Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors

Journal of Cell Science

Volumn 127, Issue 13, 2014, Pages 2873-2884

  Bertrand, Anne T ^a,b,c,d   Ziaei, Simindokht ^a,b,c,d   Ehret, Camille ^a,b,c,d   Duchemin, Hélène ^a,b,c,d   Mamchaoui, Kamel ^a,b,c,d   Bigot, Anne ^a,b,c,d   Mayer, Michéle ^e   Quijano Roy, Susana ^f   Desguerre, Isabelle ^g   Lainé, Jeanne ^a,b,c,d   Yaou, Rabah Ben ^a,b,c,d   Bonne, Giséle ^a,b,c,d,h   Coirault, Catherine ^a,b,c,d  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c CNRS   (France)

^d Institut de Myologie   (France)

^e Hô pital Trousseau Centre de Référence des maladies neuromusculaire de l'Est Parisien Service de Service de Neuropédiatrie   (France)

^f Groupe Hospitalier Universitaire Paris Ile de France Ouest Site Raymond Poincaré   (France)

^g Hô pital Necker Enfants Malades Centre de Référence des Maladies Neuromusculaires Unitéde Neuropédiatrie   (France)

^h PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Cell microenvironment; LMNA; Mechanosensitivity; Muscular dystrophy; Yes associated protein

Indexed keywords

LAMIN A; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; YES ASSOCIATED PROTEIN; LMNA PROTEIN, HUMAN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ACTIN FILAMENT; ARTICLE; CELL ADHESION; CELL DAMAGE; CELL STRUCTURE; CELLULAR PARAMETERS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSKELETAL TENSION; CYTOSKELETON; DEPOLYMERIZATION; DOWN REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MECHANOTRANSDUCTION; MICROTUBULE; MUSCULAR DYSTROPHY; MUTATION; MYOBLAST; MYOTUBE; PRIORITY JOURNAL; RIGIDITY; STRESS FIBER; TENSION; TISSUE STIFFNESS; CONFOCAL MICROSCOPY; CYTOLOGY; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELLULAR MICROENVIRONMENT; HUMANS; LAMIN TYPE A; MICROSCOPY, CONFOCAL; MUTATION; MYOBLASTS; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION;

EID: 84903764153     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.144907     Document Type: Article

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