modification on bioactivity in the C57BL/6 mouse model
    • Sager TM, Wolfarth MW, Andrew M et al. Effect of multi-walled carbon nanotube surface modification on bioactivity in the C57BL/6 mouse model. Nanotoxicology 8(3), 317-327 (2014).
    • (2014) Nanotoxicology , vol.8 , Issue.3 , pp. 317-327
    • Sager, T.M.1    Wolfarth, M.W.2    Andrew, M.3
  • 24
    • 84863647683 scopus 로고    scopus 로고
    • Effects of long and short carboxylated or aminated multiwalled carbon nanotubes on blood coagulation
    • Meng J, Cheng X, Liu J et al. Effects of long and short carboxylated or aminated multiwalled carbon nanotubes on blood coagulation. PLoS ONE 7(7), e38995 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.7
    • Meng, J.1    Cheng, X.2    Liu, J.3
  • 25
    • 33845410139 scopus 로고    scopus 로고
    • Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants
    • DOI 10.1016/j.toxlet.2006.11.001, PII S0378427406013178
    • Pulskamp K, Diabate S, Krug HF. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol. Lett. 168(2), 58-74 (2007). (Pubitemid 44909723)
    • (2007) Toxicology Letters , vol.168 , Issue.1 , pp. 58-74
    • Pulskamp, K.1    Diabate, S.2    Krug, H.F.3
  • 27
    • 33947355750 scopus 로고    scopus 로고
    • In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells
    • DOI 10.1016/j.tiv.2006.10.007, PII S0887233306002323
    • Davoren M, Herzog E, Casey A et al. In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells. Toxicol. In Vitro 21(3), 438-448 (2007). (Pubitemid 46453117)
    • (2007) Toxicology in Vitro , vol.21 , Issue.3 , pp. 438-448
    • Davoren, M.1    Herzog, E.2    Casey, A.3    Cottineau, B.4    Chambers, G.5    Byrne, H.J.6    Lyng, F.M.7
  • 29
    • 77149155975 scopus 로고    scopus 로고
    • Direct fibrogenic effects of dispersed single-walled carbon nanotubes on human lung fibroblasts
    • Wang L, Mercer RR, Rojanasakul Y et al. Direct fibrogenic effects of dispersed single-walled carbon nanotubes on human lung fibroblasts. J. Toxicol. Environ. Health A 73(5-6), 410-422 (2010).
    • (2010) J. Toxicol. Environ. Health A , vol.73 , Issue.5-6 , pp. 410-422
    • Wang, L.1    Mercer, R.R.2    Rojanasakul, Y.3
  • 30
    • 25844464705 scopus 로고    scopus 로고
    • Single-walled carbon nanotube induces oxidative stress and activates nuclear transcription factor-κB in human keratinocytes
    • DOI 10.1021/nl0507966
    • Manna SK, Sarkar S, Barr J et al. Single-walled carbon nanotube induces oxidative stress and activates nuclear transcription factor-kappaB in human keratinocytes. Nano Lett. 5(9), 1676-1684 (2005). (Pubitemid 41396145)
    • (2005) Nano Letters , vol.5 , Issue.9 , pp. 1676-1684
    • Manna, S.K.1    Sarkar, S.2    Barr, J.3    Wise, K.4    Barrera, E.V.5    Jejelowo, O.6    Rice-Ficht, A.C.7    Ramesh, G.T.8
  • 31
    • 84881314140 scopus 로고    scopus 로고
    • Carbon nanotube dosimetry: From workplace exposure assessment to inhalation toxicology
    • Dahm M, Chen BT, Birch ME et al. Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology. Toxicologist 132, 99 (2013).
