Histone and DNA methylation-mediated epigenetic downregulation of endothelial kruppel-like factor 2 by low-density lipoprotein cholesterol

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 8, 2013, Pages 1936-1942

  Kumar, Ajay ^a   Kumar, Santosh ^a   Vikram, Ajit ^a   Hoffman, Timothy A ^a   Naqvi, Asma ^a   Lewarchik, Christopher M ^a   Kim, Young Rae ^a   Irani, Kaikobad ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Cholesterol, LDL; DNA methyltransferase; Endothelial cells; Histone methyltransferase; KLF2

Indexed keywords

DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; HISTONE METHYLTRANSFERASE; KRUPPEL LIKE FACTOR 2; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METHYL CPG BINDING PROTEIN 2; MYOCYTE ENHANCER FACTOR 2; NITRIC OXIDE SYNTHASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROCOAGULANT; THROMBOMODULIN; TRANSCRIPTION FACTOR EZH2;

ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; DNA BINDING; DNA METHYLATION; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; EPIGENETICS; GENE MUTATION; GENE OVEREXPRESSION; GENE SILENCING; HISTONE METHYLATION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; THROMBOCYTE RICH PLASMA; UPREGULATION;

CHOLESTEROL, LDL; DNA METHYLTRANSFERASE; ENDOTHELIAL CELLS; HISTONE METHYLTRANSFERASE; KLF2;

ATHEROSCLEROSIS; CHOLESTEROL, LDL; DNA METHYLATION; DOWN-REGULATION; ENDOTHELIAL CELLS; EPIGENESIS, GENETIC; HISTONES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MADS DOMAIN PROTEINS; MEF2 TRANSCRIPTION FACTORS; METHYL-CPG-BINDING PROTEIN 2; MYOGENIC REGULATORY FACTORS; PHENOTYPE; POLYCOMB REPRESSIVE COMPLEX 2; PROMOTER REGIONS, GENETIC; THROMBOSIS; TRANSCRIPTION, GENETIC; VASCULITIS;

EID: 84881027287     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.113.301765     Document Type: Article

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