Csk-deficient boundary cells are eliminated from normal drosophila epithelia by exclusion, migration, and apoptosis

Developmental Cell

Volumn 10, Issue 1, 2006, Pages 33-44

  Vidal, Marcos ^a   Larson, David E ^a   Cagan, Ross L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell bio; Cell cycle; Signaling

Indexed keywords

CADHERIN; CATENIN; GELATINASE A; PROTEIN CSK; PROTEIN P120; PROTEIN TYROSINE KINASE; RHO FACTOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVITY; EPITHELIUM CELL; MICROENVIRONMENT; MOLECULAR MECHANICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; ARMADILLOS; BETA-GALACTOSIDASE; CELL ADHESION MOLECULES; CELL MOVEMENT; DROSOPHILA; DROSOPHILA PROTEINS; EPITHELIAL CELLS; EPITHELIUM; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MAP KINASE KINASE 4; MATRIX METALLOPROTEINASE 2; MICROSCOPY, ELECTRON, SCANNING; MODELS, BIOLOGICAL; MUTAGENESIS; PHOSPHOPROTEINS; PHOTORECEPTORS, INVERTEBRATE; PROTEIN-TYROSINE KINASES; RETINA; RHO GTP-BINDING PROTEINS; TIME FACTORS; WING;

ANIMALIA;

EID: 29744462234     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2005.11.007     Document Type: Article

References (56)