    • (2013) Toxicologist , vol.132 , Issue.99
    • Dahm, M.1    Chen, B.T.2    Birch, M.E.3
  • 33
    • 85057253428 scopus 로고    scopus 로고
    • Occupational exposure to carbon nanotubes and nanofibers
    • NIOSH
    • NIOSH. Occupational exposure to carbon nanotubes and nanofibers. Current Intelligence Bulletin 2013-145 (2013). www.cdc.gov/niosh/docs/2013-145/pdfs/ 2013-145.pdf
    • (2013) Current Intelligence Bulletin 2013-145
  • 34
    • 1542726626 scopus 로고    scopus 로고
    • Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intractracheal instillation
    • DOI 10.1093/toxsci/kfg243
    • Lam CW, James JT, McCluskey R, Hunter RL. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol. Sci. 77(1), 126-134 (2004). (Pubitemid 38128652)
    • (2004) Toxicological Sciences , vol.77 , Issue.1 , pp. 126-134
    • Lam, C.-W.1    James, J.T.2    McCluskey, R.3    Hunter, R.L.4
  • 37
    • 79960564450 scopus 로고    scopus 로고
    • Pulmonary fibrotic response to aspiration of multi- walled carbon nanotubes
    • Mercer RR, Hubbs AF, Scabilloni JF et al. Pulmonary fibrotic response to aspiration of multi- walled carbon nanotubes. Part. Fibre Toxicol. 8, 21 (2011).
    • (2011) Part. Fibre Toxicol , vol.8 , Issue.21
    • Mercer, R.R.1    Hubbs, A.F.2    Scabilloni, J.F.3
  • 39
    • 77957889444 scopus 로고    scopus 로고
    • Pulmonary toxicity of intratracheal instilled multiwall carbon nanotubes in male Fischer 344 rats
    • Aiso S, Yamazaki K, Umeda Y et al. Pulmonary toxicity of intratracheal instilled multiwall carbon nanotubes in male Fischer 344 rats. Ind. Health 48(6), 783-795 (2010).
    • (2010) Ind. Health , vol.48 , Issue.6 , pp. 783-795
    • Aiso, S.1    Yamazaki, K.2    Umeda, Y.3
  • 40
    • 56149090149 scopus 로고    scopus 로고
    • Inhalation versus aspiration of single walled carbon nanotubes in C57BL/6 mice: Inflammation, fibrosis, oxidative stress and mutagenesis
    • Shvedova AA, Kisin E, Murray AR et al. Inhalation versus aspiration of single walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress and mutagenesis. Am. J. Physiol. Lung Cell. Mol. Physiol. 295(4), L552-L565 (2008).
    • (2008) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.295 , Issue.4
    • Shvedova, A.A.1    Kisin, E.2    Murray, A.R.3
  • 41
    • 70449556649 scopus 로고    scopus 로고
    • Inhaled carbon nanotubes reach the subpleural tissue in mice
    • Ryman-Rasmussen JP, Cesta MF, Broday AR et al. Inhaled carbon nanotubes reach the subpleural tissue in mice. Nat. Nanotechnol. 4(11), 747-751 (2009).
    • (2009) Nat. Nanotechnol , vol.4 , Issue.11 , pp. 747-751
    • Ryman-Rasmussen, J.P.1    Cesta, M.F.2    Broday, A.R.3
  • 42
  • 43
    • 67651227154 scopus 로고    scopus 로고
    • Mechanisms of how inhaled mutiwalled carbon nanotubes suppress systemic immune function in mice
    • Mitchell LA, Lauer FT, Burchiel SW, McDonald JD. Mechanisms of how inhaled mutiwalled carbon nanotubes suppress systemic immune function in mice. Nat. Nanotechnol. 4(7), 451-456 (2009).
    • (2009) Nat. Nanotechnol , vol.4 , Issue.7 , pp. 451-456
    • Mitchell, L.A.1    Lauer, F.T.2    Burchiel, S.W.3    McDonald, J.D.4
  • 45
    • 84892144111 scopus 로고    scopus 로고
    • Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes
    • Sargent LM, Porter DW, Staska LM et al. Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes. Part. Fibre Toxicol. 11(1), 3 (2014).
