GLI3 Constrains Digit Number by Controlling Both Progenitor Proliferation and BMP-Dependent Exit to Chondrogenesis

Developmental Cell

Volumn 22, Issue 4, 2012, Pages 837-848

  Lopez Rios, Javier ^a   Speziale, Dario ^a   Robay, Dimitri ^a,d   Scotti, Martina ^b   Osterwalder, Marco ^a   Nusspaumer, Gretel ^a   Galli, Antonella ^a,e   Holländer, Georg A ^a,c   Kmita, Marie ^b   Zeller, Rolf ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d BASILEA PHARMACEUTICA INTERNATIONAL LTD   (Switzerland)

^e NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CYCLIN DEPENDENT KINASE 6; GREMLIN1 PROTEIN; PROTEIN; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CHONDROGENESIS; EMBRYO; FINGER; GENE EXPRESSION REGULATION; GENE INACTIVATION; HAND; LIMB DEVELOPMENT; MOUSE; NONHUMAN; POLYDACTYLY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEM CELL;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BODY PATTERNING; BONE MORPHOGENETIC PROTEINS; CELL PROLIFERATION; CHONDROGENESIS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HAND DEFORMITIES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LIMB BUDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYDACTYLY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; S PHASE; STEM CELLS;

ERINACEIDAE; PYRONIA TITHONUS; TETRAPODA; VERTEBRATA;

EID: 84859859994     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2012.01.006     Document Type: Article

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