Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterning

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 12, 2010, Pages 5489-5494

  Bouldin, Cortney M ^a   Gritli Linde, Amel ^b   Ahn, Sohyun ^c   Harfe, Brian D ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Limb patterning; Polydactyly; Shh signaling

Indexed keywords

SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; APICAL ECTODERMAL RIDGE; ARTICLE; CONTROLLED STUDY; ECTODERM; EMBRYONIC STRUCTURES; GENE EXPRESSION REGULATION; IMMUNOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIMB BUD; LOSS OF FUNCTION MUTATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VERTEBRATE;

ANIMALS; BODY PATTERNING; ECTODERM; EXTREMITIES; FEEDBACK, PHYSIOLOGICAL; FEMALE; FIBROBLAST GROWTH FACTORS; HEDGEHOG PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MODELS, BIOLOGICAL; POLYDACTYLY; PREGNANCY; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; STOCHASTIC PROCESSES;

ERINACEIDAE; VERTEBRATA;

EID: 77950428746     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912818107     Document Type: Article

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