    • (2014) Part. Fibre Toxicol , vol.11 , Issue.1 , pp. 3
    • Sargent, L.M.1    Porter, D.W.2    Staska, L.M.3
  • 46
    • 0025735464 scopus 로고
    • Mesothelioma dose response following intraperitoneal injection of mineral fibres
    • Davis JM, Bolton RE, Miller BG, Niven K. Mesothelioma dose response following intraperitoneal injection of mineral fibres. Int. J. Exp. Pathol. 72(3), 263-274 (1991).
    • (1991) Int. J. Exp. Pathol , vol.72 , Issue.3 , pp. 263-274
    • Davis, J.M.1    Bolton, R.E.2    Miller, B.G.3    Niven, K.4
  • 47
    • 46749153312 scopus 로고    scopus 로고
    • Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study
    • Poland CA, Duffin R, Kinloch L et al. Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat. Nanotechnol. 3(7), 423-428 (2008).
    • (2008) Nat. Nanotechnol , vol.3 , Issue.7 , pp. 423-428
    • Poland, C.A.1    Duffin, R.2    Kinloch, L.3
  • 49
    • 77957912479 scopus 로고    scopus 로고
    • Mesothelioma induction by micrometer-sized multi-walled carbon nanotube intraperitoneally injected to p53 heterozygous mice
    • Kanno J, Takagi A, Nishimura T, Hirose A. Mesothelioma induction by micrometer-sized multi-walled carbon nanotube intraperitoneally injected to p53 heterozygous mice. Toxicologist 114, A1397 (2010).
    • (2010) Toxicologist , vol.114
    • Kanno, J.1    Takagi, A.2    Nishimura, T.3    Hirose, A.4
  • 50
    • 67650742271 scopus 로고    scopus 로고
    • Absence of carcinogenic response to multiwall carbon nanotubes in 2-year bioassay in the peritoneal cavity of the rat
    • Muller J, Delos M, Panin N, Rabolli V, Huaux F, Lison D. Absence of carcinogenic response to multiwall carbon nanotubes in 2-year bioassay in the peritoneal cavity of the rat. Toxicol. Sci. 110(2), 442-448 (2009).
    • (2009) Toxicol. Sci , vol.110 , Issue.2 , pp. 442-448
    • Muller, J.1    Delos, M.2    Panin, N.3    Rabolli, V.4    Huaux, F.5    Lison, D.6
  • 51
    • 77951245017 scopus 로고    scopus 로고
    • Effects of subchronic exposure to multi-walled carbon nanotubes in mice
    • Liang G, Yin L, Zhang J et al. Effects of subchronic exposure to multi-walled carbon nanotubes in mice. J. Toxicol. Environ. Health A 73(7), 463-470 (2010).
    • (2010) J. Toxicol. Environ. Health A , vol.73 , Issue.7 , pp. 463-470
    • Liang, G.1    Yin, L.2    Zhang, J.3
  • 52
    • 84862292684 scopus 로고    scopus 로고
    • Pluronic F108 coating decreases the lung fibrosis potential of multiwall carbon nanotubes by reducing lysosomal injury
    • Wang X, Xia T, Duch MC et al. Pluronic F108 coating decreases the lung fibrosis potential of multiwall carbon nanotubes by reducing lysosomal injury. Nano Lett. 12(6), 3050-3061 (2012).
    • (2012) Nano Lett , vol.12 , Issue.6 , pp. 3050-3061
    • Wang, X.1    Xia, T.2    Duch, M.C.3
  • 53
    • 84862274677 scopus 로고    scopus 로고
    • Assessment of pulmonary fibrogenic potential of multiwalled carbon nanotubes in human lung cells
    • Mishra A, Rojanasakul Y, Chen BT, Castranova V, Mercer RR, Wang L. Assessment of pulmonary fibrogenic potential of multiwalled carbon nanotubes in human lung cells. J. Nanomater. 2012, 930931 (2012).
