C-Src drives intestinal regeneration and transformation

EMBO Journal

Volumn 33, Issue 13, 2014, Pages 1474-1491

  Cordero, Julia B ^a   Ridgway, Rachel A ^a   Valeri, Nicola ^b   Nixon, Colin ^a   Frame, Margaret C ^d   Muller, William J ^c   Vidal, Marcos ^a   Sansom, Owen J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Apc; intestinal stem cells; regeneration; Src; tumourigenesis

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE FYN; PROTEIN KINASE YES; RAS PROTEIN; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; GENE FUNCTION; GENETIC GAIN; GENETIC TRANSFORMATION; HOMEOSTASIS; HYPERPLASIA; IN VIVO STUDY; INTESTINAL REGENERATION; INTESTINAL STEM CELL; INTESTINE CELL; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; REGENERATION; STEM CELL; UPREGULATION;

APC; INTESTINAL STEM CELLS; REGENERATION; SRC; TUMOURIGENESIS;

ANIMALS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE AMPLIFICATION; HUMANS; INTESTINAL MUCOSA; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, INVERTEBRATE PEPTIDE; REGENERATION; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR; STEM CELLS;

EID: 84903735725     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1002/embj.201387454     Document Type: Article

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