Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs

Nature

Volumn 511, Issue 7507, 2014, Pages 46-51

  Lopez Rios, Javier ^a   Duchesne, Amandine ^a,b   Speziale, Dario ^a   Andrey, Guillaume ^c   Peterson, Kevin A ^d   Germann, Philipp ^e   Ünal, Erkan ^a,e   Liu, Jing ^d   Floriot, Sandrine ^b   Barbey, Sarah ^f   Gallard, Yves ^f   Müller Gerbl, Magdalena ^g   Courtney, Andrew D ^h   Klopp, Christophe ⁱ   Rodriguez, Sabrina ^b,m   Ivanek, Robert ^a,j   Beisel, Christian ^e   Wicking, Carol ^h   Iber, Dagmar ^e   Robert, Benoit ^k   McMahon, Andrew P ^d   Duboule, Denis ^c,l   Zeller, Rolf ^a   more..

^a UNIVERSITY OF BASEL   (Switzerland)

^b UMR1313 GÉNÉTIQUE ANIMALE ET BIOLOGIE INTÉGRATIVE   (France)

^c EPFL   (Switzerland)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e ETH ZURICH   (Switzerland)

^f Domaine Expérimental du Pin Au Haras   (France)

^g UNIVERSITY OF BASEL   (Switzerland)

^h UNIVERSITY OF QUEENSLAND   (Australia)

ⁱ CEMAGREF   (France)

^j SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^k CNRS   (France)

^l UNIVERSITY OF GENEVA   (Switzerland)

^m UMR792 INGÉNIERIE DES SYSTÈMES BIOLOGIQUES ET DES PROCÉDÉS   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN;

EVOLUTIONARY BIOLOGY; GENE EXPRESSION; LIMB; MORPHOLOGY; SIGNAL; UNGULATE;

ARTICLE; ARTIODACTYLA; CATTLE; CONTROLLED STUDY; DNA MODIFICATION; EMBRYO; FINGER; GENE; GENE EXPRESSION; GENE INACTIVATION; LIMB BUD; LIMB DEVELOPMENT; MESENCHYME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PTCH1 GENE; SIGNAL TRANSDUCTION; SPECIES COMPARISON; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; BIOLOGICAL EVOLUTION; BODY PATTERNING; CATTLE; EXTREMITIES; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; LIMB BUDS; MALE; MESODERM; MICE; MICE, TRANSGENIC; RECEPTORS, CELL SURFACE; REGULATORY SEQUENCES, NUCLEIC ACID;

EID: 84903747246     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13289     Document Type: Article

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