    • (2012) J. Nanomater , vol.2012 , pp. 930931
    • Mishra, A.1    Rojanasakul, Y.2    Chen, B.T.3    Castranova, V.4    Mercer, R.R.5    Wang, L.6
  • 56
    • 54149097729 scopus 로고    scopus 로고
    • Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells
    • Pacurari M, Yin XJ, Zhao J et al. Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells. Environ. Health Perspect. 116(9), 1211-1217 (2008).
    • (2008) Environ. Health Perspect , vol.116 , Issue.9 , pp. 1211-1217
    • Pacurari, M.1    Yin, X.J.2    Zhao, J.3
  • 57
    • 84889260511 scopus 로고    scopus 로고
    • Mechanisms of carbon nanotube-induced toxicity: Focus on pulmonary inflammation
    • Bhattacharya K, Andón FT, El-Sayed R, Fadeel B. Mechanisms of carbon nanotube-induced toxicity: focus on pulmonary inflammation. Adv. Drug Deliv. Rev. 65(15), 2087-2097 (2013).
    • (2013) Adv. Drug Deliv. Rev , vol.65 , Issue.15 , pp. 2087-2097
    • Bhattacharya, K.1    Andón, F.T.2    El-Sayed, R.3    Fadeel, B.4
  • 59
    • 84873334239 scopus 로고    scopus 로고
    • Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses
    • Azad N, Iyer AKV, Wang L, Liu Y, Lu Y, Rojanasakul Y. Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses. Nanotoxicology 7(2), 157-168 (2013).
    • (2013) Nanotoxicology , vol.7 , Issue.2 , pp. 157-168
    • Azad, N.1    Akv, I.2    Wang, L.3    Liu, Y.4    Lu, Y.5    Rojanasakul, Y.6
  • 60
    • 84880912858 scopus 로고    scopus 로고
    • Multi-walled carbon nanotubes induce human micro vascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells
    • Snyder-Talkington BN, Schwegler-Berry D, Castranova V, Qian Y, Guo NL. Multi-walled carbon nanotubes induce human micro vascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells. Part. Fibre Toxicol. 10, 35 (2013).
    • (2013) Part. Fibre Toxicol , vol.10 , Issue.35
    • Snyder-Talkington, B.N.1    Schwegler-Berry, D.2    Castranova, V.3    Qian, Y.4    Guo, N.L.5
  • 61
    • 70350192263 scopus 로고    scopus 로고
    • Induction of apoptosis in rat lung epithelial cells by multiwalled carbon nanotubes
    • Ravichandran P, Periyakaruppan A, Sadanandan B et al. Induction of apoptosis in rat lung epithelial cells by multiwalled carbon nanotubes. J. Biochem. Mol. Toxicol. 23(5) 333-344 (2009).
    • (2009) J. Biochem. Mol. Toxicol , vol.23 , Issue.5 , pp. 333-344
    • Ravichandran, P.1    Periyakaruppan, A.2    Sadanandan, B.3
  • 62
    • 79958016544 scopus 로고    scopus 로고
    • Raw single-walled carbon nanotube-induced cytotoxic effects in human bronchial epithelial cells: Comparison to asbestos
    • Pacurari M, Schwegler-Berry D, Friend S et al. Raw single-walled carbon nanotube-induced cytotoxic effects in human bronchial epithelial cells: comparison to asbestos. Toxicol. Environ. Chem. 93(5) 1045-1072 (2011).
    • (2011) Toxicol. Environ. Chem , vol.93 , Issue.5 , pp. 1045-1072
    • Pacurari, M.1    Schwegler-Berry, D.2    Friend, S.3
  • 63
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • DOI 10.1038/25292
    • Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 396(6712), 643-649 (1998). (Pubitemid 29003936)
    • (1998) Nature , vol.396 , Issue.6712 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 64
    • 84888871860 scopus 로고    scopus 로고
    • Genotoxicity and carcinogenicity risk of carbon nanotubes
    • Toyokuni S. Genotoxicity and carcinogenicity risk of carbon nanotubes. Adv. Drug Deliv. Rev. 65(15), 2098-2110 (2013).