1. T. Adachi-Yamada K. Fujimura-Kamada Y. Nishida K. Matsumoto Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing Nature 400 1999 166-169
2. R. Albertson C. Chabu A. Sheehan C. Doe Scribble protein domain mapping reveals a multistep localization mechanism and domains necessary for establishing cortical polarity J. Cell Sci. 117 2004 6061-6070
3. S. Bao R. Cagan Preferential adhesion mediated by Hibris and Roughest regulates morphogenesis and patterning in the Drosophila eye Dev. Cell 8 2005 925-935
4. K. Basler G. Struhl Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein Nature 368 1994 208-214
5. D. Bilder M. Li N. Perrimon Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors Science 289 2000 113-116
6. J.S. Biscardi A.P. Belsches S.J. Parsons Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells Mol. Carcinog. 21 1998 261-272
7. C.B. Brachmann O.W. Jassim B.D. Wachsmuth R.L. Cagan The Drosophila Bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation Curr. Biol. 10 2000 547-550
8. A.H. Brand N. Perrimon Targeted gene expression as a means of altering cell fates and generating dominant phenotypes Development 118 1993 401-415
9. A.M. Brumby H.E. Richardson scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila EMBO J. 22 2003 5769-5779
10. A.M. Brumby H.E. Richardson Using Drosophila melanogaster to map human cancer pathways Nat. Rev. Cancer 5 2005 626-639
11. J.L. Gomez-Skarmeta R. Diez del Corral E. de la Calle-Mustienes D. Ferre-Marco J. Modolell Araucan and caupolican, two members of the novel iroquois complex, encode homeoproteins that control proneural and vein-forming genes Cell 85 1996 95-105
12. S. Grimm G.O. Pflugfelder Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless Science 271 1996 1601-1604
13. N.A. Grzeschik E. Knust IrreC/rst-mediated cell sorting during Drosophila pupal eye development depends on proper localisation of DE-cadherin Development 132 2005 2035-2045
14. B.M. Gumbiner Regulation of cadherin-mediated adhesion in morphogenesis Nat. Rev. Mol. Cell Biol. 6 2005 622-634
15. K.F. Harvey C.M. Pfleger I.K. Hariharan The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis Cell 114 2003 457-467
16. C.R. Hauck D.A. Hsia X.S. Puente D.A. Cheresh D.D. Schlaepfer FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth EMBO J. 21 2002 6289-6302
17. T. Hayashi R.W. Carthew Surface mechanics mediate pattern formation in the developing retina Nature 431 2004 647-652
18. C. Huang Z. Rajfur C. Borchers M.D. Schaller K. Jacobson JNK phosphorylates paxillin and regulates cell migration Nature 424 2003 219-223
19. J.R. Huh M. Guo B.A. Hay Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role Curr. Biol. 14 2004 1262-1266
20. R.O. Hynes Integrins: Bidirectional, allosteric signaling machines Cell 110 2002 673-687
21. R.B. Irby T.J. Yeatman Role of Src expression and activation in human cancer Oncogene 19 2000 5636-5642
22. A.B. Jaffe A. Hall RHO GTPases: Biochemistry and biology Annu. Rev. Cell Dev. Biol. 10 2005 247-269
23. O.W. Jassim J.L. Fink R.L. Cagan Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response EMBO J. 22 2003 5622-5632
24. Y.S. Lee R.W. Carthew Making a better RNAi vector for Drosophila: Use of intron spacers Methods 30 2003 322-329
25. L. Lim E. Manser T. Leung C. Hall Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways Eur. J. Biochem. 242 1996 171-185
26. E. Martin-Blanco A. Gampel J. Ring K. Virdee N. Kirov A.M. Tolkovsky A. Martinez-Arias puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila Genes Dev. 12 1998 557-570
27. T. Masaki M. Okada M. Tokuda Y. Shiratori O. Hatase M. Shirai M. Nishioka M. Omata Reduced C-terminal Src kinase (Csk) activities in hepatocellular carcinoma Hepatology 29 1999 379-384
28. D.G. McEwen M. Peifer Puckered, a Drosophila MAPK phosphatase, ensures cell viability by antagonizing JNK-induced apoptosis Development 17 2005 3935-3946
29. M.A. Miller I.A. Malik M.A. Shenk R.E. Steele The Src/Csk regulatory circuit arose early in metazoan evolution Oncogene 19 2000 3925-3930
30. A.J. Minn G.P. Gupta P.M. Siegel P.D. Bos W. Shu D.D. Giri A. Viale A.B. Olshen W.L. Gerald J. Massague Genes that mediate breast cancer metastasis to lung Nature 436 2005 518-524
31. E. Moreno K. Basler G. Morata Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development Nature 416 2002 755-759
32. S.H. Myster R. Cavallo C.T. Anderson D.T. Fox M. Peifer Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component J. Cell Biol. 160 2003 433-449
33. A. Pacquelet L. Lin P. Rorth Binding site for p120/delta-catenin is not required for Drosophila E-cadherin function in vivo J. Cell Biol. 160 2003 313-319
34. A. Page-McCaw J. Serano J.M. Sante G.M. Rubin Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development Dev. Cell 4 2003 95-106
35. R.A. Pagliarini T. Xu A genetic screen in Drosophila for metastatic behavior Science 302 2003 1227-1231
36. J.C. Pastor-Pareja F. Grawe E. Martin-Blanco A. Garcia-Bellido Invasive cell behavior during Drosophila imaginal disc eversion is mediated by the JNK signaling cascade Dev. Cell 7 2004 387-399
37. A.K. Perl P. Wilgenbus U. Dahl H. Semb G. Christofori A causal role for E-cadherin in the transition from adenoma to carcinoma Nature 392 1998 190-193
38. J. Pettitt E.A. Cox I.D. Broadbent A. Flett J. Hardin The Caenorhabditis elegans p120 catenin homologue, JAC-1, modulates cadherin-catenin function during epidermal morphogenesis J. Cell Biol. 162 2003 15-22
39. M. Ramet R. Lanot D. Zachary P. Manfruelli JNK signaling pathway is required for efficient wound healing in Drosophila Dev. Biol. 241 2002 145-156
40. R.D. Read E.A. Bach R.L. Cagan Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways Mol. Cell. Biol. 24 2004 6676-6689
41. A.B. Reynolds A. Roczniak-Ferguson Emerging roles for p120-catenin in cell adhesion and cancer Oncogene 23 2004 7947-7956
42. A.B. Reynolds D.J. Roesel S.B. Kanner J.T. Parsons Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene Mol. Cell. Biol. 9 1989 629-638
43. H.D. Ryoo T. Gorenc H. Steller Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways Dev. Cell 7 2004 491-501
44. A. Soubry J. van Hengel E. Parthoens C. Colpaert E. Van Marck D. Waltregny A.B. Reynolds F. van Roy Expression and nuclear location of the transcriptional repressor Kaiso is regulated by the tumor microenvironment Cancer Res. 65 2005 2224-2233
45. O. Speck S.C. Hughes N.K. Noren R.M. Kulikauskas R.G. Fehon Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity Nature 421 2003 83-87
46. S.A. Speicher U. Thomas U. Hinz E. Knust The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: Control of cell proliferation Development 120 1994 535-544
47. R.A. Stewart D.M. Li H. Huang T. Xu A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila Oncogene 22 2003 6436-6444
48. B.E. Stronach N. Perrimon Stress signaling in Drosophila Oncogene 18 1999 6172-6182
49. R.S. Stowers T.L. Schwarz A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype Genetics 152 1999 1631-1639
50. M. Takahashi F. Takahashi K. Ui-Tei T. Kojima K. Saigo Requirements of genetic interactions between Src42A, armadillo and shotgun, a gene encoding E-cadherin, for normal development in Drosophila Development 132 2005 2547-2559
51. H. Takeda A. Nagafuchi S. Yonemura S. Tsukita J. Behrens W. Birchmeier V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and β catenin is not required for the shift J. Cell Biol. 131 1995 1839-1847
52. S. Wei Z. Xie E. Filenova K. Brew Drosophila TIMP is a potent inhibitor of MMPs and TACE: Similarities in structure and function to TIMP-3 Biochemistry 42 2003 12200-12207
53. T. Xu G.M. Rubin Analysis of genetic mosaics in developing and adult Drosophila tissues Development 117 1993 1223-1237
54. T.J. Yeatman A renaissance for SRC Nat. Rev. Cancer 4 2004 470-480
55. J. Zeitler C.P. Hsu H. Dionne D. Bilder Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble J. Cell Biol. 167 2004 1137-1146
56. S. Zrihan-Licht J. Lim I. Keydar M.X. Sliwkowski J.E. Groopman H. Avraham Association of csk-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cells J. Biol. Chem. 272 1997 1856-1863