DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death

Human Molecular Genetics

Volumn 21, Issue 5, 2012, Pages 1037-1048

  Bertrand, Anne T ^a,b   Renou, Laure ^a,b   Papadopoulos, Aurélie ^a,b   Beuvin, Maud ^a,b   Lacène, Emmanuelle ^a,b   Massart, Catherine ^a,b   Ottolenghi, Chris ^c   Decostre, Valérie ^a,b   Maron, Sophia ^d   Schlossarek, Saskia ^d   Cattin, Marie Elodie ^a,b   Carrier, Lucie ^a,b,d   Malissen, Marie ^e,f,g   Arimura, Takuro ^a,b,i   Bonne, Gisèle ^a,b,h  

^a Sorbonne Université   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^f INSERM   (France)

^g CNRS   (France)

^h PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

ⁱ TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN A; LAMIN C; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEATH; EMBRYO DEVELOPMENT; GENE MUTATION; GLUCOSE HOMEOSTASIS; HYPOGLYCEMIA; LIVER; METABOLIC DISORDER; MOUSE; MUSCULAR DYSTROPHY; NONHUMAN; PREMATURE DEATH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TISSUE DIFFERENTIATION;

ADIPOCYTES; ADIPOGENESIS; ANIMALS; ANIMALS, NEWBORN; CELL NUCLEUS; EMBRYO, MAMMALIAN; GENE KNOCK-IN TECHNIQUES; GROWTH DISORDERS; HEART; LAMIN TYPE A; LAMIN TYPE B; LIVER; METABOLIC DISEASES; MICE; MORTALITY, PREMATURE; MUSCLE, SKELETAL; MUTANT PROTEINS; MYOCYTES, CARDIAC; NUCLEAR LAMINA; ORGAN SIZE; PHENOTYPE; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION, GENETIC;

EID: 84856951638     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr534     Document Type: Article

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