    • (2013) Adv. Drug Deliv. Rev , vol.65 , Issue.15 , pp. 2098-2110
    • Toyokuni, S.1
  • 65
    • 61849090369 scopus 로고    scopus 로고
    • Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro
    • Lindberg HK, Falck GCM, Suhonen S et al. Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro. Toxicol. Lett. 186(3), 166-173 (2009).
    • (2009) Toxicol. Lett , vol.186 , Issue.3 , pp. 166-173
    • Lindberg, H.K.1    Gcm, F.2    Suhonen, S.3
  • 67
    • 42649085073 scopus 로고    scopus 로고
    • Non-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cells
    • Rotolia BM, Bussolatia O, Bianchia MG et al. Non-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cells. Toxicol. Lett. 178(2), 95-102 (2008).
    • (2008) Toxicol. Lett , vol.178 , Issue.2 , pp. 95-102
    • Rotolia, B.M.1    Bussolatia, O.2    Bianchia, M.G.3
  • 68
    • 84055174935 scopus 로고    scopus 로고
    • Mesenchymal cell survival in airway and interstitial pulmonary fibrosis
    • Bonner JC. Mesenchymal cell survival in airway and interstitial pulmonary fibrosis. Fibrogenesis Tissue Repair 3, 15 (2010).
    • (2010) Fibrogenesis Tissue Repair , vol.3 , Issue.15
    • Bonner, J.C.1
  • 69
    • 84890413729 scopus 로고    scopus 로고
    • IL-1R signaling is critical for regulation of multi-walled carbon nanotubes-induced acute lung inflammation in C57Bl/6 mice
    • Girtsman TA, Beamer CA, Wu N, Buford M, Holian A. IL-1R signaling is critical for regulation of multi-walled carbon nanotubes-induced acute lung inflammation in C57Bl/6 mice. Nanotoxicology 8(1), 17-27 (2014).
    • (2014) Nanotoxicology , vol.8 , Issue.1 , pp. 17-27
    • Girtsman, T.A.1    Beamer, C.A.2    Wu, N.3    Buford, M.4    Holian, A.5
  • 70
    • 84055177567 scopus 로고    scopus 로고
    • Multiwalled carbon nanotubes induce a fibrogenic response by stimulating reactive oxygen species production, activating NF-κB signaling, and promoting fibroblast-to-myofibroblast transformation
    • He X, Young S, Schwegler-Berry D, Chisholm WP, Fernback JE, Ma Q. Multiwalled carbon nanotubes induce a fibrogenic response by stimulating reactive oxygen species production, activating NF-κB signaling, and promoting fibroblast-to-myofibroblast transformation. Chem. Res. Toxicol. 24(12), 2237-2248 (2011).
    • (2011) Chem. Res. Toxicol , vol.24 , Issue.12 , pp. 2237-2248
    • He, X.1    Young, S.2    Schwegler-Berry, D.3    Chisholm, W.P.4    Fernback, J.E.5    Ma, Q.6
  • 72
    • 77957266722 scopus 로고    scopus 로고
    • Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes
    • Mercer RR, Hubbs AF, Scabilloni JF et al. Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes. Part. Fibre Toxicol. 7, 28 (2010).
    • (2010) Part. Fibre Toxicol , vol.7 , Issue.28
    • Mercer, R.R.1    Hubbs, A.F.2    Scabilloni, J.F.3
  • 73
    • 77952317021 scopus 로고    scopus 로고
    • Asbestos, carbon nanotubes and the pleural mesothelium: A review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma
    • Donaldson K, Murphy FA, Duffin R, Poland CA. Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma. Part. Fibre Toxicol. 7, 5 (2010).
    • (2010) Part. Fibre Toxicol , vol.7 , Issue.5
    • Donaldson, K.1    Murphy, F.A.2    Duffin, R.3    Poland, C.A.4
  • 74
    • 79959228468 scopus 로고    scopus 로고
    • Dose-response relationships in expression of biomarkers of cell proliferation in in vitro assays and inhalation experiments
    • Shukla A, Vacek P, Mossman BT. Dose-response relationships in expression of biomarkers of cell proliferation in in vitro assays and inhalation experiments. Nonlinearity Biol. Toxicol. Med. 2(2), 117-128 (2004).
    • (2004) Nonlinearity Biol. Toxicol. Med , vol.2 , Issue.2 , pp. 117-128
    • Shukla, A.1    Vacek, P.2    Mossman, B.T.3
  • 75
    • 79960265384 scopus 로고    scopus 로고
    • Carbon nanotubes induce malignant transformation and tumorigenesis of human lung epithelial cells
    • Wang L, Luanpitpong S, Castranova V et al. Carbon nanotubes induce malignant transformation and tumorigenesis of human lung epithelial cells. Nano Lett. 11(7), 2796-2803 (2011).
    • (2011) Nano Lett , vol.11 , Issue.7 , pp. 2796-2803
    • Wang, L.1    Luanpitpong, S.2    Castranova, V.3
  • 76
    • 84884946142 scopus 로고    scopus 로고
    • Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared with asbestos on human lung small airway epithelial cells
    • doi:10.3109/17435390.2013.801089 Epub ahead of print
    • Wang L, Stueckle T, Mishra A et al. Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared with asbestos on human lung small airway epithelial cells. Nanotoxicology doi:10.3109/17435390. 2013.801089 (2013) (Epub ahead of print).
    • (2013) Nanotoxicology
    • Wang, L.1    Stueckle, T.2    Mishra, A.3
  • 77
    • 84884963639 scopus 로고    scopus 로고
    • Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2
    • Lohcharoenkal W, Wang L, Stueckle TA et al. Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2. ACS Nano 7(9), 7711-7723 (2013).
    • (2013) ACS Nano , vol.7 , Issue.9 , pp. 7711-7723
    • Lohcharoenkal, W.1    Wang, L.2    Stueckle, T.A.3
  • 78
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 100(1), 57-70 (2000). (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 79
    • 34447543913 scopus 로고    scopus 로고
    • Cellular Senescence in Cancer and Aging
    • DOI 10.1016/j.cell.2007.07.003, PII S0092867407008902
    • Collado M, Blasco MA, Serrano M. Cellular senescence in cancer and aging. Cell 130(2), 223-233 (2007). (Pubitemid 47081143)
    • (2007) Cell , vol.130 , Issue.2 , pp. 223-233
    • Collado, M.1    Blasco, M.A.2    Serrano, M.3
  • 80
    • 84885458175 scopus 로고    scopus 로고
    • Focal amplification of HOXD-harboring chromosome region is implicated in multiple-walled carbon nanotubes-induced carcinogenicity
    • Wu P, Yuan SS, Ho CC et al. Focal amplification of HOXD-harboring chromosome region is implicated in multiple-walled carbon nanotubes-induced carcinogenicity. Nano Lett. 13(10), 4632-4641 (2013).
    • (2013) Nano Lett , vol.13 , Issue.10 , pp. 4632-4641
    • Wu, P.1    Yuan, S.S.2    Ho, C.C.3
  • 82
    • 0037228921 scopus 로고    scopus 로고
    • Apoptosis and cancer: Basic mechanisms and therapeutic opportunities in the postgenomic era
    • Stenner-Liewen F, Reed JC. Apoptosis and cancer: basic mechanisms and therapeutic opportunities in the postgenomic era. Cancer Res. 63(1), 263-268 (2003). (Pubitemid 36070449)
    • (2003) Cancer Research , vol.63 , Issue.1 , pp. 263-268
    • Stenner-Liewen, F.1    Reed, J.C.2
  • 83
    • 0029976723 scopus 로고    scopus 로고
    • P53 tumor suppressor gene: At the crossroads of molecular carcinogenesis, molecular epidemiology, and cancer risk assessment
    • Harris CC. p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology, and cancer risk assessment. Environ. Health Perspect. 104(Suppl. 3), 435-439 (1996). (Pubitemid 26196382)
    • (1996) Environmental Health Perspectives , vol.104 , Issue.SUPPL. 3 , pp. 435-439
    • Harris, C.C.1
  • 84
    • 81355127254 scopus 로고    scopus 로고
    • Extracellular matrix determinants of proteolytic and non-proteolytic cell migration
    • Wolf K, Friedl P. Extracellular matrix determinants of proteolytic and non-proteolytic cell migration. Trends Cell Biol. 21(12), 736-744 (2011).
    • (2011) Trends Cell Biol , vol.21 , Issue.12 , pp. 736-744
    • Wolf, K.1    Friedl, P.2
  • 85
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: Diversity and escape mechanisms
    • DOI 10.1038/nrc1075
    • Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat. Rev. Cancer 3(5), 362-374 (2003). (Pubitemid 37328856)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.5 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 86
    • 33751252276 scopus 로고    scopus 로고
    • Cancer Metastasis: Building a Framework
    • DOI 10.1016/j.cell.2006.11.001, PII S0092867406014140
    • Gupta GP, Massague J. Cancer metastasis: building a framework. Cell 127(4), 679-695 (2006). (Pubitemid 44781029)
    • (2006) Cell , vol.127 , Issue.4 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 90
    • 0011928103 scopus 로고    scopus 로고
    • Occupational airborne skin diseases
    • Kanerva L, Elsner P, Wahlberg JE, Maibach HI (Eds). Springer-Verlag, Berlin, Germany
    • Lachapelle JM. Occupational airborne skin diseases. In:. Handbook of Occupational Dermatology. Kanerva L, Elsner P, Wahlberg JE, Maibach HI (Eds). Springer-Verlag, Berlin, Germany, 193-199 (2002).
    • (2002) Handbook of Occupational Dermatology , pp. 193-199
    • Lachapelle, J.M.1
  • 91
    • 32044472267 scopus 로고    scopus 로고
    • Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice
    • DOI 10.1016/j.carbon.2005.08.006, PII S0008622305004811, Toxicology of Carbon Nanimaterials
    • Koyama S, Endo M, Kim YA et al. Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice. Carbon 44(6), 1079-1092 (2006). (Pubitemid 43202165)
    • (2006) Carbon , vol.44 , Issue.6 , pp. 1079-1092
    • Koyama, S.1    Endo, M.2    Kim, Y.-A.3    Hayashi, T.4    Yanagisawa, T.5    Osaka, K.6    Koyama, H.7    Haniu, H.8    Kuroiwa, N.9
  • 93
    • 60349123278 scopus 로고    scopus 로고
    • Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes
    • Murray AR, Kisin E, Leonard SS et al. Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology 257(3), 161-171 (2009).
    • (2009) Toxicology , vol.257 , Issue.3 , pp. 161-171
    • Murray, A.R.1    Kisin, E.2    Leonard, S.S.3
  • 94
    • 2442624457 scopus 로고    scopus 로고
    • Basics of skin structure
    • Wickett RR. Basics of skin structure. J. Cosmet. Sci. 55(1), 132-133 (2004).
    • (2004) J. Cosmet. Sci , vol.55 , Issue.1 , pp. 132-133
    • Wickett, R.R.1
  • 95
    • 80051680304 scopus 로고    scopus 로고
    • Assessment of dermal irritation potential of MWCNT
    • Park YH, Jeong SH, Lee EY et al. Assessment of dermal irritation potential of MWCNT. Toxicol. Environ. Health. Sci. 2(2), 115-118 (2010).
    • (2010) Toxicol. Environ. Health. Sci , vol.2 , Issue.2 , pp. 115-118
    • Park, Y.H.1    Jeong, S.H.2    Lee, E.Y.3
  • 96
    • 80053191375 scopus 로고    scopus 로고
    • Multi-walled carbon nanotubes induce cytotoxicity, genotoxicity and apoptosis in normal human dermal fibroblast cells
    • Patlolla A, Knighten B, Tchounwou P. Multi-walled carbon nanotubes induce cytotoxicity, genotoxicity and apoptosis in normal human dermal fibroblast cells. Ethn. Dis. 20(1 Suppl. 1), S1-S72 (2010).
    • (2010) Ethn. Dis , vol.20 , Issue.1 SUPPL. 1
    • Patlolla, A.1    Knighten, B.2    Tchounwou, P.3
  • 97
    • 71549153541 scopus 로고    scopus 로고
    • Using carbon nanotubes to induce micronuclei and double strand breaks of the DNA in human cells
    • Cveticanin J, Joksic G, Leskovac A, Petrovic S, Sobot AV, Neskovic O. Using carbon nanotubes to induce micronuclei and double strand breaks of the DNA in human cells. Nanotechnology 21(1), 015102 (2010).
    • (2010) Nanotechnology , vol.21 , Issue.1 , pp. 015102
    • Cveticanin, J.1    Joksic, G.2    Leskovac, A.3    Petrovic, S.4    Sobot, A.V.5    Neskovic, O.6
  • 98
    • 33748746916 scopus 로고    scopus 로고
    • Multi-walled carbon nanotube exposure alters protein expression in human keratinocytes
    • DOI 10.1016/j.nano.2006.07.005, PII S1549963406001031
    • Witzmann FA, Monteiro-Riviere NA. Multi-walled carbon nanotube exposure alters protein expression in human keratinocytes. Nanomedicine 2(3), 158-168 (2006). (Pubitemid 44403217)
    • (2006) Nanomedicine: Nanotechnology, Biology, and Medicine , vol.2 , Issue.3 , pp. 158-168
    • Witzmann, F.A.1    Monteiro-Riviere, N.A.2
  • 99
    • 34047101423 scopus 로고    scopus 로고
    • Biological interactions of functionalized single-wall carbon nanotubes in human epidermal keratinocytes
    • DOI 10.1080/10915810701225133, PII 776090339
    • Zhang LW, Zeng L, Barron AR, Monteiro-Riviere NA. Biological interactions of functionalized single-wall carbon nanotubes in human epidermal keratinocytes. Int. J. Toxicol. 26(2), 103-113 (2007). (Pubitemid 46514921)
    • (2007) International Journal of Toxicology , vol.26 , Issue.2 , pp. 103-113
    • Zhang, L.W.1    Zeng, L.2    Barron, A.R.3    Monteiro-Riviere, N.A.4
  • 100
    • 78650897853 scopus 로고    scopus 로고
    • Influences of acid-treated multiwalled carbon nanotubes on fibroblasts: Proliferation, adhesion, migration, and wound healing
    • Zhang Y, Wang B, Meng X, Sun G, Gao C. Influences of acid-treated multiwalled carbon nanotubes on fibroblasts: proliferation, adhesion, migration, and wound healing. Ann. Biomed. Eng. 39(1), 414-426 (2011).
    • (2011) Ann. Biomed. Eng , vol.39 , Issue.1 , pp. 414-426
    • Zhang, Y.1    Wang, B.2    Meng, X.3    Sun, G.4    Gao, C.5
  • 101
    • 0031656215 scopus 로고    scopus 로고
    • Physiology and healing dynamics of chronic cutaneous wounds
    • Stadelmann WK, Digenis AG, Tobin GR. Physiology and healing dynamics of chronic cutaneous wounds. Am. J. Surg. 176(2A Suppl.), S26-S38 (1998).
    • (1998) Am. J. Surg , vol.176 , Issue.2 SUPPL.
    • Stadelmann, W.K.1    Digenis, A.G.2    Tobin, G.R.3


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